Question 1
Question
Fill in the blanks to describe the classifications of epithelial tissues by the shape of their cells.
[blank_start]Squamous[blank_end] epithelium has cells wider than their height that often provide a protective layer.
[blank_start]Cuboidal[blank_end] epithelium has cells with approximately the same width and height that are often found in the glands.
[blank_start]Columnar[blank_end] epithelium has cells with a greater height than their width that are specialised for absorption and secretion.
Answer
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Squamous
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Cuboidal
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Columnar
Question 2
Question
What name is given to epithelial tissue where the cells appear to be arranged in multiple layers but each has an attachment to the basement membrane?
Answer
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Stratified
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Pseudostratified
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Quasistratified
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Fraudostratified
Question 3
Question
Keritinized epithelium has a layer of dead cells full of keratin upon it.
Question 4
Question
Epithelial cells have fixed shapes to maintain their function.
Question 5
Question
In what system do we find transitional epithelium in particular?
Answer
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Urinary system
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Renal system
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Respiratory system
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Gastrointestinal system
Question 6
Question
Which statement accurately describes an exocrine gland?
Answer
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Secretes substances to a free surface by means of a duct
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Secretes hormones into the bloodstream
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Secretes substances to the skin only
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Secretes enzymes only
Question 7
Question
Blood vessels can penetrate the basal membrane.
Question 8
Question
FIll in the blanks to describe the development of an exocrine gland.
1. Cells [blank_start]proliferate[blank_end] down into the connective tissue.
2. The primitive gland remains attached to the epithelium via a [blank_start]stalk[blank_end].
3. The cells of the stalk [blank_start]differentiate[blank_end] to form ductal cells.
Answer
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proliferate
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stalk
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differentiate
Question 9
Question
Endocrine cells follow a similar development to exocrine glands - their cells proliferate down into the connective tissue from the epithelium. However, what happens after this?
Answer
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Blood vessels penetrate between cells to obstruct the connecting cells
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Blood vessels penetrate the basal membrane to form cords of cells forming the glands
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The cells of a stalk connecting the gland to the epithelium differentiate into ductal cells
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The proliferated cells develop into blood vessels
Question 10
Question
Fill in the blanks to define the different types of exocrine secretion.
[blank_start]Merocrine[blank_end] secretion is where vesicles containing the secretory substance fuse with the surface membrane in regular exocytosis.
[blank_start]Apocrine[blank_end] secretion is where part of the apical cytoplasm is lost together with the secretory product as a vesicle forms at this membrane.
[blank_start]Holocrine[blank_end] secretion is where the entire cell breaks down to discharge the secretory substance.
Answer
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Merocrine
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Apocrine
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Holocrine
Question 11
Question
Cell junctions are multiprotein complexes that provide contact between neighbouring cells.
Question 12
Question
Which junction seals neighbouring cells together in an epithelial sheet in order to prevent leakage of molecules between them?
Answer
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Tight junction
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Adherens junction
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Desmosome
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Gap junction
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Hemidesmosome
Question 13
Question
Adherens junctions join bundles of which molecule in one cell to a similar bundle in a neighbouring cell?
Answer
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Actin
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Myosin
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Intermediate filaments
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Integrin
Question 14
Question
Which cell junction joins the intermediate filaments in one cell to those of a neighbour?
Answer
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Tight junction
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Adherens junction
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Desmosome
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Gap junction
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Hemidesmosome
Question 15
Question
What is the function of gap junctions?
Answer
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Allows passage of small water-soluble ions and molecules between cells
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Allows passage of water into or out of the cell
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Contributes to maintenance of resting membrane potential
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Anchor cells to the basal lamina
Question 16
Question
Hemidesmosomes anchor intermediate filaments in a cell to the basal lamina.
Question 17
Question
Tight junctions consist of a continuous band of homodimer proteins at the basal edge of a cell.
Question 18
Question
What is the function of adherens junctions>?
Answer
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Maintains cell shape
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Prevents passage of soluble molecules between cells
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Allows passage of soluble molecules through cells
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Anchors epithelial tissue to the basal membrane
Question 19
Question
Label this diagram to show some of the proteins involved in an adherens junction.
Question 20
Question
Which proteins are linked to the cytoskeleton in the formation of tight junctions? Check all that apply.
Answer
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Occludin
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Claudin
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Actin
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Cadherin
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Catenin
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Connexin
Question 21
Question
Why is it that desmosomes and hemidesmosomes anchor to the intermediate filaments of a cell, considering they have a structural function?
Answer
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Intermediate filaments are static and rigid whereas actin is motile
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Intermediate filaments are present in all cells whereas other components of the cytoskeleton are not
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Intermediate filaments are in higher abundance in cells than the other components of the cytoskeleton
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Intermediate filaments are not influenced by changes in temperature or pH
Question 22
Question
Cell adhesion proteins in desmosomes bind homophilically. What does this mean?
Answer
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Same protein in one cell binds to identical protein on another
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Certain protein in one cell binds to different protein on another
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Proteins are attracted to water which is required for binding
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Proteins are attracted to cell membrane proteins
Question 23
Question
How many connexon proteins make up the ring in a gap junction?
Question 24
Question
Gap junctions are always open.
Question 25
Question
Integrin proteins are involved in the formation of which cell junction?
Answer
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Tight junctions
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Adherens junctions
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Gap junctions
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Desmosomes
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Hemidesmosomes