Created by Vicky Reese
over 9 years ago
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Rational Use of Drugs
Therapeutic Range
Steady-State Plasma Drug Concentration
Dosing Regimen
Pharmacokinetics
Plasma Concentration-Time Profile of A Drug
BIOAVAILABILITY
AUC
(area under the plasma concentration versus time curve)
Clearance (CL)
Steady state
Volume of Distribution (V)
Clinical use of Volume of Distribution
Loading Dose
Half-life (t1/2)
Half-life is a major determinant of the ff.
First order kinetics
SATURABLE METABOLISM
Zero-order Kinetics