This is a timed quiz.
You have 1 hour to complete the 19 questions in this quiz.
Occurrence of which of the following is LEAST characteristic of narcotic ingestion?
A) Vomiting
B) Diarrhea
C) Urinary retention
D) Bronchiolar constriction
E) Increase in intracranial pressure
Therapeutic doses of morphine administered intramuscularly may produce a. Constipation b. Euphoria c. Dysphoria d. Mental clouding e. Decreased response to pain
A) (a) and (b) only
B) (a), (b) and (d)
C) (a), (d) and (e)
D) (c), (d) and (e)
E) All of the above
Which of the following are pharmacologic effects of morphine? a. Respiratory depression b. Euphoria c. Sedation d. Constipation e. Dysphoria
A) (a), (b) and (c)
C) (a) and (e)
Which of the following drugs acts to suppress the cough reflex?
A) ASA
B) Codeine
C) Meperidine
D) Acetaminophen
E) Phenyibutazone
Morphine binds to which site to produce analgesia?
A) By binding to specific receptors in the CNS
B) By decreasing the influx of sodium
C) By decreasing the synthesis of prostaglandins
D) By decreasing nerve activatin at the site of injury
Morphine causes vomiting by
A) A direct irritant action on the gastric mucosa
B) Stimulation of the nodose ganglion of the vagus nerve
C) Stimulation of the medullary chemoreceptor trigger zone
D) Direct stimulation of the gastrointestinal musculature
The decrease in ventilation caused by morphine, meperidine and some of the related opioids depends chiefly upon
A) Depression of cortical activity
B) Peripheral blockade of chemoreceptor impulses
C) An increase in carbon dioxide concentration in the blood
D) Blockade of afferent autonomic impulses from the lungs
E) Loss of sensitivity of the medullary respiratory center to carbon dioxide
Small doses of barbiturates and morphine depress respiration primarily by
A) A parasympathominetic action
B) Inhibiting the Herine-Bueuer reflex
C) Rendering the aortic chemoreceptor system insensitive to O2
D) Rendering the respiratory center in the brain stem less sensitive to changes in CO2
E) A specific effect at myoneural junctions of phrenic and intercostal nerves
Which of the following are pathognomonic symptoms of narcotic overdose?
A) Miosis, coma and depressed respiration
B) Mydriasis, coma and smooth muscle spasms
C) Mydriasis, coma and depressed respiration
D) Miosis, convulsions and depressed respiration
E) Mydriasis, convulsions and depressed respiration
The cause of death with opioid intoxication is
A) Oxygen apnea
B) Cardiac arrest
C) Terminal convulsions
D) Circulatory collapse
E) Respiratory depression
Which of the following is an opioid that has both agonistic and antagonistic activities?
A) Codeine
B) Methadone
C) Naloxone
D) Meperidine
E) Pentazocine
A heroin-dependent patient should NOT be given nalbuphine (Nubain) for pain because
A) It has no analgesic properties
B) It may produce respiratory depression
C) As a mixed agonist-antagonist, it can elicit withdrawal symptoms
D) The high abuse potential of nalbuphine may add to the patient's problems
A patient while not currently taking drugs has a history (6 months ago) of narcotic dependency. Which of the following analgesics should be avoided in this patient?
A) Aspirin
B) Pentazcine
C) propoxyphene
D) Indomethacin
E) Acetaminophen
F) None of the above
Which of the following statements does NOT characterize pentazocine?
A) It is equianalgesic with codeine
B) It is a partial opioid antagonist
C) Its abuse potential is less than that of heroin
D) It may induce dysphoria and mental aberrations
E) It is effective only on parenteral administration
The antagonist of choice in the treatment of opioid overdosage is
A) Naloxone
B) Nalorphine
C) Pentazocine
D) Levallorphan
E) Propoxyphene
Which of the following is a complete antagonist of the opioid receptor and the agent of choice in the treatment of narcotic overdose?
C) Cyclazocine
E) None of the above
Methadone is used in detoxification (drug withdrawal) of patients physically dependent on morphine because methadone
A) Precipitates withdrawal reactions
B) Antagonizes the depressant actions of morphine
C) Will not in itself produce physical dependence
D) Withdrawal reactions are less intense and stressful than those of morphine
Which of the following drugs is currently widely used in treating opioid-dependent individuals?
C) Alphaprodine
D) Pentazocine
E) Meperidine
Meperidine (Demerol) is
A) An antidepressant
B) An opioid analgesic
C) A sedative
D) A long-acting local anesthetic
E) An antipsychotic