Common disorder of connective tissue and important cause of disability morbidity and mortality. Life expectant reduced by 4 years in men and 10 years in women. Western countries affect 1-3%. 3:1 female preponderance - greater in the young females, equal in the elderly. Disease is high during child bearing age but disease tend to go into remission during pregnancy High gravity (more children) adds protections against disease as does the pill.
Pinned to