52 y/o male s/p kidney transplant 5 years ago is admitted from the ED for hypoxia, SOB and decreased mental status requiring intubation for airway protection. You get limited information about the patient’s history, only knowing that the patient has had delayed rejection of his kidney and has been receiving high dose steroids for treatment. Per the patient’s family, he has had fever with progressive dry cough for several days. He has been getting progressively worse and went to the ED due to his SOB and concerns for new onset confusion.
In the ED, a chest X-ray was performed showing normal appearing lungs. On admission to the ED, his vitals are: Temp: 38.3, RR: 32, HR: 119, BP: 113/74, MAP: 87, Sat: 72% on RA, ht is 6’1”, Wt: 87kg and his ABG drawn before intubation is: 7.5/20/52/20/70% sat on RA.
The patient is intubated with succinylcholine, etomidate, morphine and versed. The ventilator has been set at: Pressure Assist Control ventilation with Pinsp: 25, f: 18, PEEP:5, FiO2: 100%. After 30 minutes his ABG shows 7.45/28/80/20/94% on 100% FiO2 with a respiratory rate of 23. The patient is started on empiric antibiotics with cefepime and vancomycin, treatment dose bactrim and steroids for potential PJP infection.
Over the course of the next 24 hrs, the patient’s chest X-ray evolves to show bilateral ground glass opacities. Over the next 12 hours, his saturations dip to the low 80s while PEEP is up titrated to 14 on 100% FiO2. The patient’s ABG at this time shows: pH: 7.29/49/53/24/ 83%.
On Pressure Assist Control Ventilation, what do you expect to see happen?
Select one of the following: