Created by Victoria Wright
over 7 years ago
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Which bacteria with exotoxins inhibit protein synthesis?
Inhibit protein synthesis
What toxin is associated with Corynebacterium diphtheriae?
Inhibit protein synthesis
What toxin is associated with Pseudomonas aeruginosa?
Inhibit protein synthesis
What toxin is associated with Shigella spp.?
Inhibit protein synthesis
What toxin is associated with Enterohemorrhagic E coli (EHEC)?
Increase fluid secretion
What toxin is associated with Enterotoxigenic E coli (ETEC)?
Increase fluid secretion
What toxin is associated with Bacillus anthracis?
Increase fluid secretion
What toxin is associated with Vibrio cholerae?
Inhibit phagocytic ability
What toxin is associated with Bordetella pertussis?
Inhibit release of neurotransmitter
What toxin is associated with Clostridium tetani?
Inhibit release of neurotransmitter
What toxin is associated with Clostridium botulinum?
Lyse cell membranes
What toxin is associated with Clostridium
perfringens?
Lyse cell membranes
What toxin is associated with Streptococcus pyogenes?
Superantigens causing shock
What toxin is associated with Staphylococcus aureus?
Superantigens causing shock
What toxin is associated with Streptococcus pyogenes?
Which bacteria with exotoxins Increase fluid secretion?
Which bacteria with exotoxins inhibit phagocytic ability?
Which bacteria with exotoxins inhibit release of neurotransmitter?
Which bacteria with exotoxins Lyse cell membranes?
Which bacteria with exotoxins are superantigens causing shock?
What bacteria with exotoxins are associated with the following toxin?
Exotoxin A
What bacteria with exotoxins are associated with the following toxin?
Toxic shock syndrome toxin
(TSST-1)
What bacteria with exotoxins are associated with the following toxin?
Streptolysin O
What bacteria with exotoxins are associated with the following toxin?
Alpha toxin
What bacteria with exotoxins are associated with the following toxin?
Botulinum toxin
What bacteria with exotoxins are associated with the following toxin?
Tetanospasmin
What bacteria with exotoxins are associated with the following toxin?
Pertussis toxin
What bacteria with exotoxins are associated with the following toxin?
Cholera toxin
What bacteria with exotoxins are associated with the following toxin?
Edema toxin
What bacteria with exotoxins are associated with the following toxin?
Heat-labile toxin (LT)
What bacteria with exotoxins are associated with the following toxin?
Heat-stable toxin (ST)
What bacteria with exotoxins are associated with the following toxin?
Shiga-like toxin (SLT)
What bacteria with exotoxins are associated with the following toxin?
Shiga toxin (ST)
What bacteria with exotoxins are associated with the following toxin?
Diphtheria toxin
What is the mechanism for the following bacteria with exotoxins?
Corynebacterium diphtheriae
(Diphtheria toxin)
What is the mechanism for the following bacteria with exotoxins?
Pseudomonas aeruginosa
(Exotoxin A)
What is the mechanism for the following bacteria with exotoxins?
Shigella spp.
(Shiga toxin (ST))
What is the mechanism for the following bacteria with exotoxins?
Enterohemorrhagic E coli (EHEC)
(Shiga-like toxin (SLT))
What is the mechanism for the following bacteria with exotoxins?
Enterotoxigenic E coli (ETEC)
(Heat-labile toxin (LT))
What is the mechanism for the following bacteria with exotoxins?
Enterotoxigenic E coli (ETEC)
(Heat-stable toxin (ST))
What is the mechanism for the following bacteria with exotoxins?
Bacillus anthracis
(Edema toxin)
What is the mechanism for the following bacteria with exotoxins?
Vibrio cholerae
(Cholera toxin)
What is the mechanism for the following bacteria with exotoxins?
Bordetella pertussis
(Pertussis toxin)
What is the mechanism for the following bacteria with exotoxins?
Clostridium tetani
(Tetanospasmin)
What is the mechanism for the following bacteria with exotoxins?
Clostridium botulinum
(Botulinum toxin)
What is the mechanism for the following bacteria with exotoxins?
Clostridium perfringens
(Alpha toxin)
What is the mechanism for the following bacteria with exotoxins?
Streptococcus pyogenes
(Streptolysin O)
What is the mechanism for the following bacteria with exotoxins?
Streptococcus pyogenes
(Exotoxin A)
What is the mechanism for the following bacteria with exotoxins?
Staphylococcus aureus
(Toxic shock syndrome toxin (TSST-1))
What is the manifestation of the following bacteria with exotoxins?
Staphylococcus aureus
(Toxic shock syndrome toxin (TSST-1))
What is the manifestation of the following bacteria with exotoxins?
Streptococcus pyogenes
(Exotoxin A)
What is the manifestation of the following bacteria with exotoxins?
Streptococcus pyogenes
(Streptolysin O)
What is the manifestation of the following bacteria with exotoxins?
Clostridium perfringens
(Alpha toxin)
What is the manifestation of the following bacteria with exotoxins?
Clostridium botulinum
(Botulinum toxin)
What is the manifestation of the following bacteria with exotoxins?
Clostridium tetani
(Tetanospasmin)
The following is the manifestation of what bacteria with exotoxins?
Spastic paralysis, risus sardonicus, and “lockjaw”; toxin prevents release of inhibitory (GABA and glycine) neurotransmitters from Renshaw cells in spinal cord.
The following is the manifestation of what bacteria with exotoxins?
Flaccid paralysis, floppy baby; toxin prevents release of stimulatory (ACh) signals at neuromuscular junctions leads to flaccid paralysis
What is the manifestation of the following bacteria with exotoxins?
Bordetella pertussis
(Pertussis toxin)
The following is the manifestation of what bacteria with exotoxins?
Whooping cough—child coughs on expiration and “whoops” on inspiration (toxin may not actually be a cause of cough; can cause “100-day cough” in adults)
What is the manifestation of the following bacteria with exotoxins?
Vibrio cholerae
(Cholera toxin)
The following is the manifestation of what bacteria with exotoxins?
Voluminous “rice-water” diarrhea
What is the manifestation of the following bacteria with exotoxins?
Bacillus anthracis
(Edema toxin)
The following is the manifestation of what bacteria with exotoxins?
Likely responsible for characteristic edematous borders of black eschar in cutaneous anthrax
What is the manifestation of the following bacteria with exotoxins?
Enterotoxigenic E coli (ETEC)
(Heat-liable toxin (LT) and Heat-stable toxin (ST)
The following is the manifestation of what bacteria with exotoxins?
Watery diarrhea: “labile in the Air (Adenylate cyclase), stable on the Ground (Guanylate cyclase)”
What is the manifestation of the following bacteria with exotoxins?
Enterohemorrhagic E coli (EHEC)
(Shiga-like toxin (SLT))
The following is the manifestation of what bacteria with exotoxins?
SLT enhances cytokine release, causing HUS (prototypically in EHEC serotype O157:H7). Unlike Shigella, EHEC does not invade host cells
What is the manifestation of the following bacteria with exotoxins?
Shigella spp
(Shiga toxin (ST))
The following is the manifestation of what bacteria with exotoxins?
GI mucosal damage leads to dysentery; ST also enhances cytokine release, causing hemolyticuremic syndrome (HUS)
What is the manifestation of the following bacteria with exotoxins?
Pseudomonas aeruginosa
(Exotoxin A)
The following is the manifestation of what bacteria with exotoxins?
Host cell death
What is the manifestation of the following bacteria with exotoxins?
Corynebacterium diphtheriae
(Diphtheria toxin)
The following is the manifestation of what bacteria with exotoxins?
Pharyngitis with pseudomembranes in throat and severe lymphadenopathy (bull neck)
The following is the manifestation of what bacteria with exotoxins?
Degradation of phospholipids leads to myonecrosis (“gas gangrene”) and hemolysis (“double zone” of hemolysis on blood agar)
The following is the manifestation of what bacteria with exotoxins?
Lyses RBCs; contributes to β-hemolysis;
host antibodies against toxin (ASO) used to diagnose rheumatic fever (do not confuse with immune complexes of poststreptococcal glomerulonephritis
The following is the manifestation of what bacteria with exotoxins?
Toxic shock syndrome: fever, rash, shock; other toxins cause scalded skin syndrome (exfoliative toxin) and food poisoning (heat-stable enterotoxin)
The following is the manifestation of what bacteria with exotoxins?
Toxic shock–like syndrome: fever, rash, shock; scarlet fever