Treatment:
1. Surgery - Breast-conserving surgery (❌) or modified radial ❌ (removal of entire breast with or without breast reconstruction)
2. Radiation - Mostly used in adjuvant setting, can be targeted or generalized, dose determined by ❌ of disease, may be used in Stage IV to palliate ❌ for metastases
3. Systemic Therapy - Adjucant: Chemotherapy, endocrine / hormonal therapy, targeted therapy. Reason for ❌ reduction in developed countries.
Chemo:
- Chemo regimens ❌ regardless of hormonal status, but anti-HER2 therapy added on to those HER2 ❌
- ❌ (if node positive) appear to have most evidence
Endocrine:
- Used to decrease risk of ❌, initiated ❌ chemotherapy complete
Targeted Anti-HER2 Therapy:
- All are ❌ – need baseline ECHO and follow up
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