Intro to virology

Question 1 of 31

1

The outer surface of the capsid mediates with host cells.

Select one of the following:

Naked Virus
Enveloped Virus

Explanation

Question 2 of 31

1

The glycoproteins anchored in the envelope and pointing out mediate contact with the host cells.

Select one of the following:

Naked Virus
Enveloped Virus

Explanation

Question 3 of 31

1

Which type of virus is especially Sensitive to lipid solvents (ex. Chloroform, ether) and also to non-ionic detergents.

Select one of the following:

Naked Viruses
Enveloped Viruses

Explanation

Question 4 of 31

1

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( Naked, Enveloped ) viruses tend to be more stable to environmental changes than ( Naked, Enveloped ) viruses.

Explanation

Question 5 of 31

1

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( Naked, Enveloped ) viruses are usually transmitted via aqueous environment: e.g. various body secretions, blood

Explanation

Question 6 of 31

1

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( Naked, Enveloped ) viruses may be transmitted by many routes: e.g. secretions/blood, oral-fecal, skin contact

Explanation

Question 7 of 31

1

What viral structure is defined as a lipid bilayer derived from host cell membranes during the process of virus maturation.

Select one of the following:

Virion
Capsid
Envelope
Nucleocapsid

Explanation

Question 8 of 31

1

Which viral structure is defined as a protein shell that surrounds and protects the viral genome?

Select one of the following:

Virion
Capsomer
Nucleocapsid
Envelope
Cell wall
Capsid

Explanation

Question 9 of 31

1

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( Icosahedral, Helical ) structures approximate spheres.

Explanation

Question 10 of 31

1

Icosahedral structures can have which of the following axis/axes of symmetry? (Select all that apply)

Select one or more of the following:

none. Icosahedral is not symmetrical.
two-fold
three-fold
four-fold
five-fold

Explanation

Question 11 of 31

1

Helical structures can have which of the following axis/axes of symmetry? (Select all that apply)

Select one or more of the following:

None. Helical structures are not symmetrical.
two-fold
three-fold
four-fold
five-fold

Explanation

Question 12 of 31

1

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The Corona family of viruses is classified as
- ( Enveloped, Naked )
-( RNA, DNA ) virus
-with ( helical, icosahedral ) symmetry of the capsid. -It has a ( positive, negative ), ( single-stranded, double stranded ), ( non-segmented, 10-18 segment, 3 Segment, 8 Segment, 2 Segment, 2 copies ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 16-21, 22-27, 8, 7.2-8.4, 10, 12, 3.5-9, 12.7, 13-16, 13.5-21, 13.6, 16-20, 10-14 ) kb.

Explanation

Question 13 of 31

1

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The Reo family of viruses is classified as
-( Naked, Enveloped )
-( RNA, DNA ) virus
-with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( double-stranded, single-stranded ), ( 10-18 segment, non-segmented, 2 copies, 3 segment, 8 segment, 2 segment ) genome.
-It is virion polymerase ( positive., negative. )
-It's genome size is ( 22-27, 8, 7.2-8.4, 10, 12, 3.5-9, 16-21, 12.7, 13-16, 16-20, 10-14 ) total in kb.

Explanation

Question 14 of 31

1

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The Calici family of viruses is classified as a:
-( Naked, Enveloped )
-( RNA, DNA ) virus
-with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) single-stranded, non-segmented, double-stranded, 10-18 segment, (+) single-stranded, 2 copies, (-) single-stranded, non-segmented, (-) single stranded, 3 segment, (-) single stranded, 8 segment, (-) single-stranded, 2 segment ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 8, 22-27, 7.2-8.4, 10, 12, 3.5-9, 16-21, 12.7, 13-16, 13.5-21, 13.6, 16-20, 10-14 ) total in kb.

Explanation

Question 15 of 31

1

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The Picorna family of viruses is classified as a:
-( Naked RNA, Naked DNA, Enveloped RNA, Enveloped DNA ) virus with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) single-stranded, non-segmented, double-stranded, 10-18 segment, (+) single-stranded, 2 copies, (-) single-stranded, non-segmented, (-) single-stranded, 3 segment, (-) single stranded, 8 segment, (-) single stranded, 2 segment ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 7.2-8.4, 22-27, 3.5-9, 13.5-21, 8 ) total in kb.

Explanation

Question 16 of 31

1

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The Flavi family of viruses is classified as a(n):
-( Enveloped RNA, Enveloped DNA, Naked DNA, Naked RNA ) virus with ( Icosahedral, Helical ) symmetry of the capsid.
-It has a ( (+) ss continuous, (-) ss continuous, (-) ss, 3 segment, (-) ss, 8 segment, (-) ss, 2 segment, DS, 10-18 segment, (+) ss, 2 copies ) genome.
-It is virion polymerase ( negative, positive ).
-It's genome size is ( 10, 12, 8, 13-16, 13.5-21, 13.6 ) total in kb.

Explanation

Question 17 of 31

1

The Toga family of viruses is classified as a(n):
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (-) ss continuous genome.
-It is virion polymerase negative.

Select one of the following:

True
False

Explanation

Question 18 of 31

1

Which family of viruses has the following characteristics?
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (+) ss 2 copies genome architecture.
-It is virion polymerase positve.

Select one of the following:

Retroviruses
Flaviviruses
Togaviruses
Corona viruses
Rhabdoviruses

Explanation

Question 19 of 31

1

Which of the following family of viruses have a (-) single stranded, non-segmented genome architecture? (Select all that apply)

Select one or more of the following:

Reoviruses
Flaviviruses
Togaviruses
Retroviruses
Coronaviruses
Filoviruses
Rhabdoviruses
Paramyxoviruses
Arenaviruses
Bunyaviruses

Explanation

Question 20 of 31

1

Which of the following can the smallest possible genome size?

Select one of the following:

Corona viruses
Rhabdoviruses
Arenaviruses
Flaviviruses
Picornaviruses
Retroviruses

Explanation

Question 21 of 31

1

Adenoviruses is a kind of RNA virus

Select one of the following:

True
False

Explanation

Question 22 of 31

1

Herpes virus, Pox viruses, Togaviruses, and Rhabdoviruses are all enveloped viruses

Select one of the following:

True
False

Explanation

Question 23 of 31

1

Which of the following Naked DNA viruses have a linear genome architecture? (Select all that apply)

Select one or more of the following:

Parvoviruses
Papovaviruses
Adenoviruses
Picornaviruses
Arenaviruses

Explanation

Question 24 of 31

1

Filoviruses do not have virion polymerases.

Select one of the following:

True
False

Explanation

Question 25 of 31

1

The pox virus is a Helical enveloped DNA virus.

Select one of the following:

True
False

Explanation

Question 26 of 31

1

Which of the following does not go with the others?

Select one of the following:

Caliciviruses
Picornaviruses
Flaviviruses
Togaviruses
Retroviruses
Coronaviruses

Explanation

Question 27 of 31

1

The virus life cycle:
1. ❌ - virus ❌ to cellular receptor(s)
2. ❌ - ❌ endocytosis or fusion of viral envelope with cell membrane
3. ❌ - ❌
4. ❌ - ❌
• ❌ transcription
• ❌ translation
• ❌ replication
5. ❌ - depends on type of virus
6. ❌ - ❌ generally release by cell ❌; enveloped viruses release by membrane budding

Drag and drop to complete the text.

Attachment

receptor-mediated

mRNA

protein

nucleic acid

naked viruses

depends on type of virus

depends on entry process

Entry

Uncoating

Release

Assembly

Replication

binding

lysis

Explanation

Question 28 of 31

1

Types of Virus Infection

❌ – infection of a permissive cell: results in virus production, may result in cell death (lytic infection)

❌ – infection of a non- or semi-permissive cell: block to virus production at some step so infection
aborts

❌ – long-lasting virus infection. Can be chronic, latent or slow.

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Acute

Abortive

Persistent

Explanation

Question 29 of 31

1

Persistent infections:
• ❌-low levels of virus produced over a long time, chronic virus production and reinfection of cells

• ❌- virus goes dormant following primary infection, may reactivate infection at subsequent times

• ❌: virus production increases slowly over time

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Chronic

Latent

Slow

Explanation

Question 30 of 31

1

Productive infection- Sequence of events

1. ❌
2. ❌ of viral genes

3. Viral ❌

4. ❌ of virus particles

5. Generally (but not always) ❌ of the host cell

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Virus enters susceptible cells

Replication: Transcription / translation

genome replication occurs

Assembly, maturation, and release

results in death

Explanation

Question 31 of 31

1

Latent Infection: Sequence of events

1.Virus ❌

2. ❌ associated viral genes Viral genes for lytic replication not expressed

3.❌

4. ❌

5. ❌ results in lytic gene expression and production of infectious virus

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enters susceptible cells

Transcription / translation of latency

Maintenance of the viral genome

No progeny virions produced

Reactivation of viral gene expression

	Created by bpasistor almost 9 years ago

Going viral

Intro to virology

Question 1 of 31

The outer surface of the capsid mediates with host cells.

Select one of the following:

Explanation

Question 2 of 31

The glycoproteins anchored in the envelope and pointing out mediate contact with the host cells.

Select one of the following:

Explanation

Question 3 of 31

Which type of virus is especially Sensitive to lipid solvents (ex. Chloroform, ether) and also to non-ionic detergents.

Select one of the following:

Explanation

Question 4 of 31

Select from the dropdown lists to complete the text.

Naked Enveloped( Naked, Enveloped ) viruses tend to be more stable to environmental changes than Naked Enveloped( Naked, Enveloped ) viruses.

Explanation

Question 5 of 31

Select from the dropdown list to complete the text.

Naked Enveloped( Naked, Enveloped ) viruses are usually transmitted via aqueous environment: e.g. various body secretions, blood

Explanation

Question 6 of 31

Select from the dropdown list to complete the text.

Naked Enveloped( Naked, Enveloped ) viruses may be transmitted by many routes: e.g. secretions/blood, oral-fecal, skin contact

Explanation

Question 7 of 31

What viral structure is defined as a lipid bilayer derived from host cell membranes during the process of virus maturation.

Select one of the following:

Explanation

Question 8 of 31

Which viral structure is defined as a protein shell that surrounds and protects the viral genome?

Select one of the following:

Explanation

Question 9 of 31

Select from the dropdown list to complete the text.

Icosahedral Helical( Icosahedral, Helical ) structures approximate spheres.

Explanation

Question 10 of 31

Icosahedral structures can have which of the following axis/axes of symmetry? (Select all that apply)

Select one or more of the following:

Explanation

Question 11 of 31

Helical structures can have which of the following axis/axes of symmetry? (Select all that apply)

Select one or more of the following:

Explanation

Question 12 of 31

Select from the dropdown lists to complete the text.

Explanation

Question 13 of 31

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Explanation

Question 14 of 31

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Explanation

Question 15 of 31

Select from the dropdown lists to complete the text.

Explanation

Question 16 of 31

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Explanation

Question 17 of 31

The Toga family of viruses is classified as a(n): -Enveloped RNA virus with Icosahedral symmetry of the capsid. -It has a (-) ss continuous genome. -It is virion polymerase negative.

Select one of the following:

Explanation

Question 18 of 31

Which family of viruses has the following characteristics? -Enveloped RNA virus with Icosahedral symmetry of the capsid. -It has a (+) ss 2 copies genome architecture. -It is virion polymerase positve.

Select one of the following:

Explanation

Question 19 of 31

Which of the following family of viruses have a (-) single stranded, non-segmented genome architecture? (Select all that apply)

Select one or more of the following:

Explanation

Question 20 of 31

Which of the following can the smallest possible genome size?

Select one of the following:

Explanation

Question 21 of 31

Adenoviruses is a kind of RNA virus

Select one of the following:

( Naked, Enveloped ) viruses tend to be more stable to environmental changes than ( Naked, Enveloped ) viruses.

( Naked, Enveloped ) viruses are usually transmitted via aqueous environment: e.g. various body secretions, blood

( Naked, Enveloped ) viruses may be transmitted by many routes: e.g. secretions/blood, oral-fecal, skin contact

( Icosahedral, Helical ) structures approximate spheres.

The Toga family of viruses is classified as a(n):
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (-) ss continuous genome.
-It is virion polymerase negative.

Which family of viruses has the following characteristics?
-Enveloped RNA virus with Icosahedral symmetry of the capsid.
-It has a (+) ss 2 copies genome architecture.
-It is virion polymerase positve.

Persistent infections:
• ❌-low levels of virus produced over a long time, chronic virus production and reinfection of cells

• ❌- virus goes dormant following primary infection, may reactivate infection at subsequent times

• ❌: virus production increases slowly over time

Productive infection- Sequence of events

1. ❌
2. ❌ of viral genes

3. Viral ❌

4. ❌ of virus particles

5. Generally (but not always) ❌ of the host cell

Latent Infection: Sequence of events

1.Virus ❌

2. ❌ associated viral genes Viral genes for lytic replication not expressed

3.❌

4. ❌

5. ❌ results in lytic gene expression and production of infectious virus