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Question 1
Question
How do loop diuretics work?
Answer
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Inhibit Na+ reabsorption in the early diluting segment of the distal tubule
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block sodium bicarbonate reabsorption
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increase filtrate osmolarity
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Inhibit the 3-ion co-transporter (Na-K-2Cl co-transporter)
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Bind to and inhibit Na+/Cl co-transporter
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