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BSc (Hons) Biology Quiz on Cancer & Autoimmune Disease: Quiz the Second, created by Sami-Jaine on 09/05/2013.

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Cancer & Autoimmune Disease: Quiz the Second

Question 1 of 10

1

In carcinogenesis...
Initiation _____ Progression

Select one of the following:

  • Promotion

  • Prominent

  • Prometric

Explanation

Question 2 of 10

1

Altered DNA bases (mutations) are the basis of cellular changes that cause cancer. True or False?

Select one of the following:

  • True

  • False

Explanation

Question 3 of 10

1

"New Growth" - abnormal and continued growth of cells which are no longer subject to homeostatic controls typical or normal tissue... this definition best describes...

Select one of the following:

  • Oncogene

  • Neoplasm

  • Leukaemia

Explanation

Question 4 of 10

1

Which 3 of the following influences Tumour Growth Rate?

Select one or more of the following:

  • The rate new cells replace old cells

  • Space

  • Blood Supply

  • Hormone levels (hormone-dependent tumours)

Explanation

Question 5 of 10

1

"A type of specific unresponsiveness to an antigen. It is induced but the exposure of specific lymphocytes to that antigen"

What does this best describe?

Select one of the following:

  • Autoimmunity

  • Cancer

  • Tolerance

Explanation

Question 6 of 10

1

Peripheral tolerance occurs in...

Select one or more of the following:

  • lymph nodes

  • lymph follicles in tonsils, payer's patches, spleen, adenoids, skin

  • arms, legs, hands and feet

Explanation

Question 7 of 10

1

Self Tolerance describes....

Select one of the following:

  • A normal individual who is tolerant of their own antigens

  • An autoimmune individuals who is tolerant of their own antigens

  • A normal individual who is tolerant of foreign antigens

Explanation

Question 8 of 10

1

Two signals are required for full T cell activation. What are the sources of these signals?

Select one or more of the following:

  • The Antigen

  • The MHC

  • The APC

  • The YMCA

Explanation

Question 9 of 10

1

Which of the following are features of Central Tolerance?

Select one or more of the following:

  • Apoptotic cell death

  • In the thyroid and bone marrow

  • Deleting those immature cells that have a strong affinity for self antigens

  • Negative Selection

  • In the thymus and bone marrow

  • No apoptosis occurs

Explanation

Question 10 of 10

1

"The immune system constantly looks for abnormal cells, eliminating cancer cells that arise. Some cancer cells may evade this immune system process and develop into tumours."

What does this describe?

Select one of the following:

  • Immune Surveillance Theory

  • Carcinogenesis

  • Mutagenic effect

Explanation

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