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Immunology Quiz Personal

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Immunology Quiz Personal MedStudent

Question 1 of 121

1

A blood group has both A and B antigens but no antibodies, It is

Select one of the following:

  • B

  • AB

  • O

  • A

Explanation

Question 2 of 121

1

A compound formed in an organism for inhibiting growth of another organism is

Select one of the following:

  • Antigen

  • Antibody

  • Antibiotic

  • Antiallergic

Explanation

Question 3 of 121

1

A disease due to allergic reaction is

Select one of the following:

  • Enteric fever

  • Yellow fever

  • Hay fever

  • Trench fever

Explanation

Question 4 of 121

1

Which is involved in body defense?

Select one of the following:

  • Neutrophils

  • Macrophages

  • Lymphocytes

  • All the above

Explanation

Question 5 of 121

1

A doctor suggested to a couple not to have more than one child because of

Select one of the following:

  • Rh+ male Rh- female

  • Rh- male Rh+ female

  • Rh+ male Rh+ female

  • Rh- male Rh- female

Explanation

Question 6 of 121

1

A molecule that produces an immune response is

Select one of the following:

  • Antigen

  • Antibody

  • Carcinogen

  • Mutagen

Explanation

Question 7 of 121

1

A noninfectious unnatural and unusual reaction to a substance or condition is

Select one of the following:

  • Immunity

  • Allergy

  • Infection

  • Toxin

Explanation

Question 8 of 121

1

A person is injected with gammaglobulin against hepatitis B. It is

Select one of the following:

  • Artificially acquires passive immunity

  • Artificially acquires active immunity

  • Naturally acquires active immunity

  • Naturally acquires passive immunity

Explanation

Question 9 of 121

1

Acquired immunity as developed after vaccination or infection is found in

Select one of the following:

  • Vertebrates only

  • Invertebrates as well as vertebrates

  • Plants

  • All the above

Explanation

Question 10 of 121

1

Acquired immunity is found in

Select one of the following:

  • Invertebrates

  • Vertebrates

  • Some invertebrates

  • Both vertebrates and invertibrates

Explanation

Question 11 of 121

1

Active immunity is due to

Select one of the following:

  • Suppressor T-cells

  • killer T-cells

  • Memory cells

  • Helper T-cells

Explanation

Question 12 of 121

1

Active immunity means

Select one of the following:

  • Resistance developed before disease

  • Resistance developed after disease

  • Increased heart beat

  • Increased flow of blood

Explanation

Question 13 of 121

1

AIDS is caused by

Select one of the following:

  • RNA virus

  • DNA virus

  • Herpes virus

  • Hepatitis virus

Explanation

Question 14 of 121

1

An example of innate immunity is

Select one of the following:

  • T-lymphocytes

  • B-lymphocyte

  • Neutrophils

  • Thyroid cells

Explanation

Question 15 of 121

1

An insect bite may result in inflammation of that spot. It is triggered by alarm chemicals such as

Select one of the following:

  • Histamine and dopamine

  • Histamine and kinins

  • Interferon and opsonin

  • Interferons and histones

Explanation

Question 16 of 121

1

An Rh- individual receives Rh+ blood. The recipient becomes

Select one of the following:

  • Sterlite

  • Dead

  • No reaction

  • Isoimmunised

Explanation

Question 17 of 121

1

Which of the following are secondary lymphoid organs?

Select one or more of the following:

  • Spleen

  • Lymph Nodes

  • Thymus

  • Bone Marrow

  • Lymph Vessels

Explanation

Question 18 of 121

1

IgG consists of

Select one of the following:

  • 2 light chains and two heavy chains joined by di-sulphide bond (H2L2)

  • 2 light chains and two heavy chains joined by hydrogen bond (H2L2)

  • 2 light chains and a heavy chain joined by di-sulphide bond (H1L2)

  • a light chain and two heavy chains joined by di-sulphide bond (H2L1)

Explanation

Question 19 of 121

1

Which is the Ig that first reaches the site of infection?

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 20 of 121

1

Which is the largest Ig?

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 21 of 121

1

Which of the following statements are true regarding IgM?

Select one of the following:

  • IgM is a pentamer and is the largest Ig and called as ‘natural antibody’

  • IgM exists as monomer on B-cell surface

  • IgM is involved in early primary immune response

  • all of these

Explanation

Question 22 of 121

1

Which of the following statements are true?

Select one or more of the following:

  • IgM is involved in primary immune response

  • IgG is involved in primary immune response

  • Both IgM and IgG are involved in primary immune response

  • IgG is involved only in secondary immune response

Explanation

Question 23 of 121

1

The antibody present in secretions like tears, saliva, colostrum is

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 24 of 121

1

The primary Ig of exocrine secretions is

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 25 of 121

1

Antibodies are:

Select one of the following:

  • proteins

  • glycoproteins

  • carbohydrates

  • nucleic acid

Explanation

Question 26 of 121

1

The antigen binding site on an antibody is called:

Select one of the following:

  • endotope

  • paratope

  • epitope

  • antitope

Explanation

Question 27 of 121

1

An antibody has

Select one of the following:

  • 2 Fab regions and an Fc region

  • an Fab region and an Fc region

  • 2 Fab regions and 2 Fc regions

  • many Fab regions and many Fc regions

Explanation

Question 28 of 121

1

The hypervariable region resides in the

Select one of the following:

  • N terminal region of light chain

  • N-terminal region of light and heavy chain

  • C-terminal region of light chain

  • C-terminal region of light chain and heavy chain

Explanation

Question 29 of 121

1

Fab stands for

Select one of the following:

  • fragment antibody binding

  • fragment antigen binding

  • fragment antibody or antigen binding

  • fragment affinity binding

Explanation

Question 30 of 121

1

Which of the following statement is true regarding Fc region?

Select one of the following:

  • fragment crystalisation and is the constant region

  • fragment constant and is the variable region

  • fragment crystalisation and is the variable region

  • fragment crystalisation and has both variable and constant region

Explanation

Question 31 of 121

1

Fab region:

Select one of the following:

  • has a hypervariable region that binds with antibody

  • has a hypervariable region that binds with antigen

  • has a hypervariable region that binds with other immune cells

  • all of these

Explanation

Question 32 of 121

1

Fc region is involved in

Select one of the following:

  • cell surface receptor binding

  • complement activation

  • determining diffusivity of antibody molecule

  • all of these

Explanation

Question 33 of 121

1

The ability of antigen to stimulate antibody production is called

Select one of the following:

  • Affinity

  • Antigenicity

  • Elicitation

  • none of these

Explanation

Question 34 of 121

1

Clearance of antigens by antibodies involve

Select one of the following:

  • neutralization and agglutination

  • opsonisation and complement activation

  • precipitation

  • all of these

Explanation

Question 35 of 121

1

The two identical light chains of an antibody belongs to

Select one of the following:

  • kappa only

  • lambda only

  • lambda or kappa

  • none of these

Explanation

Question 36 of 121

1

Antigens can be

Select one of the following:

  • proteins

  • carbohydrates

  • nucleic acids

  • all of these

Explanation

Question 37 of 121

1

A molecule that reacts with specific antibody but is not immunogenic by itself is called

Select one of the following:

  • carrier

  • antigen

  • hapten

  • immunogen

Explanation

Question 38 of 121

1

Haptens are immunogenic upon binding covalently to a carrier protein how?

Select one of the following:

  • covalently to a carrier protein

  • covalently to an antibody

  • covalently to a paratope

  • none of these

Explanation

Question 39 of 121

1

Haptens cannot activate T cell or B cells due to:

Select one of the following:

  • its low molecular weight antigens arbuscules

  • its inability to bind to MHC

  • both a and b

  • none of these

Explanation

Question 40 of 121

1

Which of the following is a hapten?

Select one of the following:

  • Cyanide

  • Paracetamol

  • Penicillin

  • None of these

Explanation

Question 41 of 121

1

An incomplete antigens

Select one of the following:

  • are also called as haptens

  • are immunogenic upon binding covalently to a carrier protein

  • cannot induce antibody production by itself

  • all of the above

Explanation

Question 42 of 121

1

The second most abundant Ig is

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 43 of 121

1

The most effective Ig is:

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 44 of 121

1

IgM is a

Select one of the following:

  • pentamer with 10 antigen binding sites

  • tetramer with 8 antigen binding sites

  • monomer with 2 antigen binding sites

  • dimer with 4 antigen binding sites

Explanation

Question 45 of 121

1

The Ig that mediates allergic reaction is

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 46 of 121

1

The Ig involved in host defence against parasitic infection (helminths)

Select one of the following:

  • IgM

  • IgG

  • IgA

  • IgE

Explanation

Question 47 of 121

1

The bonds involved in antigen-antibody interactions are

Select one of the following:

  • weak hydrogen bonds and vanderwalls forces

  • strong covalent bonds

  • strong di- sulphide bonds

  • all of these

Explanation

Question 48 of 121

1

Which of the following statement is true?

Select one of the following:

  • all immunogens are antigens but all antigens are not immunogens

  • all immunogens are antigens and all antigens are immunogens

  • all immunogens are not antigens but all antigens are immunogens

  • all immunogens are proteins and all proteins are immunogens

Explanation

Question 49 of 121

1

Which of the statements are true regarding antigen?

Select one of the following:

  • generally self-molecules and molecules with low molecular weight are non-immunogenic

  • an antigen generally has many epitopes

  • heteropolymers are more immunogenic than homopolymers

  • all of these

Explanation

Question 50 of 121

1

The process of removal and replacement of damaged tissues or organs with healthy ones from a donor is called as

Select one of the following:

  • transplantation

  • replacement therapy

  • repair and replacement

  • none of these

Explanation

Question 51 of 121

1

The transfer of individuals own tissue to another part of the body is called

Select one of the following:

  • autograft

  • xenograft

  • allograft

  • syngeneic graft

Explanation

Question 52 of 121

1

The transfer of tissue between genetically identical individuals (like twins) is called

Select one of the following:

  • autograft

  • xenograft

  • allograft

  • syngeneic graft

Explanation

Question 53 of 121

1

The transfer of tissue between individuals of different species is called

Select one of the following:

  • autograft

  • xenograft

  • allograft

  • syngeneic graft

Explanation

Question 54 of 121

1

The transfer of tissue between genetically different individuals of same species is called

Select one of the following:

  • autograft

  • xenograft

  • allograft

  • syngeneic graft

Explanation

Question 55 of 121

1

Which of the following has the maximum transplantation success rate?

Select one of the following:

  • autograft

  • xenograft

  • allograft

  • syngeneic graft

Explanation

Question 56 of 121

1

The major molecules responsible for rejection of transplant is

Select one of the following:

  • B cells

  • T cells

  • MHC molecule

  • Antibodies

Explanation

Question 57 of 121

1

Which of the following statements are true regarding transplantation?

Select one of the following:

  • The compatibility of MHC proteins of donor and recipient will determine the success of transplantation

  • MHCs are just like fingerprints and all nucleated cells possess this fingerprint

  • The compatibility of MHC/HLA proteins of donor and recipient will be high if they are genetically closely related and may lead to successful transplantation.

  • all of these

Explanation

Question 58 of 121

1

In humans, MHC is called as

Select one of the following:

  • Human MHC

  • Homo MHC

  • Human leucocyte antigen (HLA)

  • All of the above

Explanation

Question 59 of 121

1

The genes for HLA proteins are clustered in the major histocompatibility complex located

Select one of the following:

  • on the short arm of chromosome 6

  • on the long arm of chromosome 6

  • on the short arm of chromosome 10

  • on the long arm of chromosome 10

Explanation

Question 60 of 121

1

The test that is done prior to transplantation surgery to determine the compatibility of MHC proteins between donor and recipient is called

Select one of the following:

  • MHC matching

  • MHC typing

  • tissue typing

  • blood HLA test

Explanation

Question 61 of 121

1

MHC class I is a cell surface molecule present on

Select one of the following:

  • B cells

  • All nucleated cells

  • APCs

  • T cells

Explanation

Question 62 of 121

1

MHC class II is a cell surface molecule present on
(most correct ans.)

Select one of the following:

  • B cells

  • All nucleated cells

  • APCs

  • T cells

Explanation

Question 63 of 121

1

Which of the following statements are true regarding complement activation?

Select one of the following:

  • lysis of pathogen, tumor cells and allografts

  • production of mediators that attracts neutrophils to the site of inflammation

  • opsonization

  • all of these

Explanation

Question 64 of 121

1

Complement system is involved in

Select one of the following:

  • specific defence

  • non-specific defence

  • both a and b

  • none of these

Explanation

Question 65 of 121

1

Allergy to penicillin is an example of

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 66 of 121

1

Type IV hypersensitivity is also called as:

Select one of the following:

  • immediate hypersensitivity

  • delayed hypersensitivity

  • cytotoxic hypersensitivity

  • immune complex hypersensitivity

Explanation

Question 67 of 121

1

The most common class of antibody involved in type II hypersensitivity is

Select one of the following:

  • IgG

  • IgM

  • IgE

  • IgD

Explanation

Question 68 of 121

1

T helper cell mediated hypersensitivity is:

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 69 of 121

1

Type III hypersensitivity is triggered by:

Select one of the following:

  • Mast cells and IgE

  • K cells and IgG

  • Deposition of antigen antibody complexes

  • Th cells

Explanation

Question 70 of 121

1

Autoimmune hemolytic anemia (AHA) is an example of

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 71 of 121

1

K cells and IgG mediated hypersensitivity is

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 72 of 121

1

Antibody dependent cytotoxicity is associated with

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 73 of 121

1

Allergies to sea foods, eggs etc is an example of

Select one of the following:

  • Type I hypersensitivity

  • Type II hypersensitivity

  • Type III hypersensitivity

  • Type IV hypersensitivity

Explanation

Question 74 of 121

1

Humoral immunity is mediated by

Select one of the following:

  • B cells

  • macrophages

  • both a and b

  • phagocytes

Explanation

Question 75 of 121

1

Humoral immunity is also called as

Select one of the following:

  • antibody mediated immunity

  • non-specific immune response

  • antigen mediated immunity

  • all of these

Explanation

Question 76 of 121

1

B cell has receptor on its surface which is

Select one of the following:

  • monomeric IgM

  • dimeric IgM

  • monomeric IgG

  • B cell receptor

Explanation

Question 77 of 121

1

B cells upon activation by antigens

Select one of the following:

  • undergo clonal expansion followed by clonal selection

  • divides continuously

  • undergo clonal selection followed by clonal expansion

  • secrete antibodies

Explanation

Question 78 of 121

1

B cells differentiates to form

Select one of the following:

  • plasma cells only

  • effector cells only

  • plasma cells and memory B cells

  • none of these

Explanation

Question 79 of 121

1

Which of the following statement is incorrect regarding plasma cells?

Select one of the following:

  • Plasma cells are the effector cells

  • Plasma cells secretes antibodies

  • The precursor of plasma cell is B cell

  • Plasma cell has surface receptors

Explanation

Question 80 of 121

1

Origin and maturation of B cells takes place at

Select one of the following:

  • lymph nodes

  • bone marrow

  • thymus

  • spleen

Explanation

Question 81 of 121

1

The function of memory B cell is

Select one of the following:

  • antibody production

  • immunologic memory

  • regulated antibody production

  • none of these

Explanation

Question 82 of 121

1

Generally antibodies produced against a pathogen is

Select one of the following:

  • monoclonal

  • homogenous

  • polyclonal

  • all of same specificity

Explanation

Question 83 of 121

1

Antibodies produced by plasma cells are

Select one of the following:

  • specific

  • produced against the epitope that triggered B cell activation

  • both a and b

  • diverse

Explanation

Question 84 of 121

1

Antibodies clear out antigens by

Select one of the following:

  • neutralization

  • precipitation

  • agglutination

  • all of these

Explanation

Question 85 of 121

1

Antibodies are

Select one of the following:

  • opsonins

  • lipoproteins

  • serum phagocytes

  • none of these

Explanation

Question 86 of 121

1

Any substance that promotes phagocytosis of antigens by binding to them are called as

Select one of the following:

  • interleukins

  • macrophages

  • phagocytes

  • opsonins

Explanation

Question 87 of 121

1

The phenomenon of selective proliferation of B cells in response to their interaction with the antigen is called

Select one of the following:

  • clonal expansion

  • monoclonal selection

  • clonal proliferation

  • clonal selection

Explanation

Question 88 of 121

1

The specific targeted responses constitute the third line of defense in response to an infectious agent and is called as

Select one of the following:

  • third line of defence

  • adaptive immunity

  • acquired immunity

  • all of these

Explanation

Question 89 of 121

1

The characteristics of adaptive immunity include

Select one of the following:

  • specificity

  • immunologic memory

  • discrimination of self from non self molecules

  • all of these

Explanation

Question 90 of 121

1

Which of the cells are involved in adaptive immunity?

Select one of the following:

  • B cells and T cells

  • B cells only

  • T cells only

  • macrophages and NK cells

Explanation

Question 91 of 121

1

T cell mediates

Select one of the following:

  • humoral immunity

  • non-specific defence

  • cell mediated immunity

  • none of these

Explanation

Question 92 of 121

1

The ratio of T cells to B cells is

Select one of the following:

  • 3:1

  • 1:3

  • 1:1

  • 1:2

Explanation

Question 93 of 121

1

T cells and B cells are originated in

Select one of the following:

  • spleen

  • thymus

  • bone marrow

  • lymph nodes

Explanation

Question 94 of 121

1

Injection of anti-venom against snake bite is an example of

Select one of the following:

  • active immunity

  • passive immunity

  • non-specific immunity

  • phagocytic immunity

Explanation

Question 95 of 121

1

Which of the following statements are true regarding adaptive immunity?

Select one of the following:

  • prior exposure to antigen is essential

  • prior exposure to antigen is not essential

  • it is a non-specific defence mechanism

  • macrophages are the major cells involved

Explanation

Question 96 of 121

1

Active immunity involves

Select one of the following:

  • contact with foreign antigens

  • immunologic memory

  • slow primary response

  • all of the above

Explanation

Question 97 of 121

1

Active immunity is produced by

Select one of the following:

  • clonal selection

  • clonal expansion

  • both a and b

  • all of these

Explanation

Question 98 of 121

1

Cells involved in adaptive immunity or acquired immunity or specific defense include

Select one of the following:

  • T cells

  • B cells

  • Antigen presenting cells

  • All of these

Explanation

Question 99 of 121

1

Plasma cells are secreted by

Select one of the following:

  • T cells

  • B cells

  • Antigen presenting cells

  • Macrophages

Explanation

Question 100 of 121

1

The characteristics of passive immunity include

Select one of the following:

  • immediate relief

  • no immunologic memory

  • resistance for a short period only

  • all of these

Explanation

Question 101 of 121

1

Immunologic memory is provided by

Select one of the following:

  • B cells

  • T cells

  • Both a and b

  • Phagocytes

Explanation

Question 102 of 121

1

A method for cell sorting based on the surface antigens (markers) which react specifically with fluorescent-labelled antibodies is called

Select one of the following:

  • Flowcytometry

  • Immunofluorescent technique

  • Immunoelectrophoresis

Explanation

Question 103 of 121

1

A technique in which tissues and cells are examined by a fluorescent light microscope using fluorescent-labeled antibodies is called

Select one of the following:

  • Immunofluorescent technique

  • Flowcytometry

  • Immunoelectrophoresis

Explanation

Question 104 of 121

1

A technique for the identification of proteins in serum or other fluid by electrophoresis and subsequent immunodiffusion is called

Select one of the following:

  • Immunoelectrophoresis

  • Flowcytometry

  • Immunofluorescent technique

Explanation

Question 105 of 121

1

Classical pathway of complement system is activated by

Select one of the following:

  • antibody-antigen complexes

  • antigen

  • antigenic peptides

  • antigens bound to MH

Explanation

Question 106 of 121

1

Alternate pathway of complement system is activated by

Select one of the following:

  • antibody-antigen complexes

  • antigen

  • microorganisms or its toxins

  • antigens bound to MHC

Explanation

Question 107 of 121

1

Classical pathway of complement system is involved in

Select one of the following:

  • specific defence

  • adaptive immunity

  • both a and b

  • non-specific defence

Explanation

Question 108 of 121

1

Alternate pathway of complement system is involved in

Select one of the following:

  • non-specific defence

  • innate immunity

  • both a and b

  • adaptive immunity

Explanation

Question 109 of 121

1

Complement system

Select one of the following:

  • consists of 20 serum proteins

  • serum proteins acts as biological cascade

  • both a and b

  • are set of antibodies

Explanation

Question 110 of 121

1

Complement system is involved in

Select one of the following:

  • specific defence

  • non-specific defence

  • both a and b

  • none of these

Explanation

Question 111 of 121

1

Kupffer cells are macrophages found on

Select one of the following:

  • lung

  • bone

  • nephrons

  • liver

Explanation

Question 112 of 121

1

Antiviral glycoproteins released by living cells in response to viral attack and induce a viral resistant state to neighboring cells is called as

Select one of the following:

  • natural killer cells

  • complement system

  • phagocytes

  • interferons

Explanation

Question 113 of 121

1

Newborns get their antibodies from mothers milk. This is an example of

Select one of the following:

  • Naturally acquired active immunity

  • Artificially acquired active immunity

  • Naturally acquired passive immunity

  • Artificially acquired passive immunity

Explanation

Question 114 of 121

1

Which of the following is the site of T cell maturation?

Select one of the following:

  • Bone marrow

  • Thymus

  • Spleen

  • Appendix

Explanation

Question 115 of 121

1

Primary lymphoid organs include

Select one of the following:

  • Thymus and spleen

  • Thymus and bone marrow

  • Thymus, bone marrow and spleen

  • Thymus, bone marrow, spleen and lymph nodes

Explanation

Question 116 of 121

1

The major chemical messenger involved in hypersensitivity is

Select one of the following:

  • interferons

  • histamines

  • lymphokines

  • interleukines

Explanation

Question 117 of 121

1

HIV attacks:

Select one of the following:

  • macrophages

  • B cells

  • T cytotoxic cells

  • T helper cells

Explanation

Question 118 of 121

1

Regarding the inflammatory response:

Select one of the following:

  • Tissue swelling is the first stage of the inflammatory response.

  • Mast cells secrete chemotactic agents that attract lymphocytes

  • Macrophages secrete vasoactive materials during the inflammatory response

  • The inflammatory response can be triggered by antibody binding to the surface of micro-organisms.

Explanation

Question 119 of 121

1

Natural killer cells only destroy cells infected with a virus.

Select one of the following:

  • True
  • False

Explanation

Question 120 of 121

1

Select from the dropdown lists to complete the text.

The antigens below are on your erythrocytes (red blood cells) which antibodies would you expect to find in the serum
1/ A- ( B, A, AB, O )
2/ B- ( A, B, AB, O )
3/ O- ( AB, O, A, B )

Explanation

Question 121 of 121

1

Fill the blank spaces to complete the text.

Fill in the Blanks (No - symbol needed)
1/ Precursor Chain + = H-Antigen
2/ H-Antigen + = A-Antigen
3/ H-Antigen + = B-Antigen

Explanation

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