Neurologic and Neuromuscular Drugs

Description

Ahea 100 Pharmacology
Rebecca  Kaspers
Quiz by Rebecca Kaspers, updated more than 1 year ago
Rebecca  Kaspers
Created by Rebecca Kaspers over 6 years ago
21
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Resource summary

Question 1

Question
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Answer
  • True
  • False

Question 2

Question
Direct-acting skeletal muscle relaxants interfere with __________ ions involved in skeletal muscle contraction.
Answer
  • calcium
  • phosphorus
  • sodium
  • magnesium

Question 3

Question
Neuromuscular blocking drugs work by:
Answer
  • a. disrupting nerve impulses at motor end plates
  • b. disrupting nerve impulses at post-synaptic neurons
  • c. both the above are true

Question 4

Question
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Answer
  • True
  • False

Question 5

Question
The __________ is that area where a terminal nerve ending innervates a muscle.
Answer
  • a. motor end plate
  • b. synaptic cleft
  • c. both the above are true

Question 6

Question
Curare alkaloids:
Answer
  • Paralyze the diaphragm preventing breathing
  • Cross the blood-brain-barrier
  • Make one go unconscious immediately
  • Compete with phosphorus involved in muscle contraction

Question 7

Question
The antidote for curare alkaloids are __________ drugs.
Answer
  • anti-cholinesterase
  • cholinesterase

Question 8

Question
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Answer
  • True
  • False

Question 9

Question
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Answer
  • Longer muscle paralysis
  • Shorter muscle paralysis
  • Succinylcholine has nothing to do with muscle paralysis

Question 10

Question
Parkinson’s disease:
Answer
  • a. has a deficiency of dopamine
  • b. has an excess of acetylcholine
  • c. is a movement disorder
  • d. all the above are true

Question 11

Question
Akinesia is the absence of:
Answer
  • the power of voluntary movement
  • the ability to think
  • diaphragmatic movement
  • the ability of speech

Question 12

Question
The 2 types of therapy for Parkinson’s disease are __________ and __________ drugs.
Answer
  • anti-cholinergic; dopaminergic
  • anti-cholinergic; anti-cholinesterase
  • cholinergic; dopaminergic
  • cholinergic; anti-cholinesterase

Question 13

Question
Another name for anti-cholinergic drugs is __________ drugs.
Answer
  • parasympatholytic
  • sympatholytic

Question 14

Question
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Answer
  • True
  • False

Question 15

Question
Dopaminergic drugs act on the brain to improve motor function.
Answer
  • True
  • False

Question 16

Question
Levodopa can convert to dopamine:
Answer
  • before crossing the blood-brain-barrier
  • after crossing the blood-brain-barrier
  • both the above are true

Question 17

Question
COMT inhibitors are reversible.
Answer
  • True
  • False

Question 18

Question
Triptans are used to treat:
Answer
  • musculoskeletal issues
  • migraines
  • seizures
  • Parkinson’s disease

Question 19

Question
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Answer
  • migraines
  • musculoskeletal issues
  • seizures
  • Parkinson’s disease

Question 20

Question
Abortive anti-migraine drugs are designed to stop a migraine:
Answer
  • a. after it starts
  • b. before it starts
  • c. both the above are correct
  • d. neither of the above are correct
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