absorption

active pharmaceutical ingredient (API)

adverse effect

alkaloid

allosteric site

alpha-helix (α-helix)

amide linkage

analgesic

analogues

apparent volume of distribution (Vd)

area under curve (AUC)

arsenicals

assay

beta-sheet (β-sheet)

binding energy

bioavailability (F)

bioequivalence testing

bioisosteres

bolus

Caco-2 cells

cell permeability

central compartment

Cheng-Prussoff equation

classical isosteres

clearance (CL)

combinatorial chemistry

compartment model

competitive inhibitor

composition of matter

compound library

concensus scoring

cytochrome P-450 (CYP)

depolarization

desensitization

directed combinatorial chemistry

distribution

distribution phase

docking

downregulation

drug-like

drug product

drug substance

drug-target residence time

elimination

elimination phase

elimination rate constant (kel)

endogenous ligand

enzyme (E)

enzyme-substrate complex (E-S)

excretion