11499951
Question 1
Question
The National Competent Authority BfArM is responsible for:
(more than one answer is correct)
Answer
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approval of substances
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approval of studies on medicial devices
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approval of studies on pharmaceuticals
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inspection of study sites
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inspections of animal space
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approval of genetic studies
Question 2
Question
The primary outcome of a First-in-Human study is always:
Answer
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Safety and tolerability
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Feasibility
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Pharmacodynamics
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Therapeutic effect
Question 3
Question
What is the main advantage of bipolar electrophysiological recordings, compared to a common reference?
Answer
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better spectral resolution
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better time resolution
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better spatial resolution
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higher amplification
Question 4
Question
Which answer is wrong?
The core features of schizophrenia include:
Answer
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Cognitive dysfunction
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Delusions and paranoia
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Social withdrawal
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Inflated sense of self importance
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Depressive episodes
Question 5
Question
The following are effective treatments for schizophrenia:
(more than one answer might be correct)
Answer
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antipsychotic medication
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stimulate medication
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cognitive behavior therapy (CBT)
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social skill training
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ECT
Question 6
Question
Question 6
Which of the following statements is true?
Answer
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The hyperdirect pathway involves the primary motor cortex and the subthalamic nucleus.
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The direct pathway is from the primary motor cortex directly to the GPi
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The main neurotransmitter of medium spiny neurons is glutamate.
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Dopamine is mainly produced in the substantia nigra pars reticulata.
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Striatal interneurons account for more than 90% of all striatal neurons.
Question 7
Question
Schizophrenia is a genetic disorder,
Answer
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but it is not heritable.
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and its heritability is around 80%.
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and environmental factors are not important.
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and its heritability is around 10%.
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but genetics factors are not associated with schizophrenia symptoms.
Question 8
Question
Which of these anatomic structures is not part of the basal ganglia?
Answer
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Corpus striatum
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Red nucleus
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Subthalamic nucleus
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Caudate nucleus
Question 9
Question
Which brain function is dominated most by one hemisphere?
Answer
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Hearing
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Language
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Vision
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Memory
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Smelling
Question 10
Question
Which study(ies) belong(s) to Phase I?
(more than one answer might be correct)
Answer
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Bioequivalence
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First in Human
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Pharmacokinetics in renal impairment
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Proof of concept
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Pharmacokinetic drug interaction
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