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Alanine , Valine , Leucine and Isoleucine interact in a special way within proteins
The secondary amino(imino) group of proline residues
Having aromatic side chains helps you do what, Name amino acids with them
The importance of Tyrosine in enzymes
What role do Disulfide Groups play in polypeptide structures ?
Which amino have a significant positive charge at ph 7.0
Which amino acids have a R group with a net negative charge
Name a derivative of proline and where they are found
What is Collagen
Name 4 examples of connective tissue
Name an uncommon Amino Acid derived from lysine and where it is found
Name a derivative of lysine found in myosin and say what myosin is
Name a derivative of Glutamate and its use
The derivative of Four lysine residues and its function
What is Circular Dichroism
What are Chromophores and how do they act in the chiral Envronment
What did Anfisens experiment show
What conformation are favored by proteins
How can proteins fold so fast
Two classes of molecular chaperons
What are Heat Shot Proteins and what do they do
What catalyzes interchange or shuffling of s-s bonds
What catalyzes the interconversion of the cic and trans isomers of proline
What is the characteristic of proteins containing proline
What are Amyloidoses and what are they caused by
Name Amyloid diseases
Name some of these diseases
What is Parkinsons disease
What is Huntington's disease
What is Prion ?
Name some Prions Disease
What is Proteostasis
What are the two major classes of proteins
What is Keratin and is it found
Name two anticoagulants
What is the major difference between Plasma and Serum
Name plasma proteins
What are the two types of Immune systemes
How does the Cellular immune system work
How does the Humoral Immune system work
What are Antigens and Antibodies and how do they relate
What is a epiotope and how does it relate to the immune system
How can Proteins High specifity be explained
What are they complementary in
How can we make Glycoproteins and proteoglycans
What are carbohydrates
What are the three classes of carbohydrates
What are Epimeres
What is the actual function of a buffer system such as acetate/acetic acid
What two weak interactions are most important in the formation of a cluster of lipid molecules in an aqueous solution
How many of the 20 common amino acids have rings in their structures and which ones are they
What results from a condensation reaction between two amino acides, such as Glycine and Alanine
What is the average weight of an amino acide
Which amino acid would most likely be found in the interior of a globular protein
Which functional group is used to form Disulfide bonds
Which type of weak interaction is more important for cohesiveness and strength between beta-strands in beta-sheets
What is the highest level of protein structure in human insulin,
Which amino acid would most likely be found in the interior of a globular protein
Protein folding to a native conformation is highly dependent upon what
What are the four main steps of sequencing a protein
There are two main ways of breaking disulfide bonds name them and the resultant residues
Name the four Reagents for fragmenting polypeptide chains and where do they fragment
Name two sequencing methods
What is the difference between the Edman degradation method and the Sanger's method
Describe the Edmans degradation for peptide sequencing
Name the four favorable interactions within a protein
Why is rotation around the C-N bond restricted for planar peptide groups in polypeptide chain
Why are nearly all peptide groups in proteins in trans conformation
What are dihedral angles
Name four functions filled by Carbohydrates
Is it true that L and D glucose have different solubility levels
Most Hexoses in living organisms are L steriomeres
What are Diastereoisomeres
Name the three D aldoses seen in class and say if they have the same level of solubility
Draw the two glucose epimers seen in class
What compound is found in self tanner lotion and how is it made
Draw Ribose, glucose, galactose, Mannose and Fructose
Between Aldehydes, Ketone carbons and Alcohol oxygens which are nucleophilic and which are electrophilic
What are Hemiacetals and Hemiketals and how are they formed
what are six membered oxygen containing rings called and draw three
What are five membered oxygen containing rings called
What can carbohydrates be covalently bonded with ?
Give an example of a dissacharide that is 1. A Ketone 2. A polyhydroxyl aldehyde
How can bonds between carbohydrates be 1. Broken 2. synthesized
Name three 3 common disaccharides
Name important Haxose Derivatives 6 in the course
Glycosidic bonds in carbohydrates are between
In gycosidic linkages which elements are reducing or non reducing
Where in nature can trehalose be found in nature and what disease in humans could it be used to treat
Name two oligosaccharides that are components of antibiotics
Natural carbohydrates can be found as polymers, these polysaccharides can be of different types. Which ones
Name three heteropolysaccharides
What type of polysaccharide is glycogen
