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Created by Evian Chai
over 4 years ago
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Which test is used to diagnose asthma?
What is the chemical structure of B2 agonists? How does te long acting one differ from the short acting one structurally?
What is the chemical structure of a glucocorticosteroid?
What are two types of bronchodilators?
What are two examples of muscarinic antagonists?
What are the two types of B2 Agonists, and examples of each?
What are the two mechanisms through which glucocorticoids stop inflammatory cell activation, recruitment, and adhesion?
3 Phases of Asthma
1. Immediate phase
-... after exposure
- bronchospasm due to ...
2. Delayed phase
- ... after
- Due to ....narrowing airways
3. Airway/Bronchial hyperresponsiveness to ANY irritant
- ... after
- combination of ...
Side effects of glucocorticosteroids
What are the 5 types of anti-inflammatory agents?
What are the 4 main reactions in asthma?
What are common side effects of muscarinic antagonists?
What are common side effects of B2 agonists?
Salbutamol: B2 agonist, ... acting
Salmeterol: B2 agonist, ... acting
Fluticasone Propionate: inhaled ...
Montelukast: ...receptor antagonist
Theophylline: Xanthine, inhibit ...
Cromoglycate: Cromone, ...mast cells
Omalizumab: ...
Ipratropium Bromide: Muscarinic antagonist/prevent PNS ...hr
Tiotropium Bromide: Muscarinic antagonist/ prevent PNS ...hr
Leukotriene receptors antagonists work by
How does Omalizumab work?
How do xanthines work? Give an Example of one
How do muscarinic antagonists work?
What do they mainly treat?
How do glucocorticosteroids work?
How do cromones work?
How do B2 agonists work?
1. B agonists binds to B2 receptor on SM
2. G protein attached to receptor disassosiates, activates {{c1::adenylyl cyclase }}
3. {{c2::Cyclic AMP}} made from ATP
Cyclic AMP converted to AMP
4. PKA activated
5. Myosin light chain kinase ...in SM cells
6. Relaxation
In SM, cAMP-->relaxation. What are the different mechanisms of b2 agonists/xanthines?
B2 agonists are administered via...
Asthma/bronchitis affects the ...zone
COPD/Emphysema affects the ... zone
5-LO inhibitors such as Zileuton work by...
