What type of cells form bone?
Osteoblasts
Osteoclasts
What type of cells resorb bone?
Osteocytes are trapped osteoblasts that maintain the bone matrix.
Immature bone that has a random collagenous structure is known as what?
Woven bone
Lamellar bone
Compact bone
Mature bone is known as what?
Cancellous (spongy) bone contains haversian canals.
What is the main component of enamel?
Calcium hydroxyapatite
Magnesium hydroxyapatite
Dentine
Calcium
Dentine is innervated and can repair itself.
Dental pulp contains post natal stem cells.
Fluoride substitution in calcium hydroxyapatite promotes caries.
Carbonate substitution in calcium hydroxyapatite promotes caries.
What inorganic component does bone have?
Carbonated hydroxyapatite
What type of collagen do dentine, cementum and enamel all share?
Type 1
Type 7
Type 4
Type 3
Odontoblasts perform what function?
Produce dentine
Produce enamel
Produce cementum
Cementoblasts perform what function?
Ameloblasts perform what function?
Matrix vesicle mineralisation occurs how?
Vesicles accumulate Ca2+ and P -> Internal surface mineralisation -> Rupturing (release of crystal) -> accumulation
Acid phosphoproteins bind to collagen -> promote crystal growth (scaffold)
Heterogenous nucleation mineralisation occurs how?
How does mineralisation in enamel occur?
Ameloblasts which secrete a matrix that acts as a scaffold
Odontoblasts which secrete a matrix that acts as a scaffold
Osteoporosis is when...
Bone loss > Bone deposition
Bone deposition > bone loss
What bone forms in a fracture site?
Woven
Lamellar
Cancellous
Compact
Fluorosis is characterised by...
High resistance to caries
Hypomineralised enamel
Rapid deciduous tooth loss in children
Osteogenesis imperfecta is caused by a mutation in type 1 collagen.
Dentinogenesis imperfecta leads to hypomineralised enamel.
Amelogenesis imperfecta leads to hypomineralised enamel.
Dense connective tissue is found where?
Tendons
Ligaments
Areolar tissue
Adipose tissue
Loose connective tissue is found where?
Reticular tissue
What is the function of fibroblasts?
Produces collagen
Produces cartilage
What is the function of chondrocytes?
Produce collagen
Produce cartilage
ECM is typically composed of what substances?
Collagen
Elastin
Ground substance
Proteoglycans
A meshwork collagen arrangement takes what sort of load?
Compressional
Stretch
A longitudinal collagen arrangement is for?
Compression
Ground substance is mostly composed of what?
Water
Glycoproteins
Cartilage
What is hyaluronic acid and what is its function?
A proteoglycan
A glycoprotein
Secretes water
Stores water
What is chondroitin sulphate and what is its function?
Offers compressional resistance in cartilage
Gives flexibility in cartilage