Pharmacology VII (100 Flash Cards)

Aplastic anemia is a toxic effect that occurs after a course of tx with which antibiotic?

side effect of prolonged tetracycline hydrochloride therapy??

colitis that results following clindamycin therapy is caused by an overgrowth of

a. C. difficile
b. staph aureus
c. pseudomonas
d. candida albicans

which antibiotic is appropriate for premed in penicillin allergic patient?

Acycolvir used to treat what?

Advantage that tetracyclines have over penicillins is that they...

Which of the following has the broadest antimicrobial spectrum?
a. vancomycin
b. clindamycin
c. erythromycin
d. chlorotetracycline
e. a third gen cephlosporin

Sulfanomides & Trimethoprim are synergistic bacteriostatic agents bc they both...

Most effective against fungal infections of the mucous membrane?

most desirable property of antibiotic when used to treat odontogenic infection is?

Which drug chelates with calcium?

Which is NOT a characteristic of tetracycline?

Concurrent admin of PenG and probenecid results in?

interaction between penicillin and probenicid is best described by?

when broad spec antibiotics are administered with COUMARIN anticoagulants, the coumarin action may be...

therapeutic effectiveness of which drug will be most affected by ingestion of antacids?

erythromycin should be avoided in the patient taking

a. aspirin
b. seldane
c. benadryl
d. ibuprofen
e. propranolol

Quinidine is primarily used to treat...

Quinidine is used to treat...

Verapamil is most effecacious in tx of ...

Most useful drug in treatment of prevention of angina pectoris?

each of the following drugs can be used in prevention of tx of angina pectoris EXCEPT...
a. digitalis
b. propanolol
c. nitroglycerin
d. isosorbidide dinitrate

all of the following drugs are useful in the tx of hypertension EXCEPT
a. ephedrine
b. reserpine
c. methyldopa
d. thiazide diuretics

DIGITALIS is useful in tx of which condition?
a. AFib
b. congestive heart failure
c. paroxysmal atrial tachycardia
d. all of the above

all of the following drugs are useful in tx of cardiac arrythmias EXCEPT
a. digitalis
b. lidocaine
c. phenytoin
d. procainamide
e. aminophylline

drug of choice for initial therapy of MILD hypertension?

which antihypertensive reserved for SEVERE hypertension?

which B-adrenergic receptor blocking agents is thought to be cardioselective?

antiarrthymic drugs, like quinodine, suppress certain cardiac arrhythmias by ...

most important pharmocological action of drugs that suppress cardiac arrhythimias is ...

lidocaine produces its antiarrythmic effects by

a. increasing AV conduction
b. decreasing cardiac excitability
c. increasing cardiac conduction velocity
d increasing spontaneous pacemaker activity

When digitalis is used in AFib, the therapeutic objective is to ...

Nitroglycerine dilates the coronary arteries in angina pectoris by ...

Propanolol is value in treating angina pectoris bc it...

Primary antihypertensive effect of captopril is due to accumulation of what?

Which of the folllowing is NOT characteristic of thiazide diuretics?

Which of the following drugs act by inhibiting renal reabsorption of Na+?

digoxin exerts its positive inotropic effect by

a. activation of adenylcyclase
b. inhibition of phosphodiesterase
c. an agonist effect of beta-receptors
d. inhibition of Na, K ATPase leading to increased calcium influx
e. decreasing the amount of calcium made available for excitation-contraction coupling

digitoxin is effective in tx of cardiac failure because it

primary action of therapeutic dose of digitalis on cardiac muscle is an increase in what?

the cardiac glycosides will increase the concentration of which ion in an active heart muscle?

Which of the follow ions augments the concentration of which ion in active heart muscle?

The tx of congestive heart failure, digitalis glycosides generally decrease all of the following except?
a. edema
b. urine flow
c. heart size
d. heart rate
e. residual diastolic volume

The mechanism of action of prazosin, an antihypertensive agent is to...

which of the following owes a significant amt of its antihypertensive effect to a CENTRAL ACTION?

Which drugs is thought to reduce arterial blood pressure by activating alpha receptors in the vasomotor center of medulla?

Propanolol can be used in tx of hypertension because it blocks what?

one of the proposed mechanism of the antihypertensive effect of beta adrenergic receptor blocking agents is?

Selective beta 1 AGONISTS will produce what effects?

ototoxicity with deafness may be encountered occasionally in patients taking which of the following diuretic agents?

a. osmotic
b. thiazide
c. mercurial
d. high-cieling

symptoms of digitalis toxicity include all of the following EXCEPT

a. extrasystoles
b. nausea and vomiting
c. yellow-green vision
d. A-V conduction block
e. decreased P-R interval

admin of which of the following drugs increases the likelihood of toxic response to digitalis?

therapeutic effect of salicylates?

mechanism of the antipyretic action of salicyclates results from?

antipyretic action of salicyclates is explained in part by?

the locus of action of aspirin's central antipyretic effect is the

a. brain stem
b. hypothalamus
c. basal ganglia
d. limbic system
e. cerebram cortex

patient who has been taking large quantities of aspirin might show increased post op bleeding because aspirin inhibits what?

anti-inflammatory agents like aspirin interefere with hemostasis by

which of the following anti-inflammatory agents does NOT act primarily by inhibiting activity of prostaglandin synthetase?

a non-steroidal, anti-inflammatory agent that appears to produce fewer GI disturbance than high doses of aspirin?

prolonged use of which of the following drugs does NOT cause a predisposition to gastric irritation and bleeding?

a. phenytoin
b. ibuprofen
c. idomethacin
d. phenylbutazone
e. acetylsalicylic acid

each of the following agents has been associated with GI irritation except?
a. aspirin
b. alcohol
c. ibuprofen
d. indomethacin
e. acetaminophen

which is not produced by excessive doses of acetylsalicylic acid?
a. delirium
b. tinnitus
c. hypothermia
d. hyperventilation
e. metabolic acidosis

all of the following are pharmacologic and toxicologic properties of aspirin except?
a. tinnitus
b. analgesia
c. salicyclism
d. antipyresis
e. suppression of immune response

T/F: acetylsalicyclic acid causes methemoglobinemia

aspirin does not cause what?

which is not true of acetaminophen?

most prominent acute toxic effect associated with acetaminophen is

which antiinflammatory agents does not act by inhibiting activity of cyclooxygenase?

which drug to use to lower fever in child under 12?

which analgesic has the longest half life?

least likely characteristic of narcotic ingestion?

morphine administered IM may produce what symptoms?

which drug acts to suppress cough reflex?

morphine binds to which site to produce analgesia?

morphine causes vomiting by...

the decrease in ventilation cause by morphine, meperidine, and other opioids depends on

Pathognomonic symptoms of narcotic overdose?

barbituates and morphine depresses respiration primarly by...

cause of death with opioid intoxication ?

opioid that has both agnostic and antagonistic activities?

A heroin-dependent patient should NOT be given nalbuphine (Nubain) for pain because
a. It has no analgesic properties
b. It may produce respiratory depression
c. As a mixed agonist-antagonist, it can elicit withdrawal
symptoms
d. The high abuse potential of nalbuphine may add to the patient's
problems

patient sober from narcotics for 6 months, which analgesic should be avoided?

antagonist of choice for opioid overdose?

methadone used for detox of patients dependent on morphine because?

widely used in tx of opioid dependent people?

meperedine (demerol) is

atropine and propantheline exert effects on peripheral structures by

Neostigimine produces its effect by

Organophosphates insecticides and nerve gases inhibit action of which enzymes?

drugs which are additive or potentiate effects of AcH include

which drugs is best to administer after poisoning by an organophosphate cholinesterase inhibitor?

antagonizing cholinesterase?

prevent laryngospasm?

to treat xerostomia?

which would create dry secretions in oral cavity?

most useful type of drug to induce saliva?

control excess saliva?

admin of ganglionic blocking agents will result in?

tachycardia in a patient administered with atropine or scopolamine results from

a. release of adrenal catecholamines
b. blockade of vagus nerve activity
c. blockade of the nicotinic cholinergic receptor
d. stimulation of the alpha adrenergic receptor
e. stimulation of the beta adrenergic receptor