Pregnancy and Lactation

Question 1 of 58

1

How many weeks constitute a term pregnancy?

Select one of the following:

24-30 weeks
30-35 weeks
37-42 weeks
44-46 weeks

Explanation

Question 2 of 58

1

Click on each orange point and select the correct answer.

Fill the table below with the appropriate Physiologic/Pharmacokinetic changes

{"33.241_17.9211":[{"id":12658975,"answer":"increase in hepatic metabolism","x":33.241,"y":17.9211},{"id":12658976,"answer":"decrease in hepatic metabolism","x":33.241,"y":17.9211}],"33.5321_39.0739":[{"id":12658977,"answer":"thinning of barrier","x":33.5321,"y":39.0739},{"id":12658978,"answer":"thickening of barrier","x":33.5321,"y":39.0739}],"60.4624_17.8285":[{"id":12658991,"answer":"increase metabolism","x":60.4624,"y":17.8285},{"id":12658992,"answer":"decreased metabolism","x":60.4624,"y":17.8285}],"33.1555_58.7321":[{"id":12658979,"answer":"increased renal blood flow","x":33.1555,"y":58.7321},{"id":12658980,"answer":"decreased renal blood flow","x":33.1555,"y":58.7321}],"61.2157_36.2656":[{"id":12658993,"answer":"increased distribution","x":61.2157,"y":36.2656},{"id":12658994,"answer":"decreased distribution","x":61.2157,"y":36.2656}],"24.675_75.2728":[{"id":12658981,"answer":"increased blood volume","x":24.675,"y":75.2728},{"id":12658982,"answer":"decreased blood volume","x":24.675,"y":75.2728}],"55.7517_57.1438":[{"id":12658995,"answer":"increased GFR","x":55.7517,"y":57.1438},{"id":12658996,"answer":"decreased GFR","x":55.7517,"y":57.1438}],"80.2365_32.9689":[{"id":12659007,"answer":"increased maternal concentration","x":80.2365,"y":32.9689},{"id":12659008,"answer":"decreased maternal concentration","x":80.2365,"y":32.9689}],"42.76_76.1008":[{"id":12658983,"answer":"increased albumin concentration","x":42.76,"y":76.1008},{"id":12658984,"answer":"decreased albumin concentration","x":42.76,"y":76.1008}],"86.6395_18.6527":[{"id":12659005,"answer":"increased concentration","x":86.6395,"y":18.6527},{"id":12659006,"answer":"decreased concentration","x":86.6395,"y":18.6527}],"68.7487_58.2437":[{"id":12658997,"answer":"increased elimination","x":68.7487,"y":58.2437},{"id":12658998,"answer":"decreased elimination","x":68.7487,"y":58.2437}],"54.6244_76.4061":[{"id":12658999,"answer":"increased distribution","x":54.6244,"y":76.4061},{"id":12659000,"answer":"decreased distribution","x":54.6244,"y":76.4061}],"24.1159_90.936":[{"id":12658985,"answer":"decrease motility","x":24.1159,"y":90.936},{"id":12658986,"answer":"increased motility","x":24.1159,"y":90.936}],"32.9632_90.9312":[{"id":12658987,"answer":"increased intestinal blood flow","x":32.9632,"y":90.9312},{"id":12658988,"answer":"decreased intestinal blood flow","x":32.9632,"y":90.9312}],"43.1366_92.5843":[{"id":12658989,"answer":"increased gastric pH","x":43.1366,"y":92.5843},{"id":12658990,"answer":"decreased gastric pH","x":43.1366,"y":92.5843}],"68.5604_76.4061":[{"id":12659001,"answer":"increased protein binding","x":68.5604,"y":76.4061},{"id":12659002,"answer":"decreased protein binding","x":68.5604,"y":76.4061}],"92.8541_43.958":[{"id":12659009,"answer":"increased fetal concentration","x":92.8541,"y":43.958},{"id":12659010,"answer":"decreased fetal concentration","x":92.8541,"y":43.958}],"86.2628_56.87":[{"id":12659011,"answer":"increased concentration","x":86.2628,"y":56.87},{"id":12659012,"answer":"decreased concentration","x":86.2628,"y":56.87}],"55.9427_92.0654":[{"id":12659003,"answer":"increased absorption","x":55.9427,"y":92.0654},{"id":12659004,"answer":"decreased absorption","x":55.9427,"y":92.0654}],"80.6098_75.8499":[{"id":12659013,"answer":"increase concentration","x":80.6098,"y":75.8499},{"id":12659014,"answer":"decrease concentration","x":80.6098,"y":75.8499}],"95.679_76.1313":[{"id":12659015,"answer":"increased free drug concentration","x":95.679,"y":76.1313},{"id":12659016,"answer":"decreased free drug concentration","x":95.679,"y":76.1313}],"86.8278_93.1643":[{"id":12659017,"answer":"increased concentration","x":86.8278,"y":93.1643},{"id":12659018,"answer":"decreased concentration","x":86.8278,"y":93.1643}]}

Explanation

Question 3 of 58

1

Which of the following are true in regards to medication use in pregnancy? (select all that apply)

Select one or more of the following:

eliminate nonessential drugs
discourage self-medication
minimize exposure to harmful medications
adjust doses for use during pregnancy

Explanation

Question 4 of 58

1

What vaccinations should be administered during pregnancy?

Select one or more of the following:

Inactivated influenza vaccine
Tdap ( @ 27-36 weeks)
Hepatitis B
Hepatitis A
Meningitis

Explanation

Question 5 of 58

1

Why are multivitamins used during pregnancy?

Select one of the following:

fetal bone development
maternal and fetal erythropoiesis
prevent neural tube defect

Explanation

Question 6 of 58

1

Why is calcium used during pregnancy?

Select one or more of the following:

maternal and fetal erythropoiesis
fetal bone development
prevent neural tube defect
prevention of HTN

Explanation

Question 7 of 58

1

Fill the blank space to complete the text.

is used during pregnancy to prevent neural tube defects

Explanation

Question 8 of 58

1

Fill the blank space to complete the text.

Drugs with a molecular weight of less than daltons readily cross the placenta barrier.

Explanation

Question 9 of 58

1

Lipophilic drugs will cross the placental barrier more than hydrophilic drugs

Select one of the following:

True
False

Explanation

Question 10 of 58

1

Which albumin levels are higher, fetal or maternal?

Select one of the following:

fetal
maternal

Explanation

Question 11 of 58

1

Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier

Select one of the following:

True
False

Explanation

Question 12 of 58

1

Fill the blank space to complete the text.

Only drugs can cross placental membranes

Explanation

Question 13 of 58

1

Fill the blank space to complete the text.

Blood flow to impacts drug transfer to fetus

Explanation

Question 14 of 58

1

What is the drug of choice for the treatment of hyperemesis gravidarum?

Select one of the following:

ondansetron
pyridoxine
doxylamine
phosphoric acid

Explanation

Question 15 of 58

1

Select from the dropdown list to complete the text.

The treatment of choice for nausea and vomiting during pregnancy is ( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

Explanation

Question 16 of 58

1

What is the first line or drug of choice for nausea and vomiting during pregnancy?

Select one or more of the following:

pyridoxine
doxylamine
phosphoric acid
metoclopramide

Explanation

Question 17 of 58

1

Select from the dropdown list to complete the text.

For nausea and vomiting during pregnancy, ( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Explanation

Question 18 of 58

1

Select from the dropdown lists to complete the text.

Nausea and Vomiting
2nd line therapy is ( metoclopramide, ondansetron, doxylamine, promethazine )
3rd line therapy is ( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

Explanation

Question 19 of 58

1

Fill the blank spaces to complete the text.

First line line treatment for constipation during pregnancy is incerase and intake

Explanation

Question 20 of 58

1

What drugs should not be used to treat constipation during pregnancy?

Select one or more of the following:

osmotic laxatives
docusate
castor oil
mineral oil
senna
bsicodyl

Explanation

Question 21 of 58

1

Select from the dropdown lists to complete the text.

GERD/Heartburn

1st line: ( Lifestyle Modifications, antacids or sucralfate, metoclopramide, PPIs )
2nd line: ( antacids or sucralfate, sodium bicarbonate, Ranitidine, PPIs )

Explanation

Question 22 of 58

1

Which of the following treatment can be used to treat Hemorrhoids during a pregnancy?

Select one or more of the following:

Higher fiber intake
increase oral fluid intake
use sitz baths
Topical anesthetics, protectants, and astringents
tylenol

Explanation

Question 23 of 58

1

Bulk forming agents should be utilized to treat diarrhea during pregnancy, what drugs should be avoided?

Select one or more of the following:

Diphenoxylate/atropine
paregoric
bismuth subsalicylate
psyllium/fiber

Explanation

Question 24 of 58

1

Saline nasal spray/drops are safe to use during pregnancy in the treatment of cough, colds, and allergies

Select one of the following:

True
False

Explanation

Question 25 of 58

1

What is the drug of choice to treat cold , cough, and allergies during pregnancy?

Select one of the following:

chlorpheniramine
diphenhydramine
loratidine
budesonide

Explanation

Question 26 of 58

1

What drugs are recommended during the 2nd and 3rd trimesters in the treatment of cough, cold, and allergies during pregnancy?

Select one or more of the following:

diphenhydramine
loratidine
cetirizine
beclomethasone

Explanation

Question 27 of 58

1

What nasal steroids are recommended for chronic allergies during pregnancy?

Select one or more of the following:

Budesonide (Rhinocort)
Beclomethasone (Beconase AQ)
Advair

Explanation

Question 28 of 58

1

Select from the dropdown list to complete the text.

( Acetaminophen, opioids, NSAIDs, aspirin ) is the drug of choice for acute pain managment during pregnancy

Explanation

Question 29 of 58

1

What is the drug of choice in the treatment of HTN and severe eclampsia?

Select one of the following:

labetalol
hydralazine
IV magnesium

Explanation

Question 30 of 58

1

Fill the blank space to complete the text.

IV is used for seizure protection and treatment

Explanation

Question 31 of 58

1

Fill the blank spaces to complete the text.

Pharmacological treatment for gestational HTN should be started if the systolic BP is greater than OR the diastolic is greater than

Explanation

Question 32 of 58

1

Fill the blank spaces to complete the text.

Essential/Gestational HTN

1st line (DOC):
2nd line:

Explanation

Question 33 of 58

1

Coagulation Disorders

You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies

Select one of the following:

True
False

Explanation

Question 34 of 58

1

Fill the blank spaces to complete the text.

Coagulation Disorders

1st line:
2nd line:

Treatment is to be contiuned through pregnancy and weeks after delivery (including breastfeeding)

Explanation

Question 35 of 58

1

Which of the following drugs are contraindicated in the treatment of UTIs during pregnancy?

Select one or more of the following:

Cephalexin
Ampicillin
SMX-TMP
Fluoroquinolines
Tetracyclines

Explanation

Question 36 of 58

1

What are the top drug choices in the treatment of UTIs during pregnancy?

Select one or more of the following:

Cephalexin
Ampicillin
Nitrofurantoin
Tetracyclines

Explanation

Question 37 of 58

1

What drugs are utilized in the treatment of pyelonephritis?

Select one or more of the following:

Ceftriaxone
Ampicillin plus gentamicin
Ampicillin-sulbactam
nitrofurantoin
cephalexin

Explanation

Question 38 of 58

1

Select from the dropdown lists to complete the text.

STI's

Drug of choice syphillis: ( penicillin G, ceftriaxone, amoxicillin, erythromycin )
Drug of choice for gonorrhea: ( ceftriaxone, penicillin G, amoxicillin, erythromycin )
Durg of choice for chlamydia: ( amoxicillin, ceftriaxone, penicillin G, erythromycin ) ; 2nd line: ( erythromycin, amoxicillin, ceftriaxone, penicillin G )

Explanation

Question 39 of 58

1

Acyclovir/valacyclovir is used in the treatment of genital herpes during pregnancy

Select one of the following:

True
False

Explanation

Question 40 of 58

1

Fill the blank space to complete the text.

is the treatment of choice for bacterial vaginosis, and the alternative treatment is clindaymcin

Explanation

Question 41 of 58

1

Fill the blank spaces to complete the text.

Asthma

is the short acting beta agonist of choice and is the inhaled corticosteriod of choice during preganancy

Explanation

Question 42 of 58

1

During pregnancy, changing agents to minimize risk is NOT recommended for the treatment of epilepsy

Select one of the following:

True
False

Explanation

Question 43 of 58

1

What drugs are the safest to use to treat epilepsy during pregnancy?

Select one or more of the following:

lamotrigine
levetiracetam
valproic acid
carbamazepine

Explanation

Question 44 of 58

1

Select from the dropdown lists to complete the text.

HIV during pregnancy

New diagnosed: ( HAART, Zidovudine, efavirenz, clindamycin )
( Zidovudine, HAART, efavirenz, clindamycin ) is the mainstay of antiretroviral therapy
Avoid ( efavirenz, Zidovudine, HAART, clindamycin )

Explanation

Question 45 of 58

1

Treatment of schizophrenia, bipolar disorder, depression usually needs to be continued during pregnancy and breastfeeding; high relapse rates if discontinued

Select one of the following:

True
False

Explanation

Question 46 of 58

1

What are the most preferred agents in the treatment of mental health issues in pregnant women?

Select one or more of the following:

fluoxetine
citalopram
escitalopram
levetiracetam

Explanation

Question 47 of 58

1

Nortriptyline and desipramine are TCAs of choice in the treatment of mental health issues during pregnancy

Select one of the following:

True
False

Explanation

Question 48 of 58

1

Fill the blank spaces to complete the text.

Treatment of choice for HYPOthryoridism:
Treatment of choice for HYPERthryroidism: or

Explanation

Question 49 of 58

1

Fill the blank space to complete the text.

is the prcoess of stopping contractions

Explanation

Question 50 of 58

1

What drugs are utilized in pre-term labor and tocolysis?

Select one or more of the following:

IV magnesium
terbutaline
nifedipine
promethazine

Explanation

Question 51 of 58

1

What drugs are needed for cervical ripening?

Cervical ripening: in order to dilate, collagen must loosen and separate; moisture necessary; occurs naturally in women who spontaneously enter labor

Select one or more of the following:

misoprostol
dinoprostone
oxytocin
methylergonovine

Explanation

Question 52 of 58

1

Select from the dropdown lists to complete the text.

Labor induction

1st line: ( oxytocin, Methylergonovine, misoprostol, dinoprostone )
2nd line: ( methylergonovine, dinoprostone, misoprostol, Oxytocin )

Explanation

Question 53 of 58

1

Fill the blank space to complete the text.

If mother colonized with Group B Streptococcus:

Explanation

Question 54 of 58

1

Analgesia can prolong the 1st and 2nd stages of labor

Select one of the following:

True
False

Explanation

Question 55 of 58

1

Fill the blank space to complete the text.

analgesia has better profile than parenteral opioids (poor maternal pain relief and less vigorous neonates)

Explanation

Question 56 of 58

1

Fill the blank spaces to complete the text.

Drug FactorsGeneral Guidelines

Most drugs appear in breast milk to some degree. Most common mechanism of transfer is passive diffusion.

Levels of most drugs in breast milk do not usually exceed 1% to 2% of ingested maternal dosage

If the milk/plasma ratio of drug and active metabolites is less than , it is usually safe to breastfeed

RID: If infant dose is less than % of maternal dose (weight adjusted), it is usually safe to breastfeed

Explanation

Question 57 of 58

1

Depression

Sertraline and paroxetine are most frequently prescribed with few reported adverse effects,

Select one of the following:

True
False

Explanation

Question 58 of 58

1

breast milk is more acidic; weak bases are more likely to stay trapped in breast milk “ion trapping:

Select one of the following:

True
False

	Created by Mark W. almost 8 years ago

NAPLEX Pharmacy (Endo) Quiz on Pregnancy and Lactation, created by Mark W. on 14/12/2016.

Pregnancy and Lactation

Question 1 of 58

How many weeks constitute a term pregnancy?

Select one of the following:

Explanation

Question 2 of 58

Click on each orange point and select the correct answer.

Fill the table below with the appropriate Physiologic/Pharmacokinetic changes

Explanation

Question 3 of 58

Which of the following are true in regards to medication use in pregnancy? (select all that apply)

Select one or more of the following:

Explanation

Question 4 of 58

What vaccinations should be administered during pregnancy?

Select one or more of the following:

Explanation

Question 5 of 58

Why are multivitamins used during pregnancy?

Select one of the following:

Explanation

Question 6 of 58

Why is calcium used during pregnancy?

Select one or more of the following:

Explanation

Question 7 of 58

Fill the blank space to complete the text.

is used during pregnancy to prevent neural tube defects

Explanation

Question 8 of 58

Fill the blank space to complete the text.

Drugs with a molecular weight of less than daltons readily cross the placenta barrier.

Explanation

Question 9 of 58

Lipophilic drugs will cross the placental barrier more than hydrophilic drugs

Select one of the following:

Explanation

Question 10 of 58

Which albumin levels are higher, fetal or maternal?

Select one of the following:

Explanation

Question 11 of 58

Fetal blood pH < maternal, therefore weak bases more easily cross, ionize, and less likely to diffuse back across the placental barrier

Select one of the following:

Explanation

Question 12 of 58

Fill the blank space to complete the text.

Only drugs can cross placental membranes

Explanation

Question 13 of 58

Fill the blank space to complete the text.

Blood flow to impacts drug transfer to fetus

Explanation

Question 14 of 58

What is the drug of choice for the treatment of hyperemesis gravidarum?

Select one of the following:

Explanation

Question 15 of 58

Select from the dropdown list to complete the text.

The treatment of choice for nausea and vomiting during pregnancy is nonpharmacological treatment pyridoximine and doxylamine emetrol( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

Explanation

Question 16 of 58

What is the first line or drug of choice for nausea and vomiting during pregnancy?

Select one or more of the following:

Explanation

Question 17 of 58

Select from the dropdown list to complete the text.

For nausea and vomiting during pregnancy, phosphoric acid metoclopramide dopamine diclegis( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Explanation

Question 18 of 58

Select from the dropdown lists to complete the text.

Nausea and Vomiting 2nd line therapy is metoclopramide ondansetron doxylamine promethazine( metoclopramide, ondansetron, doxylamine, promethazine ) 3rd line therapy is dopamine antagonist dicelgis ondansetron methylprednisone( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

Explanation

Question 19 of 58

Fill the blank spaces to complete the text.

First line line treatment for constipation during pregnancy is incerase and intake

Explanation

Question 20 of 58

What drugs should not be used to treat constipation during pregnancy?

The treatment of choice for nausea and vomiting during pregnancy is ( nonpharmacological treatment, pyridoximine and doxylamine, emetrol )

For nausea and vomiting during pregnancy, ( phosphoric acid, metoclopramide, dopamine, diclegis ) should not be used if the patient is a diabetic

Nausea and Vomiting
2nd line therapy is ( metoclopramide, ondansetron, doxylamine, promethazine )
3rd line therapy is ( dopamine antagonist, dicelgis, ondansetron, methylprednisone )

GERD/Heartburn

1st line: ( Lifestyle Modifications, antacids or sucralfate, metoclopramide, PPIs )
2nd line: ( antacids or sucralfate, sodium bicarbonate, Ranitidine, PPIs )

( Acetaminophen, opioids, NSAIDs, aspirin ) is the drug of choice for acute pain managment during pregnancy

Essential/Gestational HTN

1st line (DOC):
2nd line:

Coagulation Disorders

You need to continue treatment for women with history of Deep Vein Thrombosis/Pulmonary Embolism, Mitral Valve Replacement, clotting factor deficiencies, antiphospholipid antibodies

Coagulation Disorders

1st line:
2nd line:

Treatment is to be contiuned through pregnancy and weeks after delivery (including breastfeeding)