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Infection and Immunity Quiz on The Adaptive Immune System , created by m p on 15/06/2015.

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The Adaptive Immune System

Question 1 of 35

1

What triggers the activation of the adaptive immune system?

Select one of the following:

  • Pathogen exposure

  • Inflammation

  • Antibody production

  • Phagocytosis

Explanation

Question 2 of 35

1

There are two components of the adaptive immune system. What are they called?

Select one or more of the following:

  • Cellular immune system

  • Humoral immune system

  • Antigenic immune system

  • Cytotoxic immune system

  • Acquired immune system

Explanation

Question 3 of 35

1

What happens to the response of the immune system on each repeated exposure to a pathogen?

Select one or more of the following:

  • It becomes faster

  • It becomes more specific

  • It causes more inflammation

  • It becomes less efficient

  • It involves more components of the immune system

Explanation

Question 4 of 35

1

What cells are involved in humoral immunity?

Select one of the following:

  • B cells

  • T cells

  • Natural killer cells

  • Phagocytes

Explanation

Question 5 of 35

1

What cells are involved in cellular immunity?

Select one of the following:

  • B cells

  • T cells

  • Phagocytes

  • Natural killer cells

Explanation

Question 6 of 35

1

Which part of the adaptive immune system produced antibodies?

Select one of the following:

  • Humoral

  • Cellular

  • Both

Explanation

Question 7 of 35

1

The adaptive immune system is able to remember pathogens in case they present again. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 8 of 35

1

Which cells express CD4?

Select one of the following:

  • T helper cells

  • T killer cells

  • T regulatory cells

  • Plasma B cells

Explanation

Question 9 of 35

1

What is the function of T helper cells?

Select one or more of the following:

  • Activate macrophages

  • Help B cells to produce antibodies

  • Remember the pathogen in case of repeat infection

  • Produce antibodies

  • Activate natural killer cells

Explanation

Question 10 of 35

1

Why do we need T regulatory cells?

Select one of the following:

  • To control the immune response

  • To ensure the immune response is specific

  • To prevent the immune system from attacking healthy cells

  • To prevent the immune system from attacking normal flora

Explanation

Question 11 of 35

1

Which cells expressed CD8?

Select one of the following:

  • T killer cells

  • T helper cells

  • T regulatory cells

  • Plasma B cells

Explanation

Question 12 of 35

1

Which cells have the longest life-span?

Select one of the following:

  • T regulatory cells

  • Memory B cells

  • Plasma B cells

  • T helper cells

Explanation

Question 13 of 35

1

How are antibodies separated into classes?

Select one of the following:

  • By their heavy chain

  • By their light chain

  • By their constant region

  • By their variable region

  • By what sort of pathogen they are against

Explanation

Question 14 of 35

1

What is the function of membrane bound antibodies?

Select one or more of the following:

  • Recognise antigens

  • Activate B cells

  • Activate T cells

  • Opsonisation

  • Neutralization of pathogens

Explanation

Question 15 of 35

1

Which type of antibody activates complement?

Select one of the following:

  • Membrane bound antibodies

  • Secreted antibodies

Explanation

Question 16 of 35

1

Which cells require an antigen presenting cell to activate them?

Select one of the following:

  • T cells

  • B cells

Explanation

Question 17 of 35

1

Which of the following cells can act as antigen presenting cells?

Select one or more of the following:

  • Dendritic cells

  • Macrophages

  • Natural killer cells

  • Plasma B cells

  • Mast cells

Explanation

Question 18 of 35

1

Which cells express MHCI?

Select one of the following:

  • All nucleated cells

  • T helper cells

  • Antigen presenting cells

  • Plasma B cells

  • Natural killer cells

Explanation

Question 19 of 35

1

Which of the following cells recognised MHCII?

Select one of the following:

  • CD8 cells

  • CD4 cells

Explanation

Question 20 of 35

1

Where within the antigen presenting cell is the MHC produced?

Select one of the following:

  • Endoplasmic reticulum

  • Golgi body

  • Ribosome

  • Nucleus

Explanation

Question 21 of 35

1

Where is the MCHII complex combined with the antigenic peptides?

Select one of the following:

  • Endosome

  • Endoplasmic reticulum

  • Golgi body

  • Vesicle

Explanation

Question 22 of 35

1

The T cell is activated when it detects the MHC-antigen complex. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 23 of 35

1

Which types of hypersensitivity reaction are mediated by antibodies?

Select one or more of the following:

  • I

  • II

  • III

  • IV

Explanation

Question 24 of 35

1

Which type of hypersensitivity reaction is mediated by IgE?

Select one of the following:

  • I

  • II

  • III

  • IV

Explanation

Question 25 of 35

1

Which of the following are examples of hypersensitivity reactions that are mediated by IgE?

Select one or more of the following:

  • Asthma

  • Pollen allergy

  • SLE

  • Myasthenia Gravis

  • Grave's disease

  • Type I diabetes

  • Psoriasis

Explanation

Question 26 of 35

1

In a type I hypersensitivity reaction, what needs to happen to the antibodies on repeat exposure for there to be a hypersensitivity reaction?

Select one of the following:

  • Clonal expansion

  • Cross-linking

  • Breaking of the disulphide bonds

  • Dimer formation

Explanation

Question 27 of 35

1

Grave's disease is an example of a type II hypersensitivity reaction. What are type II hypersensitivity reactions mediated by?

Select one of the following:

  • IgE

  • Antibodies other than IgE

  • T helper cells

  • T cytotoxic cells

  • Natural killer cells

Explanation

Question 28 of 35

1

What is another example of a type II hypersensitivity reaction?

Select one of the following:

  • Myasthenia Gravis

  • Asthma

  • Type I diabetes

  • SLE

  • Coeliac disease

Explanation

Question 29 of 35

1

How do the antibodies in type II hypersensitivity reactions cause disease?

Select one or more of the following:

  • They block the receptor

  • They activate the receptor

  • They destroy the receptor

  • They act as inverse agonists

Explanation

Question 30 of 35

1

In which type of hypersensitivity reaction after immune complexes formed?

Select one of the following:

  • I

  • II

  • III

  • IV

Explanation

Question 31 of 35

1

Why are immune complexes a problem?

Select one of the following:

  • Because they can get stuck in the body

  • Because they promote autoimmune destruction of cells

  • Because they promote other hypersensitivity reactions

  • Because they increase the viscosity of blood which can cause thrombosis

  • Because they cause lymphadenopathy

Explanation

Question 32 of 35

1

Antibodies in immune complexes can activate complement. True or false?

Select one of the following:

  • True
  • False

Explanation

Question 33 of 35

1

What are type IV hypersensitivity reactions mediated by?

Select one of the following:

  • T helper cells

  • Antibodies other than IgE

  • IgE

  • T killer cells

Explanation

Question 34 of 35

1

Which of the following are examples of type IV hypersensitivity reactions?

Select one or more of the following:

  • Coeliac disease

  • Type I diabetes

  • SLE

  • Asthma

  • Haemolytic disease of the new born

Explanation

Question 35 of 35

1

How do T helper cell cause hypersensitivity reactions?

Select one of the following:

  • Cytokine production that activates macrophages and T cytotoxic cells

  • Activation of natural killer cells

  • Activation of mast cells causing release of histamine

  • Formation of immune complexes which activate complement

Explanation

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