Pathology of MS:
Trigger = ❌ immune response. Primed ❌ lymphocytes cross ❌. Upregulation of ❌ causes ❌,
Inflammation -
❌ autoimmune response involving INF-g, IL-17, TNF-b.
❌ cell mediated ❌ - ❌ myelin destruction
❌ -
Destroy myelin ❌, damage ❌dendrocytes. Demyelination leads to ❌ damage
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Th1 lymphocytic
Th1 lymphocytic