Question 1
Question
How long is the complete maturation process for a RBC?
Answer
-
120 days
-
16-20 days
-
7 days
-
90 days
Question 2
Question
Erythropoeitin (EPO) initiates and stimulates production of RBCs
Question 3
Question
Which lab test shows the actual volume of RBCs in a unit of whole blood
Question 4
Question
Which lab test is useful in distinguishing between microcytosis anemia and hypochromia anemia?
Answer
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MCV
-
MCH
-
Reticulocyte count
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MCHC
Question 5
Question
When classifying anemia, first you look at the [blank_start]MCV[blank_end] test. If the result is high, then you have a [blank_start]macrocytic[blank_end] anemia and need to look at the [blank_start]Vitamin B12 and folate levels[blank_end] to determine if the anemia is [blank_start]Vitamin B12 deficiency[blank_end] or [blank_start]Folic acid deficiency[blank_end].
Question 6
Question
Microcytic anemias are caused by impaired Hct synthesis.
Question 7
Question
TIBC is decreased in iron deficiency.
Question 8
Question
Which lab test is the best indicator of iron deficiency or iron overload?
Answer
-
TIBC
-
Serum iron level
-
Ferritin
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% Transferrin Saturation
Question 9
Question
Iron is best absorbed on an empty stomach.
Question 10
Question
Body does not store much vitamin B12 so it is easy and quick to become vitamin B12 deficient.
Question 11
Question
Which of the following lab values are low in vitamin B12 deficiency?
Answer
-
MCV
-
Vitamin B12
-
Reticulocyte count
-
Hct
Question 12
Question
What types of foods have high folate levels?
Question 13
Question
Which anemia includes neurological manifestations?
Question 14
Question
How long are patients given folate for treatment of Folic Acid deficiency anemia?
Answer
-
1 week
-
2 months
-
4 months
-
1 year
Question 15
Question
Which of the following is a hemoglobin variant that causes manifestations of sickle cell disease when paired with HbS but does not when paired with itself?
Question 16
Question
At what age are people screened for sickle cell anemia
Answer
-
Before 18 years old
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Before 4 years old
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Before 2 years old
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Before 2 months old
Question 17
Question
How does hydroxyurea work?
Answer
-
Destroys HbS
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Stimulates production of HbF. HbF decreases polymer formation of HbS due to its high oxygen affinity
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Stimulates production of HbF. HbF decreases polymer formation of HbS due to its low oxygen affinity.
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Increases levels of HbA so there is a lower percentage of HbS in circulation
Question 18
Question
What should always be given with hydroyurea?
Answer
-
Vitamin B12
-
Folic acid
-
Iron
-
Normal RBCs
Question 19
Question
AJ is s 25 yo African American female who has sickle cell anemia and has had 2 severe pain crises in the past year. She is a good candidate for hydroxyurea.
Question 20
Question
If toxicity from hydroxyurea occurs, hydroxyurea should be D/C forever.
Question 21
Question
What is the only therapy that can cure sickle cell disease and should it be used for everyone?
Answer
-
Hydroxyurea; yes
-
Hydroxyurea; no
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HSCT; yes
-
HSCT; no
Question 22
Question
Which of the following sickle cell complications result in an acute decrease in Hgb with decreased reticulocyte count and transient suppression of RBC production in response to bacterial or viral infection?