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biochem-1

biochem-1

Question 1 of 10

1

Process used in an expression vector to increase yield of recombinant protein synthesis ?

Select one of the following:

  • Translation initiation

  • Promoter induction

  • Transcription terminators

  • Multiple cloning sites

Explanation

Question 2 of 10

1

Rothera’s test is utilised for detection of?

Select one of the following:

  • Glucose

  • Proteins

  • Urea

  • Ketone bodies

Explanation

Question 3 of 10

1

Decreased energy production in thiamine deficiency is due to?

Select one of the following:

  • It is a cofactor for oxidative reduction

  • It is required for transamination reactions

  • It is a coenzyme for alpha ketoglutarate dehydrogenase and pyruvate dehydrogenase in citric acid cycle

  • It is a coenzyme for transketolase in hexose monophosphate shunt

Explanation

Question 4 of 10

1

Which of the following enzymes is responsible for the transfer of amino groups from an amino acid to an alpha keto acid?

Select one of the following:

  • Transaminase

  • Transketolase

  • Deaminase

  • Lyase

Explanation

Question 5 of 10

1

Site of urea cycle is?

Select one of the following:

  • Liver

  • Kidney

  • GIT

  • Lungs

Explanation

Question 6 of 10

1

Which of the following is not a protein misfolding disorder?

Select one of the following:

  • Tuberculosis

  • Creutzfeldt Jakob disease

  • Alzheimer’s disease

  • Cystic fibrosis

Explanation

Question 7 of 10

1

Sphingomyelinase deficiency is characteristic of ?

Select one of the following:

  • Fabry disease

  • Krabbe’s disease

  • Tay Sachs disease

  • Niemann Pick disease

Explanation

Question 8 of 10

1

Xeroderma pigmentosum is produced as a result of a defect in :

Select one of the following:

  • DNA polymerase III

  • DNA exonuclease

  • DNA ligase

  • none

Explanation

Question 9 of 10

1

A genetic disorder renders fructose 1,6 — biphosphatase in liver less sensitive to regulation by fructose 2,6 — bi-phosphate. All of the following metabolic changes are observed in this disorder except:

Select one of the following:

  • Level of fructose 1,6—biphosphate is higher than normal

  • Level of fructose 1,6 — biphosphate is lower than normal

  • Less pyruvate is formed

  • Less ATP is generated

Explanation

Question 10 of 10

1

Alpha helix and Beta pleated sheet are examples of:

Select one of the following:

  • Primary structure

  • Secondary structure

  • Tertiary structure

  • Quaternary structure

Explanation

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