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Motor unit
Neuromuscular junction structure
- schwann cell forms lid over junctional cleft
-membrane thrown into junctional folds to increase SA
- acetylcholine diffuses through junctional cleft
How drugs can modify synaptic (neuromuscular) transmission
Key steps in neuromuscular transmission
Prejunctional events of neuromuscular transmission
Drugs acting prejunctionally to inhibit neuromuscular transmission
Post-junctional events in neuromuscular transmission
The nicotinic ach receptor
Drugs acting postjunctionally to inhibit neuromuscular transmission
Clinical uses of reversible competitive antagonists
Depolarising muscle relaxants
Anticholinestherase drugs
