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BSc Biomedical Science Year 1 Quiz on Cytoskeleton, Extracellular Matrix and Cell Junctions Quiz, created by rachel-chads on 28/05/2014.

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Cytoskeleton, Extracellular Matrix and Cell Junctions Quiz

Question 1 of 22

1

What is the monomer of microtubules?

Select one of the following:

  • Tubulin

  • Actin

  • Collagen

Explanation

Question 2 of 22

1

Tubulin is a homodimer.

Select one of the following:

  • True
  • False

Explanation

Question 3 of 22

1

The addition of tubulin monomers to a microtubule is quicker at which end?

Select one of the following:

  • The positive end

  • The negative end

Explanation

Question 4 of 22

1

Microtubules are more rigid than microfilaments.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 22

1

Is the positive or negative end of the microtubule embedded inside the centromere?

Select one or more of the following:

  • Positive (+)

  • Negative (-)

Explanation

Question 6 of 22

1

Microfilaments are a double helix of actin

Select one of the following:

  • True
  • False

Explanation

Question 7 of 22

1

A role of intermediate filaments is to provide strength and support to cells.

Select one of the following:

  • True
  • False

Explanation

Question 8 of 22

1

Intermediate filaments are:

Select one of the following:

  • Distributed broadly around the cell

  • Distributed only in specific areas of the cell

Explanation

Question 9 of 22

1

Microtubule motors are energy dependent (i.e. they require ATP.)

Select one of the following:

  • True
  • False

Explanation

Question 10 of 22

1

Which of these microtubule motors are minus end directed?

Select one of the following:

  • Dynein

  • Kinesin

Explanation

Question 11 of 22

1

Kinesin moves things towards the cell body/nucleus.

Select one of the following:

  • True
  • False

Explanation

Question 12 of 22

1

Which of the following statements are true regarding collagen:

i) it has a triple-helical structure
ii) collagen molecules run at right angles to each other
iii) there are approximately 20-40 variants
iv) collagen is made by ribosomes which are freely moving in the cytoplasm

Select one of the following:

  • if ii) and iii) are true

  • if ii), iii) and iv) are true

  • if i), ii) and iii) are true

  • if i) and iii) are true

Explanation

Question 13 of 22

1

Is elastin a highly hydrophobic or hydrophilic protein?

Select one of the following:

  • Hydrophobic

  • Hydrophilic

Explanation

Question 14 of 22

1

The extracellular matrix helps regulate cell differentiation

Select one of the following:

  • True
  • False

Explanation

Question 15 of 22

1

Tight junctions are which type of cell junction:

Select one of the following:

  • Occluding

  • Anchoring

  • Communicating

Explanation

Question 16 of 22

1

Tight junctions allow the specialisation of membranes.

Select one of the following:

  • True
  • False

Explanation

Question 17 of 22

1

Adheren junctions link to:

Select one of the following:

  • Actin Filaments

  • Microtubules

  • Intermediate Filaments

Explanation

Question 18 of 22

1

Desmosomes attach cells to the basal lamina.

Select one of the following:

  • True
  • False

Explanation

Question 19 of 22

1

Which molecule attaches desmosomes to each other?

Select one of the following:

  • Cadherins

  • Integrins

  • Claudins

  • Connexins

  • Selectins

Explanation

Question 20 of 22

1

Which molecule attaches tight junctions to each other?

Select one of the following:

  • Claudins

  • Cadherins

  • Intergrins

  • Connexins

  • Selectins

Explanation

Question 21 of 22

1

Which molecule attaches hemidesmosomes to the basal lamina?

Select one of the following:

  • Integrins

  • Cadherins

  • Claudins

  • Connexins

  • Selectins

Explanation

Question 22 of 22

1

Focal adhesions attach cells to the extracellular matrix by the use of:

Select one of the following:

  • Integrins and actin filaments

  • Cadherins and intermediate filaments

  • Integrins and intermediate filaments

  • Cadherins and actin filaments

Explanation

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