BMS04 - Genes and gene expression Flashcards on BMS04-1039-Lec - Control of gene expression 2 (Epigenetics, Chromatin, small RNAs), created by Evian Chai on 16/04/2020.
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Created by Evian Chai
over 4 years ago
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Created by Evian Chai
over 4 years ago
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Do epigenitical changes involve changes in DNA?
What are two mechanisms of epigenetical modification?
What are chromatins made of?
What is the structure of a nucleosome?
What are histones?
What are the primary targets of histone modificaton? How do they impact the chromatin?
Acetylation can turn genes
Methylation can turn genes
Phosphorylation can turn genes
When does DNA methylation happen ? What about de novo?
What is the only base able to be methylated?
What are Cp6 Islands?
Where are they usually?
What does the epigenetic code consist of?
Are epigenetical changes reversible?
What does SAHA (form of epigenetic therapy) do?
How does 5-azacytidine treat myelodysplastic syndrome?
