Esmeralda Espitia
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patho 1 Quiz on Ch. 6 Epigentics, created by Esmeralda Espitia on 04/02/2022.

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Esmeralda Espitia
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Ch. 6 Epigentics

Question 1 of 13

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1. What genetic process is likely responsible for the occurrence of asthma in only one of a pair of identical twins?

Select one of the following:

  • a. Epigenetic modifications

  • b. Genomic imprinting

  • c. Transgenerational inheritance

  • d. Methylation

Explanation

Question 2 of 13

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2. Prader-Willi syndrome causes a chromosomal defect that is what?

Select one of the following:

  • a. Initiated by postnatal exposure to a virus

  • b. Inherited from the father

  • c. Related to maternal alcohol abuse

  • d. Transferred from mother to child

Explanation

Question 3 of 13

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3. What can a malfunction in DNA methylation lead to?

Select one of the following:

  • a. Hypothyroidism

  • b. Blindness

  • c. Cancer

  • d. Diabetes mellitus

Explanation

Question 4 of 13

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4. Which statement is true regarding the embryonic development of stem cells?

Select one of the following:

  • a. They are already differentiated.

  • b. They are referred to as housekeeping genes.

  • c. They already demonstrate DNA sequencing.

  • d. They are said to be totipotent.

Explanation

Question 5 of 13

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5. When microRNA (miRNA) are methylated their messenger RNA (mRNA) targets are over- expressed. What would be the resulting effect on existing cancer?

Select one of the following:

  • a. Cell death

  • b. Metastasis

  • c. Remission

  • d. Relapse

Explanation

Question 6 of 13

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6. What is the difference between DNA sequence mutations and epigenetic modifications?

Select one of the following:

  • a. DNA sequence mutations can be directly altered.

  • b. Leukemia is a result of only DNA sequence mutation.

  • c. Epigenetic modifications potentially can be reversed.

  • d. No known drug therapies are available for epigenetic modifications.

Explanation

Question 7 of 13

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7. Which term refers to the silenced gene of a gene pair?

Select one of the following:

  • a. Activated

  • b. Altered

  • c. Mutated

  • d. Imprinted

Explanation

Question 8 of 13

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8. What is most likely the shape of the face of a child diagnosed with Russell-Silver syndrome?

Select one of the following:

  • a. Round

  • b. Square

  • c. Triangular

  • d. Elongated

Explanation

Question 9 of 13

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9. What are genes responsible for the maintenance of all cells referred to as?

Select one of the following:

  • a. Universal

  • b. Managerial

  • c. Housekeeping

  • d. Executive

Explanation

Question 10 of 13

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10. What is the belief regarding twins who adopt dramatically different lifestyles?

Select one of the following:

  • a. They may experience very different aging processes.

  • b. They will retain very similar methylation patterns.

  • c. They will experience identical phenotypes throughout their lifespans.

  • d. They may never demonstrate similar DNA sequences of their somatic cells.

Explanation

Question 11 of 13

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11. What do hypomethylation and the resulting effect on oncogenes result in?

Select one of the following:

  • a. A decrease in the activity of the oncogene, thus suppressing cancer development.

  • b. A deactivation of MLH1 to halt DNA repair.

  • c. An increase in tumor progression from benign to malignant.

  • d. An over-expression of microRNA, resulting in tumorigenesis.

Explanation

Question 12 of 13

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12. When a chromosome lacking 4 million base pairs is inherited from the mother, the child is at risk for developing which syndrome?

Select one of the following:

  • a. Prader-Willi

  • b. Angelman

  • c. Beckwith-Wiedemann

  • d. Russell-Silver

Explanation

Question 13 of 13

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2. A diagnosis of Angelman syndrome in a child is supported by which assessment findings?(Select all that apply.)

Select one or more of the following:

  • a. Small feet and hands

  • b. Profound intellectual disability

  • c. Obesity

  • d. Ataxic gait

  • e. History of seizures

Explanation

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