Pharmacology III

1

Which of the following is a local anesthetic subject to inactivation by plasma esterases?

1

Procaine differs from lidocaine in that

1

Which of the following local anesthetics would be expected to produce a sensitization reaction in a patient allergic to lidocaine?
a. Mepivacaine
b. Tetracaine
c. Procaine
d. Prilocaine
e. Dibucaine?

1

The hydrolysis of procaine occurs mainly in the

1

Which of the following is local anesthetic subject to inactivation by plasma esterases?

1

The activity of procaine is terminated by

1

All of the following factors are significant determinants of the duration of conduction block with amide-type local anesthetics EXCEPT the

1

Which of the following is contraindicated for a patient who had an allergic reaction to procaine six months ago?

1

Bupivacaine (Marcaine) has all of the following properties relative to lidocaine (Xylocaine) EXCEPT

1

Amide-type local anesthetics are metabolized in the

1

The duration of action of lidocaine would be increased in the presence of which of the following medications?

1

Severe liver disease least affects the biotransformation of which of the following?

1

A patient has been given a large volume of a certain local anesthetic solution and subsequently develops cyanosis with methemoglobinemia. Which of the following drugs most likely was administered?

1

Use of prilocaine carries the risk of which of the following adverse effects?

1

The most probable cause for a serious toxic reaction to a local anesthetic is

1

High plasma levels of local anesthetics may cause

1

Unfortunately, you injected your lidocaine intra-arterially. The first sign of lidocaine toxicity that might be seen in the patient would be

1

The first sign that your patient may be experiencing toxicity from too much epinephrine would be

1

Which disease condition would make the patient most sensitive to the epinephrine in the local anesthetic?

1

Cardiovascular collapse elicited by a high circulating dose of a local anesthetic may be caused by

1

The most serious consequence of systemic local anesthetic toxicity is

1

Hypotensive shock may result from excessive blood levels of each of the following local anesthetics EXCEPT

1

Which of the following anesthetic drugs produces powerful stimulation of the cerebral cortex?

1

Local anesthetics block nerve conduction by

1

Which of the following is true regarding the mechanism of action of local anesthetics?

1

Local anesthetic agents prevent the generation of nerve impulses by

1

Local anesthetics interfere with the transport of which of the following ions during drug-receptor interaction

1

If the pH of an area is lower than normal body pH, the membrane theory of local anesthetic action predicts that the local anesthetic activity would be

1

A local anesthetic injected into an inflamed area will NOT give maximum effects because

1

The penetration of a local anesthetic into nervous tissue is a function of the

1

At a pH of 7.8, lidocaine (pKa = 7.8) will exist in

1

The more rapid onset of action of local anesthetics in small nerves is due to

1

Which of the following statements are true regarding onset, degree and duration of action of local anesthetics?
a. The greater the drug concentration, the faster the onset and the greater the degree of effect
b. Local anesthetics block only myelinated nerve fibers at the nodes of Ranvier
c. The larger the diameter of the nerve fiber, the faster the onset of effect
d. The faster the penetrance of the drug, the faster the onset of effect

1

A dentist administers 1.8 ml of a 2% solution of lidocaine. How many mg of lidocaine did the patient receive?

1

Three ml of a local anesthetic solution consisting of 2% lidocaine with 1:100,000 epinephrine contains how many milligrams of each?

1

The maximum allowable adult dose of mepivacaine is 300 mg. How many milliliters of 2% mepivacaine should be injected to attain the maximal dosage in an adult patient?

1

A recently introduced local anesthetic agent is claimed by the manufacturer to be several times as potent as procaine. The product is available in 0.05% buffered aqueous solution in 1.8 ml. cartridge. The maximum amount recommended for dental anesthesia over a 4-hour period is 30 mg. The amount is contained in approximately how many cartridges?

1

According to AHA guidelines, the maximum # of carpules of local anesthetic containing 1:200,000 epinephrine that can be used in the patient with cardiovascular disease is

Praxis Tests: Pharmacology Quiz on Pharmacology III , created by ACAPUN INSTITUTE on 08/11/2021.

Pharmacology III

Pharmacology III

Which of the following is a local anesthetic subject to inactivation by plasma esterases?

Procaine differs from lidocaine in that

Which of the following local anesthetics would be expected to produce a sensitization reaction in a patient allergic to lidocaine? a. Mepivacaine b. Tetracaine c. Procaine d. Prilocaine e. Dibucaine?

The hydrolysis of procaine occurs mainly in the

Which of the following is local anesthetic subject to inactivation by plasma esterases?

The activity of procaine is terminated by

All of the following factors are significant determinants of the duration of conduction block with amide-type local anesthetics EXCEPT the

Which of the following is contraindicated for a patient who had an allergic reaction to procaine six months ago?

Bupivacaine (Marcaine) has all of the following properties relative to lidocaine (Xylocaine) EXCEPT

Amide-type local anesthetics are metabolized in the

The duration of action of lidocaine would be increased in the presence of which of the following medications?

Severe liver disease least affects the biotransformation of which of the following?

A patient has been given a large volume of a certain local anesthetic solution and subsequently develops cyanosis with methemoglobinemia. Which of the following drugs most likely was administered?

Use of prilocaine carries the risk of which of the following adverse effects?

The most probable cause for a serious toxic reaction to a local anesthetic is

High plasma levels of local anesthetics may cause

Unfortunately, you injected your lidocaine intra-arterially. The first sign of lidocaine toxicity that might be seen in the patient would be

The first sign that your patient may be experiencing toxicity from too much epinephrine would be

Which disease condition would make the patient most sensitive to the epinephrine in the local anesthetic?

Which of the following local anesthetics would be expected to produce a sensitization reaction in a patient allergic to lidocaine?
a. Mepivacaine
b. Tetracaine
c. Procaine
d. Prilocaine
e. Dibucaine?