Which of the following tissues contain insulin receptor?
Neurons
Skeletal myocytes
Adipocytes
Hepatocytes
None of these
When insulin binds to its receptor, it stimulates the translocation of _____________ - containing vesicles from the ____________ to the plasma membrane.
GLUT1; early endosome
GLUT3; active zone
GLUT4; recycling endosome
GLUT5; late endosome
Insulin stimulates the translocation of glucose permeases, leading to their insertion into the plasma membrane, in which tissues?
Musle
White Adipose
Almost all protein synthesis begins here.
On ribosomes
In the nucleus
In the nucleoulus
In the smooth ER
Which of the following organelles are involved in the biosynthetic pathway?
The ER
Golgi
Secretory Vesicles
Early endosome
Which of the following organelles is a part of the endocytic pathway?
The plasma membrane
Late endosome
Which of the following coat proteins is a part of the retrieval pathway?
COPI
COPII
Clathrin
COPI and COPII only
Formation of a clathrin-coated vesicle requires which of the following?
Caveoilins
Adaptor proteins
ARF 1
Dynamin
None of these.
In which organelle is ceramide synthesized?
rER
sER
Endosome
Which of the following statements about glycolipids and sphingomyelins are true?
Both are synthesized from ceramide.
Both contain saccharides.
Glycolipids are synthesized in the sER whereas sphingomyelins are synthesized in the golgi.
Both contain a glycerol molecule.
None of these is correct.
Which of the following is a means by which the cell tags and targets proteins for inclusion in transport vesicles?
Specific amino acid sequences
Oligosaccharide modifications
Hydrophobic domains
How is calcium transported into the sER?
Facilitated diffusion
Ligand-gated channel
Direct active transport
How is calcium transported into a cell (across the plasma membrane)?
Passive diffusion
Which of the following is correctly arranged in order of INCREASING pH (i.e. from acid to alkaline)?
Lysosome, cytosol, early endosome, late endosome
Cytosol, synaptic vesicle, recycling endosome, ER
Late endosome, early endosome, lysosome, cytosol
Proteins targeted to the lysosome contain a __________________ tag.
KDEL
Mannose-6-P
Phosphatidylinositol
SAR-1