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Pharmacology quiz using the Independent and Supplementary prescribing text book.

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Independent and Supplementary Prescribing

Question 1 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Pharmacokinetics can be described as ________________________

Select one of the following:

  • how the drug elicits it's effect in the body.

  • how the body handles a drug.

  • the composition of a drug.

  • the way in which a drug should be stored.

Explanation

Question 2 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Drugs may act locally or systemically. Systemically means that the drug must enter ___________________ in order to be delivered to its site of action.

Select one of the following:

  • the brain

  • the circulation

  • the lymph nodes

  • the heart

Explanation

Question 3 of 24

1

Which equation can you use to calculate the amount of a drug that reaches the systemic circulation?

Select one of the following:

  • F x dose

  • F/dose

  • F - dose

  • F + (2 x dose)

Explanation

Question 4 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Drugs administered as an IV injection have a bioavailability of _________.

Select one of the following:

  • 100

  • 10

  • 1.0

  • 0.1

Explanation

Question 5 of 24

1

What words make up the acronym ADME?

Select one or more of the following:

  • Administration

  • Absorption

  • Distribution

  • Dissolving

  • Making

  • Metabolism

  • Exit

  • Excretion

Explanation

Question 6 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Generally in absorption, drugs move from an area of high concentration to a low concentration via ______________

Select one of the following:

  • osmosis.

  • active transport.

  • passive diffusion.

Explanation

Question 7 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

When drugs are being absorbed from an area of their low concentration to a higher concentration, they move by _____________

Select one of the following:

  • active transport.

  • osmosis.

  • passive diffusion.

Explanation

Question 8 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Cell membranes are composed of a double layer of ____________________

Select one of the following:

  • proteins.

  • sugars.

  • phospholipids.

  • ions.

Explanation

Question 9 of 24

1

Water soluble drugs pass cell membranes easier than lipid soluble drugs.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

The more _______________ a drug, the easier it is for the drug to be absorbed from the small intestine into the circulation.

Select one of the following:

  • lipid soluble

  • water soluble

Explanation

Question 11 of 24

1

Un-ionised drugs are lipid soluble.

What does un-ionised mean?

Select one of the following:

  • The drug carries no charge.

  • The drug is negatively charged.

  • The drug is positively charged.

  • The molecule contains two opposing charges.

Explanation

Question 12 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

The small intestine has a large surface area due to it's large number of __________.

Select one of the following:

  • villi

  • cillia

  • hairs

  • cells

Explanation

Question 13 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

The larger the surface area for drug absorption, the _______ the absorption.

Select one of the following:

  • slower

  • quicker

Explanation

Question 14 of 24

1

Where does most drug absorption take place?

Select one of the following:

  • Stomach

  • Small Intestine

  • Large Intestine

  • Colon

Explanation

Question 15 of 24

1

The presence of food after a meal will slow gastric emptying.

Select one of the following:

  • True
  • False

Explanation

Question 16 of 24

1

Sometimes drugs are prescribed to be taken with food. Why might this be?

Select one or more of the following:

  • To lessen the side effects of a drug by preventing large concentrations from entering systemic circulation at the same time, ensuring a more gradual absorption due to gastric emptying.

  • To mask the bad taste of a drug that is taken orally.

  • To prevent local side effects, like irritation of the stomach lining, caused by drugs like NSAIDs.

Explanation

Question 17 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Some drugs are absorbed from the small intestine into the _____________ and are transported directly into the liver.

Select one of the following:

  • renal portal vein

  • cranial portal vein

  • hepatic portal vein

Explanation

Question 18 of 24

1

What is the name of the process by which a drug is fully or partially metabolised by the liver, before entering the systemic circulation?

Select one of the following:

  • First pass metabolism

  • Liver/drug degradation

  • First past metabolism

Explanation

Question 19 of 24

1

Hypomotility of the GI tract may result in lower concentrations of drug entering the circulation.

Select one of the following:

  • True
  • False

Explanation

Question 20 of 24

1

Blood flow affects absorption.

Select one of the following:

  • True
  • False

Explanation

Question 21 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

A drug must reach it's site of action in ______________, in order to exert it's effect.

Select one of the following:

  • an adequate concentration

  • a membrane bound vesicle

  • a salt solution

Explanation

Question 22 of 24

1

Blood flow affects distribution.

Select one of the following:

  • True
  • False

Explanation

Question 23 of 24

1

Blood flow affects distribution. Organs that have high perfusion, e.g. heart, therefore receive drugs slowly.

Select one of the following:

  • True
  • False

Explanation

Question 24 of 24

1

Choose the word or phrase from the list below that best completes this sentence.

Only ________ drug can cross plasma membranes and therefore exert an effect.

Select one of the following:

  • free

  • plasma protein bound

  • albumin bound

Explanation

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