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The Adaptive Immune System

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Infection and Immunity Quiz on The Adaptive Immune System , created by m p on 15/06/2015.
m p
Quiz by m p, updated more than 1 year ago
m p
Created by m p over 9 years ago
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Resource summary

Question 1

Question
What triggers the activation of the adaptive immune system?
Answer
  • Pathogen exposure
  • Inflammation
  • Antibody production
  • Phagocytosis

Question 2

Question
There are two components of the adaptive immune system. What are they called?
Answer
  • Cellular immune system
  • Humoral immune system
  • Antigenic immune system
  • Cytotoxic immune system
  • Acquired immune system

Question 3

Question
What happens to the response of the immune system on each repeated exposure to a pathogen?
Answer
  • It becomes faster
  • It becomes more specific
  • It causes more inflammation
  • It becomes less efficient
  • It involves more components of the immune system

Question 4

Question
What cells are involved in humoral immunity?
Answer
  • B cells
  • T cells
  • Natural killer cells
  • Phagocytes

Question 5

Question
What cells are involved in cellular immunity?
Answer
  • B cells
  • T cells
  • Phagocytes
  • Natural killer cells

Question 6

Question
Which part of the adaptive immune system produced antibodies?
Answer
  • Humoral
  • Cellular
  • Both

Question 7

Question
The adaptive immune system is able to remember pathogens in case they present again. True or false?
Answer
  • True
  • False

Question 8

Question
Which cells express CD4?
Answer
  • T helper cells
  • T killer cells
  • T regulatory cells
  • Plasma B cells

Question 9

Question
What is the function of T helper cells?
Answer
  • Activate macrophages
  • Help B cells to produce antibodies
  • Remember the pathogen in case of repeat infection
  • Produce antibodies
  • Activate natural killer cells

Question 10

Question
Why do we need T regulatory cells?
Answer
  • To control the immune response
  • To ensure the immune response is specific
  • To prevent the immune system from attacking healthy cells
  • To prevent the immune system from attacking normal flora

Question 11

Question
Which cells expressed CD8?
Answer
  • T killer cells
  • T helper cells
  • T regulatory cells
  • Plasma B cells

Question 12

Question
Which cells have the longest life-span?
Answer
  • T regulatory cells
  • Memory B cells
  • Plasma B cells
  • T helper cells

Question 13

Question
How are antibodies separated into classes?
Answer
  • By their heavy chain
  • By their light chain
  • By their constant region
  • By their variable region
  • By what sort of pathogen they are against

Question 14

Question
What is the function of membrane bound antibodies?
Answer
  • Recognise antigens
  • Activate B cells
  • Activate T cells
  • Opsonisation
  • Neutralization of pathogens

Question 15

Question
Which type of antibody activates complement?
Answer
  • Membrane bound antibodies
  • Secreted antibodies

Question 16

Question
Which cells require an antigen presenting cell to activate them?
Answer
  • T cells
  • B cells

Question 17

Question
Which of the following cells can act as antigen presenting cells?
Answer
  • Dendritic cells
  • Macrophages
  • Natural killer cells
  • Plasma B cells
  • Mast cells

Question 18

Question
Which cells express MHCI?
Answer
  • All nucleated cells
  • T helper cells
  • Antigen presenting cells
  • Plasma B cells
  • Natural killer cells

Question 19

Question
Which of the following cells recognised MHCII?
Answer
  • CD8 cells
  • CD4 cells

Question 20

Question
Where within the antigen presenting cell is the MHC produced?
Answer
  • Endoplasmic reticulum
  • Golgi body
  • Ribosome
  • Nucleus

Question 21

Question
Where is the MCHII complex combined with the antigenic peptides?
Answer
  • Endosome
  • Endoplasmic reticulum
  • Golgi body
  • Vesicle

Question 22

Question
The T cell is activated when it detects the MHC-antigen complex. True or false?
Answer
  • True
  • False

Question 23

Question
Which types of hypersensitivity reaction are mediated by antibodies?
Answer
  • I
  • II
  • III
  • IV

Question 24

Question
Which type of hypersensitivity reaction is mediated by IgE?
Answer
  • I
  • II
  • III
  • IV

Question 25

Question
Which of the following are examples of hypersensitivity reactions that are mediated by IgE?
Answer
  • Asthma
  • Pollen allergy
  • SLE
  • Myasthenia Gravis
  • Grave's disease
  • Type I diabetes
  • Psoriasis

Question 26

Question
In a type I hypersensitivity reaction, what needs to happen to the antibodies on repeat exposure for there to be a hypersensitivity reaction?
Answer
  • Clonal expansion
  • Cross-linking
  • Breaking of the disulphide bonds
  • Dimer formation

Question 27

Question
Grave's disease is an example of a type II hypersensitivity reaction. What are type II hypersensitivity reactions mediated by?
Answer
  • IgE
  • Antibodies other than IgE
  • T helper cells
  • T cytotoxic cells
  • Natural killer cells

Question 28

Question
What is another example of a type II hypersensitivity reaction?
Answer
  • Myasthenia Gravis
  • Asthma
  • Type I diabetes
  • SLE
  • Coeliac disease

Question 29

Question
How do the antibodies in type II hypersensitivity reactions cause disease?
Answer
  • They block the receptor
  • They activate the receptor
  • They destroy the receptor
  • They act as inverse agonists

Question 30

Question
In which type of hypersensitivity reaction after immune complexes formed?
Answer
  • I
  • II
  • III
  • IV

Question 31

Question
Why are immune complexes a problem?
Answer
  • Because they can get stuck in the body
  • Because they promote autoimmune destruction of cells
  • Because they promote other hypersensitivity reactions
  • Because they increase the viscosity of blood which can cause thrombosis
  • Because they cause lymphadenopathy

Question 32

Question
Antibodies in immune complexes can activate complement. True or false?
Answer
  • True
  • False

Question 33

Question
What are type IV hypersensitivity reactions mediated by?
Answer
  • T helper cells
  • Antibodies other than IgE
  • IgE
  • T killer cells

Question 34

Question
Which of the following are examples of type IV hypersensitivity reactions?
Answer
  • Coeliac disease
  • Type I diabetes
  • SLE
  • Asthma
  • Haemolytic disease of the new born

Question 35

Question
How do T helper cell cause hypersensitivity reactions?
Answer
  • Cytokine production that activates macrophages and T cytotoxic cells
  • Activation of natural killer cells
  • Activation of mast cells causing release of histamine
  • Formation of immune complexes which activate complement
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