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Biosynthesis of Fatty Acids and synthesis of triglycerides, phosphoglycerides and esfingolipids test

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LESSON 26 & 27

Question 1 of 11

1

Where takes place the biosynthesis of fatty acids?

Select one of the following:

  • In the mitochondrial matrix

  • In the mitochondrial membrane

  • In the cytosol

  • In the reticulum endoplasmatic

  • Any of these

Explanation

Question 2 of 11

1

Which of the next statements is not true?

Select one of the following:

  • AcetylCoA is produced in mitochondria and can not get out by itself

  • AcetylCoA reacts with oxaloacetate forming citrate

  • In the cytosol, citrate is going to be transformed into AcetylCoA and oxaloacetate with an enzyme called citrate lyase

  • Oxaloacetate need to go back to mitochondria and then can participate in lipolysis

  • The tissues where the biosynthesis of Fatty acids takes place are liver, adipose tissue and mammary gland

Explanation

Question 3 of 11

1

Which of these enzymes is regulated during the biosynthesis of fatty acids?

Select one of the following:

  • Citrate lyase

  • AcetylCoA carboxylase

  • Fatty acid synthase

  • Acyl protein carrierase

  • ACP transferase

Explanation

Question 4 of 11

1

Which of these is not true?

Select one of the following:

  • AcetylCoA carboxylase will be active as a polymer

  • Acetyl carboxylase will form a polymer in presence of citrate

  • Acetyl carboxylase will be inactive in presence of Palmitic acid

  • AcetylCoA carboxylase is active when it is phosphorylated

  • In a fed state, acetyl CoA will be active and we will produce MalonylCoA

Explanation

Question 5 of 11

1

Fatty acid synthase can complete biosynthesis of fatty acids by itself

Select one of the following:

  • True
  • False

Explanation

Question 6 of 11

1

Which of these statements is not true?

Select one of the following:

  • Acyl carrier protein has two different SH groups

  • One molecule of AcetylCoA will bind to the enzyme fatty acid synthase

  • One molecule of MalonylCoA will bind to the Acyl carrier protein

  • During the biosynthesis de novo, when a condensation is produce we obtain one molecule of CO2 and a fatty acid with a double bond between α-Carbon and ß-Carbon

  • During the biosynthesis de novo, a translocation of the fatty acid from ACP to the FAD is produced and the process repeats again

Explanation

Question 7 of 11

1

In which step of biosynthesis de novo a molecule of NADPH is required?

Select one of the following:

  • In the condensation

  • In the dehydration

  • In the reduction

  • In the elongation

  • Any of these

Explanation

Question 8 of 11

1

When will finish the biosynthesis of one fatty acid?

Select one of the following:

  • When we obtain a fatty acid with 18C atoms (Palmitic acid)

  • When we obtain a fatty acid with 16C atoms (Palmitic acid)

  • When we obtain linoleate

  • When we obtain α-linoleate

  • When a double bound in a position higher than 9 is produced

Explanation

Question 9 of 11

1

For humans is impossible to introduce a double bond in a fatty acid in a position lower than Carbon nº9

Select one of the following:

  • True
  • False

Explanation

Question 10 of 11

1

Which of these statements about the synthesis of phosphoglycerides is true?

Select one of the following:

  • If the phosphoglyceride does not have Nitrogen, phosphatidic acid is going to react with CTP obtaining CDP-DAG

  • If the phosphoglyceride does not have Nitrogen, phosphatidic acid will be transformed to diacylglycerol

  • If the phosphoglyceride does not have Nitrogen, phosphatidic acid is going to react with CTP obtaining diacylglycerol

  • If the phosphoglyceride does not have Nitrogen, phosphatidic acid will be transformed to diacylglycerol and then is going to react with CTP obtaining CDP-DAG

  • The combination of the non-polar molecule activated will react forming the phosphoglyceride

Explanation

Question 11 of 11

1

CTP is the activator of the synthesis of phosphoglycerides

Select one of the following:

  • True
  • False

Explanation

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