gina_evans0312
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Year 2 Quiz on Genetic Mapping, created by gina_evans0312 on 26/12/2013.

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Genetic Mapping

Question 1 of 19

1

What does genetic mapping rely on?

Select one or more of the following:

  • Inheritence phenotypes

  • Polymorphic Markers

Explanation

Question 2 of 19

1

How is the tracing of inheritence phenotypes done?

Select one of the following:

  • Genetic markers i.e. SNP's

  • Allele complimentation

  • Meiotic Tests

Explanation

Question 3 of 19

1

1cM =

Select one or more of the following:

  • 1% recombination

  • 10% recombination

  • 1kB

  • 10kB

Explanation

Question 4 of 19

1

How are physical maps made?

Select one of the following:

  • Design markers that overlap along the genome

  • Orientation of homologous chromosomes

  • Allele studies

Explanation

Question 5 of 19

1

Physical maps must be made of physically isolated parts of the genome

Select one of the following:

  • True
  • False

Explanation

Question 6 of 19

1

A genetic marker acts as a reference point in a linkage study

Select one of the following:

  • True
  • False

Explanation

Question 7 of 19

1

Genes are usually used as markers in non-human studies. Why can they not be used in humans?

Select one of the following:

  • Human genes are more unstable

  • Human genes vary too much

  • Human genes are more highly conserved

Explanation

Question 8 of 19

1

What is the preferred form of marker in humans?

Select one of the following:

  • Polymorphic introns

  • Polymorphic Exons

  • SNP's

Explanation

Question 9 of 19

1

More polymorphic DNA= less useful

Select one of the following:

  • True
  • False

Explanation

Question 10 of 19

1

Homozygotes are more useful in genetic mapping than heterozygotes

Select one of the following:

  • True
  • False

Explanation

Question 11 of 19

1

How must markers be placed along the chromosome?

Select one or more of the following:

  • Evenly spaced

  • As lightly as possibly

  • As densely as possible

Explanation

Question 12 of 19

1

The aim it to combine genetic and physical maps

Select one of the following:

  • True
  • False

Explanation

Question 13 of 19

1

Once you have a marker with a high linkage to a disease/trait, how do you use the physical map?

Select one of the following:

  • Find the marker and look for genes very close to it

  • Find the suspect gene and look for markers very close to it

  • Find the marker and look for genes as far away as possible

Explanation

Question 14 of 19

1

Which of the following are evenly distributed?

Select one or more of the following:

  • SNP's

  • Minisatellites

  • Microsatellites

  • RFLP's

Explanation

Question 15 of 19

1

Microsatellites are highly polymorphic

Select one of the following:

  • True
  • False

Explanation

Question 16 of 19

1

Which of the following are most useful as markers?

Select one or more of the following:

  • RFLP's

  • Minisatellites

  • Microsetellites

  • SNP's

Explanation

Question 17 of 19

1

There are two alleles (usually) for RFLP's

Select one of the following:

  • True
  • False

Explanation

Question 18 of 19

1

How are minisatellites typed?

Select one of the following:

  • Southern Hybridisation

  • Gel Electrophoresis

  • PCR

Explanation

Question 19 of 19

1

There are more than 10^10 SNP's in the human genome

Select one of the following:

  • True
  • False

Explanation

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