Anti-Diabetic Drugs Quiz

Question 1 of 85

1

Which of the following drugs are the only medications approved for the use in the treatment of Type 1 DM?

Select one or more of the following:

Pramlintide (Symlin)
Miglitol (Gylset)
Insulin
Pioglitazone (Actos)

Explanation

Question 2 of 85

1

Increntin hormones like GLP-1 and GIP stimulate insulin secretion in response to meals

Select one of the following:

True
False

Explanation

Question 3 of 85

1

Click on each orange point and select the correct answer.

Specify how each of the following specified areas contribute to the pathophysiology of Type 2 DM

{"10.6545_31.1072":[{"id":12605085,"answer":"decreased glucose uptake","x":10.6545,"y":31.1072},{"id":12605086,"answer":"decreased incretin effect","x":10.6545,"y":31.1072},{"id":12605087,"answer":"increased lipolysis","x":10.6545,"y":31.1072},{"id":12605088,"answer":"decreased insulin secretion (beta cells)","x":10.6545,"y":31.1072}],"34.1517_33.3922":[{"id":12605089,"answer":"decreased glucose uptake","x":34.1517,"y":33.3922},{"id":12605090,"answer":"increased production of glucose","x":34.1517,"y":33.3922},{"id":12605091,"answer":"neurotransmitter dysfunction","x":34.1517,"y":33.3922},{"id":12605092,"answer":"increased glucagon secretion","x":34.1517,"y":33.3922}],"62.1574_30.1521":[{"id":12605093,"answer":"increased lipolysis","x":62.1574,"y":30.1521},{"id":12605094,"answer":"decreased glucose uptake","x":62.1574,"y":30.1521},{"id":12605095,"answer":"increase production of glucose","x":62.1574,"y":30.1521},{"id":12605096,"answer":"increase glucose reabsorption","x":62.1574,"y":30.1521}],"11.3831_86.1486":[{"id":12605170,"answer":"decreased insulin secretion (beta cells)","x":11.3831,"y":86.1486},{"id":12605171,"answer":"increased glucagon secretion (alpha cell","x":11.3831,"y":86.1486},{"id":12605172,"answer":"decreased incretin effect","x":11.3831,"y":86.1486},{"id":12605173,"answer":"increased lipolysis","x":11.3831,"y":86.1486}],"82.7856_32.1926":[{"id":12605109,"answer":"neurotransmitter dysfunction","x":82.7856,"y":32.1926},{"id":12605110,"answer":"increased glucose reabsorption","x":82.7856,"y":32.1926},{"id":12605111,"answer":"decreased incretin effect","x":82.7856,"y":32.1926},{"id":12605112,"answer":"increase glucagon secretion","x":82.7856,"y":32.1926}],"45.8093_91.5756":[{"id":12605154,"answer":"decreased glucose uptake","x":45.8093,"y":91.5756},{"id":12605155,"answer":"increased production of glucose","x":45.8093,"y":91.5756},{"id":12605156,"answer":"decreased incretin effect","x":45.8093,"y":91.5756},{"id":12605157,"answer":"increased glucagon secretion (alpha)","x":45.8093,"y":91.5756}],"66.7565_94.9175":[{"id":12605144,"answer":"increased glucagon secretion (alpha cell","x":66.7565,"y":94.9175},{"id":12605145,"answer":"decreased glucose uptake","x":66.7565,"y":94.9175},{"id":12605146,"answer":"increased glucose reabsorption","x":66.7565,"y":94.9175},{"id":12605147,"answer":"increased lipolysis","x":66.7565,"y":94.9175}],"88.4323_89.0049":[{"id":12605119,"answer":"neurotransmitter dysfunction","x":88.4323,"y":89.0049},{"id":12605120,"answer":"increased lipolysis","x":88.4323,"y":89.0049},{"id":12605121,"answer":"decrease glucose uptake","x":88.4323,"y":89.0049},{"id":12605122,"answer":"increased production of glucose","x":88.4323,"y":89.0049}]}

Explanation

Question 4 of 85

1

Pramlintide (Symlin) belongs to what drug class?

Select one of the following:

alpha-glucosidase inhibitors
amylinomimetics
Megltinides
Sulfonylureas

Explanation

Question 5 of 85

1

What type of efficacy does the following anti-diabetic drugs have?

Metformin, Sulfonyureas, TZDs, GLP-1

Select one of the following:

Low efficacy (< 0.5 decrease in A1C)
Intermediate efficacy (~0.5-1 % decrease in A1C)
High efficacy ( ~1-2% decrease in A1C)

Explanation

Question 6 of 85

1

What type of efficacy do the following drugs have?

SGLT2, DPP-IV, Alpha-glucosidase inhibitors

Select one of the following:

High efficacy (~1-2% decrease in A1C)
Intermediate efficacy (~0.5-1% decrease in A1C)
Low efficacy (< 0.5% decrease in A1C)

Explanation

Question 7 of 85

1

Of the following anti-diabetic drugs, which have the lowest efficacy in regards to the lowering of the A1C?

Select one or more of the following:

Colesvelam
Metformin
Insulins
Bromocriptine

Explanation

Question 8 of 85

1

Fill the blank space to complete the text.

has a BBW for severe HYPOglycemia

Explanation

Question 9 of 85

1

Which of the following are contraindications for Pramlintide (Symlin)?

Select one or more of the following:

gastroparesis
HYPOglycemic unawareness
poor compliance with drug insulin regimens
pediatric patients
inflammatory bowel disease
colonic ulceration

Explanation

Question 10 of 85

1

Fill the blank space to complete the text.

If taking anti-diabetic drug , the meal time insulin must reduced by 50%.

Explanation

Question 11 of 85

1

Pramlintide (Symlin) must be injected immediately prior to each major meal.

Select one of the following:

True
False

Explanation

Question 12 of 85

1

Miglitol (Glyset) and Acarbose (Precose) belong to what anti-diabetic drug class?

Select one of the following:

Amylinomimetics
alpha-glucosidase inhibitors
Biguanides
TZD's

Explanation

Question 13 of 85

1

What is the MOA for the alpha-glucosidase inhibitors?

Select one of the following:

activation of amylin
activates the nuclear transcription factor PPAR-gamma
inhibits intestinal alpha glucosidase
activates GLP-1 receptors

Explanation

Question 14 of 85

1

Select from the dropdown list to complete the text.

The ( alpha-glucosidase, secretagogues, TZDs, Biguanides ) drug class slows intestinal carbohydrate digestion/absorption.

Explanation

Question 15 of 85

1

Alpha-glucosidase drugs must be taken with the 1st bite of each meal

Select one of the following:

True
False

Explanation

Question 16 of 85

1

Which of the following are adverse drug reactions for alpha-glucosidase class?

Select one or more of the following:

GI disturbances
flatulence
headache
elevation in hepatic enzymes

Explanation

Question 17 of 85

1

Select from the dropdown list to complete the text.

Contrainidcations for the ( alpha-glucosidase inhibitors, amylinomimetics, DPP-IV, Meglitinides ) include inflammatory bowel disease, colonic ulceration, intestinal obstruction, malabsorption, and CrCL < 25 mL/min

Explanation

Question 18 of 85

1

Hypoglycemia must be treated with what when taking an alpha glucosidase inhibitor.

Select one of the following:

complex carbs
insulins
simple carbohydrates

Explanation

Question 19 of 85

1

Which of the following are the mechanisms of action for the biguanides class?

Select one or more of the following:

decrease glucose production from the liver
closes a K(ATP) channels on beta-cell plasma membranes
increases insulin sensitivity in muscle
decrease carbohydrate uptake in gut

Explanation

Question 20 of 85

1

Which of the following are the mechanisms of action for the biguanides class?

Select one or more of the following:

closes K(ATP) channels on beta-cell plasma membranes
decreases glucose production form liver
increases insulin sensitivity in muscle
decreases uptake in gut

Explanation

Question 21 of 85

1

What is the physiological action of the Biguanides class?

Select one of the following:

increases insulin secretions
decreases hepatic glucose production
increases incretin levels
decreases glucagon secretion

Explanation

Question 22 of 85

1

Select from the dropdown list to complete the text.

The maximum effective does for Metformin (Glucophage) is ( 2000, 1500, 1000, 2250 ) mg/day

Explanation

Question 23 of 85

1

Metformin (Glucophage) has a BBW for lactic acidosis

Select one of the following:

True
False

Explanation

Question 24 of 85

1

Fill the blank space to complete the text.

Iodinated contrast media, unstable HF, eGFR < 30 mL/min, hepatic dysfunction, dehydration, pre-renal azotemia, hypoxic states, CKD, and acidosis are all contraindications for

Explanation

Question 25 of 85

1

Fill the blank space to complete the text.

is the first line therapy for T2DM.

Explanation

Question 26 of 85

1

Starting metformin in patients with an eGFR between 45-50 mL/min/1.73m is not recommended.

Select one of the following:

True
False

Explanation

Question 27 of 85

1

The following drugs belong to what class?

Glyburide (Micronase)
Glyburide (Micronized) - (Glynase)
Glipizide (Glucotrol)
Glimepiride (Amaryl)

Select one of the following:

Biguanides
DDP-IV
TZD's
Sulfonylureas

Explanation

Question 28 of 85

1

Closure of the K(ATP) channels on beta-cell plasma membranes is the MOA for what class(es) of drugs?

Select one or more of the following:

Sulfonylureas
TZDs
Bile Acid sequestrants
Meglitinides

Explanation

Question 29 of 85

1

Which of the following are ADR's for the sulfonylurea class?

Select one or more of the following:

HYPOglycemia
SIADH
photosensitivity
GI disturbances
B12 deficiency
induced ovulation in PCOS
sulfa-allergy

Explanation

Question 30 of 85

1

Fill the blank space to complete the text.

should NOT be used in elderly patients or patients with hepatic impairment

Explanation

Question 31 of 85

1

Which of the sulfonylureas can be used during pregnancy?

Select one of the following:

Glyburide (Micronase)
Glipizide (Glucotrol)
Glimepiride (Amaryl)

Explanation

Question 32 of 85

1

For the sulfonylurea class, 1/2 of the max dose is equal to 80% drug effectiveness

Select one of the following:

True
False

Explanation

Question 33 of 85

1

Sulfonylureas can be used in combination with insulin

Select one of the following:

True
False

Explanation

Question 34 of 85

1

Glynase can be interchanged with the drug Mirconase.

Select one of the following:

True
False

Explanation

Question 35 of 85

1

Fill the blank space to complete the text.

Of the sulfonylureas, should be utilized in patients with renal impariement.

Explanation

Question 36 of 85

1

Which of the following drugs are Meglitinides?

Select one or more of the following:

Nateglinide (Starlix)
Pioglitazone (Actos)
Repaglinide (Prandin)
Rosiglitazone (Avandia)

Explanation

Question 37 of 85

1

Which of the following are ADR's for the Meglitinides?

Select one or more of the following:

increased fluid retention
bladder cancer
HYPOglycemia
dizziness
GI disturbances

Explanation

Question 38 of 85

1

Fill the blank space to complete the text.

can be antidiabetic drug that can be reccommended for patients who are meal skippers.

Explanation

Question 39 of 85

1

Repaglinide (Prandin) is contraindicated with Gemfibrozil

Select one of the following:

True
False

Explanation

Question 40 of 85

1

Which drugs listed below belong the Thiazolidinediones (TZDs) class?

Select one or more of the following:

Sitagliptin (Januvia)
Linagliptin (Tradjenta)
Pioglitazone (Actos)
Rosiglitazone (Avandia)

Explanation

Question 41 of 85

1

What is the MOA for the Thiazolidinediones class?

Select one of the following:

closure of the K(ATP) channels on the beta-cell membranes
activates dopaminergic receptors
activates GLP-1 receptors
activates the nuclear transcription factor PPAR-gamma

Explanation

Question 42 of 85

1

What is the physiological action for the TZD class?

Select one of the following:

increases insulin secretion
increases insulin sensitivity in the skeletal muscle, adipocytes, and liver
decreases hepatic glucose production

Explanation

Question 43 of 85

1

Select from the dropdown list to complete the text.

( TZDs, Meglitinides, DPP-IV inhibitors, Bile Acid Sequestrants ) have a BBW warning for heart failure

Explanation

Question 44 of 85

1

Select the ADRs of the TZD class

Select one or more of the following:

increase in fluid retention
dizziness
peripheral edema
hepatotoxicity
bladder cancer
fractures
macular edema

Explanation

Question 45 of 85

1

Which patient should not take TZDs for their diabetes?

Select one or more of the following:

Patients with Class III or IV heart failure
Patient with Type 1 DM
Patients with the risk of bone fracture

Explanation

Question 46 of 85

1

Of the TZD drugs, which has an improved lipid profile?

Select one of the following:

Pioglitazone (Actos)
Rosiglitazone (Avandia)

Explanation

Question 47 of 85

1

TZDs can be used in combination with Metformin

Select one of the following:

True
False

Explanation

Question 48 of 85

1

Fill the blank space to complete the text.

is a bile acid sequestrant

Explanation

Question 49 of 85

1

Binds bile acids in intestinal tract, increasing hepatic bile acid production and activates the farnesoid X receptor (FXR) in the liver is the MOA for what drug class?

Select one of the following:

Dopamine agonist
Bile acid sequestrant
DPP-IV inhibitors
Biguanides

Explanation

Question 50 of 85

1

Indicate the physiological actions of the bile acid sequestrant class?

Select one or more of the following:

Decreases hepatic glucose production
increases incretin levels
increases insulin sensitivity
activates GLP-1 receptors

Explanation

Question 51 of 85

1

Which of the following are ADR's for bile acid sequestrant?

Select one or more of the following:

constipation
increases in TG
pancreatitis
decreases absorption of other medications
GI upset
fatigue

Explanation

Question 52 of 85

1

Bowel obstructions, TG > 500 mg/dL, and history of hypertriglyceridemia-induced pancreatitis are contraindications for ....

Select one of the following:

Dopamine agonist
Bile acid sequestrant
DPP-IV
SGLT-2

Explanation

Question 53 of 85

1

Colesevelam (Welchol) can be approved for monotherapy

Select one of the following:

True
False

Explanation

Question 54 of 85

1

Bromocriptine (Cycloset) belongs to what anti-diabetic drug class?

Select one of the following:

Bile acid sequestrant
SGLT-2
Dopamine agonist
GLP-1

Explanation

Question 55 of 85

1

What is the MOA for Bromocriptine (Cycloset)?

Select one of the following:

inhibits DPP-IV activity
activates GLP-1 receptors
inhibits SGLT-2 in the proximal tubule
activates dopaminergic receptors

Explanation

Question 56 of 85

1

What are the physiological actions for the Dopamine agonist class?

Select one or more of the following:

modulates HYPOthalamic regulation of metabolism
decrease hepatic glucose production
increased incretin levels
increased insulin sensitivity

Explanation

Question 57 of 85

1

Postural hypotension, headache, fatigue, hallucinations, psychotic disorder, pleural effusion, pulmonary fibrosis, and GI ulcers are the ADR's for what drug?

Select one of the following:

Colesevelam (Welchol)
Bromocriptine (Cycloset)
Sitagliptin (Januvia)
Liraglutide (Victoza)

Explanation

Question 58 of 85

1

Which of the following are contraindications for the Bromocriptine (Cycloset)?

Select one or more of the following:

Hypersensitivity to ergot derivation or dopamine
lactation
syncopal migraines
severe renal impairment

Explanation

Question 59 of 85

1

Bromocriptine (Cycloset) is not approved for monotherapy.

Select one of the following:

True
False

Explanation

Question 60 of 85

1

What drug class do the following drugs belong to?

Sitagliptin (Januvia)
Saxagliptin (Onglyza)
Linagliptin (Tradjenta)
Alogliptin (Nesina)

Select one of the following:

DPP-IV
SGLT2 inhibitors
Dopamine agonist
GLP-1 agonist

Explanation

Question 61 of 85

1

Inhibits DPP-IV activity, increasing postprandial active incretin concentrations is the MOA for what drug class?

Select one of the following:

GLP-1
TZDs
Biguanides
DPP-IV inhibitors

Explanation

Question 62 of 85

1

What are the physiological actions for the DPP-IV inhibitors? (select all that apply)

Select one or more of the following:

increases insulin secretion (glucose-dependent)
increase renal excretion of glucose
decrease glucagon secretion (glucose-dependent)
slows gastric emptying

Explanation

Question 63 of 85

1

Of the DPP-IV inhibitors, which one does not need to be adjusted in renal and hepatic impairment?

Select one of the following:

Alogliptin (Nesina)
Linagliptin (Tradjenta)
Saxagliptin (Onglyza)
Sitagliptin (Januvia)

Explanation

Question 64 of 85

1

ADR's for DPP-IV's include which of the following

Select one or more of the following:

upper respiratory infection
peripheral edema
decreased BP
pancreatitis
SJS
rhabdomyolysis

Explanation

Question 65 of 85

1

Select from the dropdown list to complete the text.

FDA warns that ( DPP-4 inhibitors, SGLT-2, GLP-1 inhibitors, TZDs ) may cause severe joint pain that can be severe or diabiling

Explanation

Question 66 of 85

1

Which of the DPP-IV inhibitors can cause heart failure?

Select one or more of the following:

Sitagliptin (Januvia)
Saxagliptin (Onglyza)
Linagliptin (Tradjenta)
Alogliptin (Nesina)

Explanation

Question 67 of 85

1

The following drugs belong to what drug class?

Exenatide (Byetta)
Liraglutide (Victoza)
Abiglutide (Tanzeum)
Dulagultide (Trulicity)

Select one of the following:

GLP-1 agonist
TZDs
DPP-IV
SGLT-2

Explanation

Question 68 of 85

1

Select the physiological actions of the GLP-1 class

Select one or more of the following:

increases insulin secretion (glucose-dependent)
decreases glucagon (glucose-dependent)
slows gastric emptying
increases satiety

Explanation

Question 69 of 85

1

Of the GLP-1 agonist, which one can not be used if the CrCL is < 30 mL/min?

Select one of the following:

Exenatide (Byetta)
Liraglutide (Victoza)
Abiglutide (Tanzeum)
Dulaglutide (Trulicity)

Explanation

Question 70 of 85

1

Of the GLP-1 inhibitors, which ones have a BBW warning for thyroid carcinoma?

Select one or more of the following:

Exenatide (Byetta)
Liraglutide (Victoza)
Abiglutide (Tanzeum)
Dulaglutide (Trulicity)

Explanation

Question 71 of 85

1

Select from the dropdown list to complete the text.

History of pancreatitis, gastroparesis or GI disease, and caution in renal impairment are all contrainidcations for the ( GLP-1 agonist, DPP-IV, TZDs, SGLT-2 )

Explanation

Question 72 of 85

1

The following drugs belong to what drug class?

Canagliflozin (Invokana)
Dapagliflozin (Farxiga)
Empagliflozin (Jardiance)

Select one of the following:

SGLT-2 inhibitors
DPP-IV
Biguanides
Meglitinides

Explanation

Question 73 of 85

1

Which of the following are ADR's for the SGLT-2 inhibitor drug class?

Select one or more of the following:

female & male genital mycotic infections
increased urination
increased BP
decreased BP
pancreatitis
hypovolemia
hyperkalemia

Explanation

Question 74 of 85

1

Hypovolemia must be corrected prior to starting a SGLT-2 inhibitor

Select one of the following:

True
False

Explanation

Question 75 of 85

1

Select from the dropdown list to complete the text.

Increased risk of bladder cancer and bone fracture with ( Dapagliflozin (Farxiga), Canagliflozin (Invokana), Empagliflozin (Jardiance) )

Explanation

Question 76 of 85

1

Select from the dropdown list to complete the text.

( Empagliflozin (Jardiance), Canagliflozin (Invokana), Dapagliflozin (Farxiga) ) is assocaited with an increase in CV events

Explanation

Question 77 of 85

1

Select from the dropdown list to complete the text.

( Canagliflozin (Invokana), Dapagliflozin (Farxiga), Empagliflozin (Jardiance) ) may be associated with an increase in lower extremity amputations

Explanation

Question 78 of 85

1

Which drug classes target fasting BG only!

Select one or more of the following:

Biguanides
TZDs
SGLT-2
Amylinomimetics

Explanation

Question 79 of 85

1

Which drug classes targets post-prandial blood glucose only!

Select one or more of the following:

Biguanides
Sulfonylureas
Amylinomimetics
alpha-glucosidase inhibitors
dopamine agonist
DPP-4 inhibitors
meglitinides

Explanation

Question 80 of 85

1

What drug classes target BOTH fasting and postprandial BG levels?

Select one or more of the following:

Sulfonylureas
TZDs
SGLT-2 inhibitors
Bile acid sequestrants

Explanation

Question 81 of 85

1

Select from the dropdown list to complete the text.

GLP-1 agonist, Metformin, SGLT-2, Amylinmimetics all cause ( weight loss, weight gain, weight neutral )

Explanation

Question 82 of 85

1

Select from the dropdown list to complete the text.

Metformin, alpha-glucosidase inhibitors, DPP-IV inhibitors all cause ( weight gain, weight loss, weight neutral )

Explanation

Question 83 of 85

1

Select from the dropdown list to complete the text.

Suflonylureas, Meglitinides, insulins, and TZDs all cause ( weight loss, weight gain, weight neutral )

Explanation

Question 84 of 85

1

Which drug classes are high cost agents?

Select one or more of the following:

GLP-1
SGLT-2
DPP-IV
Insulins
Metformin
Sulfonylureas
TZDs

Explanation

Question 85 of 85

1

Which drugs classes are low cost agents?

Select one or more of the following:

Metformin
Sulfonylureas
DPP-IV
TZDs
GLP-1
SGLT-2

	Created by Mark W. almost 8 years ago

NAPLEX Pharmacy (Endo) Quiz on Anti-Diabetic Drugs Quiz , created by Mark W. on 12/12/2016.

Anti-Diabetic Drugs Quiz

Question 1 of 85

Which of the following drugs are the only medications approved for the use in the treatment of Type 1 DM?

Select one or more of the following:

Explanation

Question 2 of 85

Increntin hormones like GLP-1 and GIP stimulate insulin secretion in response to meals

Select one of the following:

Explanation

Question 3 of 85

Click on each orange point and select the correct answer.

Specify how each of the following specified areas contribute to the pathophysiology of Type 2 DM

Explanation

Question 4 of 85

Pramlintide (Symlin) belongs to what drug class?

Select one of the following:

Explanation

Question 5 of 85

What type of efficacy does the following anti-diabetic drugs have? Metformin, Sulfonyureas, TZDs, GLP-1

Select one of the following:

Explanation

Question 6 of 85

What type of efficacy do the following drugs have? SGLT2, DPP-IV, Alpha-glucosidase inhibitors

Select one of the following:

Explanation

Question 7 of 85

Of the following anti-diabetic drugs, which have the lowest efficacy in regards to the lowering of the A1C?

Select one or more of the following:

Explanation

Question 8 of 85

Fill the blank space to complete the text.

has a BBW for severe HYPOglycemia

Explanation

Question 9 of 85

Which of the following are contraindications for Pramlintide (Symlin)?

Select one or more of the following:

Explanation

Question 10 of 85

Fill the blank space to complete the text.

If taking anti-diabetic drug , the meal time insulin must reduced by 50%.

Explanation

Question 11 of 85

Pramlintide (Symlin) must be injected immediately prior to each major meal.

Select one of the following:

Explanation

Question 12 of 85

Miglitol (Glyset) and Acarbose (Precose) belong to what anti-diabetic drug class?

Select one of the following:

Explanation

Question 13 of 85

What is the MOA for the alpha-glucosidase inhibitors?

Select one of the following:

Explanation

Question 14 of 85

Select from the dropdown list to complete the text.

The alpha-glucosidase secretagogues TZDs Biguanides( alpha-glucosidase, secretagogues, TZDs, Biguanides ) drug class slows intestinal carbohydrate digestion/absorption.

Explanation

Question 15 of 85

Alpha-glucosidase drugs must be taken with the 1st bite of each meal

Select one of the following:

Explanation

Question 16 of 85

Which of the following are adverse drug reactions for alpha-glucosidase class?

Select one or more of the following:

Explanation

Question 17 of 85

Select from the dropdown list to complete the text.

Contrainidcations for the alpha-glucosidase inhibitors amylinomimetics DPP-IV Meglitinides( alpha-glucosidase inhibitors, amylinomimetics, DPP-IV, Meglitinides ) include inflammatory bowel disease, colonic ulceration, intestinal obstruction, malabsorption, and CrCL < 25 mL/min

Explanation

Question 18 of 85

Hypoglycemia must be treated with what when taking an alpha glucosidase inhibitor.

Select one of the following:

Explanation

Question 19 of 85

Which of the following are the mechanisms of action for the biguanides class?

Select one or more of the following:

Explanation

Question 20 of 85

Which of the following are the mechanisms of action for the biguanides class?

What type of efficacy does the following anti-diabetic drugs have?

Metformin, Sulfonyureas, TZDs, GLP-1

What type of efficacy do the following drugs have?

SGLT2, DPP-IV, Alpha-glucosidase inhibitors

The ( alpha-glucosidase, secretagogues, TZDs, Biguanides ) drug class slows intestinal carbohydrate digestion/absorption.

Contrainidcations for the ( alpha-glucosidase inhibitors, amylinomimetics, DPP-IV, Meglitinides ) include inflammatory bowel disease, colonic ulceration, intestinal obstruction, malabsorption, and CrCL < 25 mL/min

The maximum effective does for Metformin (Glucophage) is ( 2000, 1500, 1000, 2250 ) mg/day

The following drugs belong to what class?

Glyburide (Micronase)
Glyburide (Micronized) - (Glynase)
Glipizide (Glucotrol)
Glimepiride (Amaryl)