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Year 2 (Insulin & Glucagon) Quiz on Insulin Receptors, created by gina_evans0312 on 06/03/2014.

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Insulin Receptors

Question 1 of 13

1

Where is the carboxylase termunus regulatory region found?

Select one of the following:

  • Inside the cell

  • Outside the cell

  • In the membrane

Explanation

Question 2 of 13

1

How are the alpha and beta chains connected?

Select one of the following:

  • Electrostatic interactions

  • Disulphide bonds

Explanation

Question 3 of 13

1

What is the active site of insulin receptor?

Select one of the following:

  • Tyrosine kinase

  • Skeletons

  • Toast

Explanation

Question 4 of 13

1

The active site of Insulin receptors work exactly the same as other tyrosine kinases

Select one of the following:

  • True
  • False

Explanation

Question 5 of 13

1

What does IRS stand for?

Select one of the following:

  • Inland Revenue Service

  • Insulin Receptor Substrate

Explanation

Question 6 of 13

1

There are six different versions of the IRS

Select one of the following:

  • True
  • False

Explanation

Question 7 of 13

1

How does the IRS bind to the Insulin receptor?

Select one of the following:

  • PTB- Phosphotyrosine Binding Site

  • PSB- Phosphoserine Binding Sire

Explanation

Question 8 of 13

1

The Insulin Receptor response pathway is the same as the MAPK pathway until MAPK activates

Select one of the following:

  • Insulin Sensitive Protein Kinase (ISPK)

  • Insulin Responsive Protein Kinase (IRPK)

  • Insulin Dependent Protein Kinase (IDPK)

Explanation

Question 9 of 13

1

ISPK activates Protein Phosphatase 1, which reverses te effect of adrenaline/glucagon through phoshphorylation

Select one of the following:

  • True
  • False

Explanation

Question 10 of 13

1

IRS can also work through the PI3K pathway, leading to the conversion of PI2 to what?

Select one of the following:

  • PI

  • PI3

  • PI-2,5-BP

Explanation

Question 11 of 13

1

The action of the PI3K pathway causes the activation of PKB

Select one of the following:

  • True
  • False

Explanation

Question 12 of 13

1

The P of PKB causes the P and deactivation of what?

Select one of the following:

  • Glycogen Synthase Kinase-3

  • Glycogen Phosphorylase

Explanation

Question 13 of 13

1

Why does PKB increase phosphodiesterase activity?

Select one of the following:

  • Reverses phosphorylation done by glucaon

  • Lowers cAMP

Explanation

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