Sophie Barrett
Quiz by , created more than 1 year ago

Aetiology Pathophysiology Clinical Features Biochemical Tests

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Sophie Barrett
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Jaundice

Question 1 of 11

1

Jaundice is characterised by a yellow discolouration of the skin and sclera.

Select one of the following:

  • True
  • False

Explanation

Question 2 of 11

1

Which of the following best describes the cause of the colour change seen in jaundice patients.

Select one of the following:

  • Too little bilirubin in the skin.

  • Hyperbiliruinaemia

  • Bilirubin getting trapped in the skin and not metabolised.

Explanation

Question 3 of 11

1

Bilirubin is derived from tetrapyrole prosthetic group found in lymphocytes.

Select one of the following:

  • True
  • False

Explanation

Question 4 of 11

1

Which of the following are the 3 main causes of why bilirubin levels may rise in blood?

Select one or more of the following:

  • Haemolysis of red blood cells.

  • Bilirubin in prescription medications.

  • Failure of the conjugating mechanism.

  • Obstruction in the biliary system.

Explanation

Question 5 of 11

1

Increased bilirubin production as a result of haemolysis gives...

Select one of the following:

  • ...a predominantly unconjugated hyperbilirubinaemia.

  • ...a predominantly unconjugated hypobilirubinaemia.

  • ...a predominantly conjugated hyperbilirubinaemia.

  • ...a predominantly conjugated hypobilirubinaemia.

Explanation

Question 6 of 11

1

Phototherapy should be offered to babies with jaundice if their bilirubin level approaches:

Select one of the following:

  • >200 microlitres per litre.

  • >40 microlitres per litre.

  • >300 microlitres per litre.

  • >100 millilitres per litre.

Explanation

Question 7 of 11

1

Which of the following best describes the effect of a complete blockage of the bile duct by a gallstone?

Select one of the following:

  • Bilirubin and alkaline phosphatae are raised. Little or no urobilinogen in the urine and the stools will be pale.

  • Bilirubin is raised and hence, the stools are dark.

  • Bilirubin urobilinogen are raised, with pale stools and urine.

Explanation

Question 8 of 11

1

Bilirubin is partly digested by gut bacteria to produce stercobilinogen - this is partly reabsorbed and re-excreted in the urine as urobilinogen.

Select one of the following:

  • True
  • False

Explanation

Question 9 of 11

1

Unconjugated bilirubin is normally bound to albumin, but is water-soluble.

Select one of the following:

  • True
  • False

Explanation

Question 10 of 11

1

Which 2 of the following are the most common causes of jaundice in adults?

Select one or more of the following:

  • Paracetamol Poisoning

  • Viral Hepatitis

  • Excessive Alcohol Consumption.

  • Secondary Neoplasm in the Liver

Explanation

Question 11 of 11

1

A more unusual cause of jaundice is seen in neonates that have...

Select one of the following:

  • been born more than 3 weeks premature.

  • an alpha 1 - antitrypsin defiency (Wilson's Disease).

  • been born to a mother who drunk excessive amounts of alcool throughout pregnancy.

Explanation