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Developmental Lecture 8 onwards

Question 1 of 12

1

A morphogen:

Select one of the following:

  • Is not expressed from a localised source in the embryo

  • Does not form a concentration gradient

  • Is not a signalling molecule

  • Specifies cell fates according to its concentration

Explanation

Question 2 of 12

1

Bicoid mRNA is tightly localised to the posterior end of the egg.

Select one of the following:

  • True
  • False

Explanation

Question 3 of 12

1

Which of the following is not an example of induction?

Select one of the following:

  • Xenopus animal cap assay

  • Homologous recombination

  • Anchor cell signalling to vulval precursors in the C.elegans embryo

Explanation

Question 4 of 12

1

In mosaic development, isolated cells are able to develop without external signalling.

Select one of the following:

  • True
  • False

Explanation

Question 5 of 12

1

Somites give rise to which of the following...? (Multiple answers)

Select one or more of the following:

  • Neural tube

  • Skeletal muscle

  • Notocord

  • Dermis

  • Glia

Explanation

Question 6 of 12

1

MyoD is sufficient to direct muscle development when transfected into non-muscle cells

Select one of the following:

  • True
  • False

Explanation

Question 7 of 12

1

Reverse genetics uses the mutant phenotype as a starting point

Select one of the following:

  • True
  • False

Explanation

Question 8 of 12

1

Which of the following are gain of function mutations...?

Select one or more of the following:

  • Amorph

  • Antimorph

  • Neomorph

  • Hypomorph

  • Hypermorph

Explanation

Question 9 of 12

1

Kit and Steel are in the same gene

Select one of the following:

  • True
  • False

Explanation

Question 10 of 12

1

Which of the following is the ligand-receptor pair Kit and Steel responsible for the normal development of...? (Multiple answers)

Select one or more of the following:

  • Melanoblasts

  • Keratinocytes

  • Germ cells

  • Fibrocytes

  • Megakaryocytes

  • Haematopoietic stem cells

Explanation

Question 11 of 12

1

Which one of the following is the correct Hh pathway sequence?

Select one of the following:

  • Hh ---| Ptc ---| Smo --> Ci ---> wg

  • Hh ---| Smo --> Ptc --> Ci ---| wg

  • wg ---> Ci ---> Ptc ---| Smo ---| Hh

  • wg ---| Smo ---| Ptc ---> Ci ---> Hh

Explanation

Question 12 of 12

1

Barchyury codes for a transcription factor responsible for the development of which germ layer?

Select one of the following:

  • Mesoderm

  • Ectoderm

  • Endoderm

Explanation

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