Question 1
Question
Which options are primary lymphoid organs?
Answer
-
Thymus
-
Bone marrow
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Spleen
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Peyer's patches
-
MALT
Question 2
Question
Which options are secondary lymphoid organs?
Answer
-
MALT
-
Spleen
-
Lymph nodes
-
Thymus
-
Bone marrow
Question 3
Question
Dendritic cells are derived from lymphoid and myeloid precursors.
Question 4
Question
Platelets are derived directly from pluripotent stem cells.
Question 5
Question
Which options do not express MHC Class 1?
Answer
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Red blood cells
-
Platelets
-
Neutrophils
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B cells
-
T cells
Question 6
Question
Naive B cells are derived from the
Answer
-
Bone marrow
-
Thymus
-
Spleen
-
MALT
Question 7
Question
CD4+ T cells recognise
Question 8
Question
CD8+ T cells recognise
Question 9
Question
CD16 and CD56 are both found on
Answer
-
NK cells
-
Macrophages
-
B cells
-
T cells
Question 10
Question
All leukocytes express
Question 11
Question
The most abundant leukocyte in circulation are...
Answer
-
Neutrophils
-
Macrophages
-
B cells
-
CD8+ T cells
Question 12
Question
Monocytes and Macrophages help to produce components involved in the complement system
Question 13
Question
Macrophages are able to present antigens on their surface
Question 14
Question
Monocytes have CD.....
Question 15
Question
During phagocytosis, fusion of the lysosome and phagosome leads to production of...
Answer
-
Phagolysosome
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Early endosome
-
Endophagosome
Question 16
Question
Which granulocytes have major basic protein in their granules?
Answer
-
Eosinophils
-
Basophils
-
Neutrophils
Question 17
Question
Which granulocytes have lactoferrin in their granules?
Answer
-
Neutrophils
-
Eosinophils
-
Basophils
Question 18
Question
Which granulocytes do not have histamine in their granules?
Answer
-
Eosinophils
-
Neutrophils
-
Basophils
Question 19
Question
Which granulocytes have chondroitin sulphate in their granules?
Answer
-
Neutrophils
-
Eosinophils
-
Basophils
Question 20
Question
Which of these are reactive oxygen species?
Answer
-
Hypochlorous acid
-
Hydrogen peroxide
-
Superoxide
-
Water
Question 21
Question
The only antimicrobial peptides that macrophages use are...
Answer
-
Cathelicidins
-
Azurocidin
-
Defensins
-
Histatins
Question 22
Question
Acidification by neutrophils or macrophages is...
Answer
-
Bacteriocidal
-
Bacteriostatic
-
Can be both
Question 23
Question
Both macrophages and neutrophils produce ROS's.
Question 24
Question
Both macrophages and neutrophils produce NETs.
Question 25
Question
The most potent antigen present cell is...
Answer
-
Dendritic cells
-
Macrophages
-
Monocytes
-
B cells
Question 26
Question
Label the features of platelets
Answer
-
platelet
-
ctivating
-
fibrinogen
-
ytokines
-
C3b
Question 27
Question
Most T cells are...
Answer
-
CD4 positive but CD8 negative
-
CD4 positive and CD8 positive
-
CD8 positive but CD4 negative
Question 28
Question
Which cytokine results in a T cell receptor being produced on an immature T cell?
Question 29
Question
Self molecules are said to induce...
Answer
-
Tolerance
-
Multi-specificity
-
Immunogenicity
Question 30
Question
What is negative selection?
Answer
-
T cells with a high affinity for self antigens are killed by apoptosis
-
T cells with a high avidity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are killed by apoptosis
-
T cells with a low affinity for self antigens are allowed to mature
Question 31
Question
What is positive selection?
Answer
-
T cells with a low affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are allowed to mature
-
T cells with a high affinity for self antigens are killed off by apoptosis
-
T cells with a low affinity for self antigens are killed off by apoptosis
Question 32
Question
The majority of T cells do not make it through negative selection.
Question 33
Question
T cells without any stimulation also die off.
Question 34
Question
What CD do T regulatory cells have?
Question 35
Question
Which cells do TH1 helper cells activate?
Answer
-
Macrophages
-
B cells
-
Any nucleated cell
-
Stromal cells
Question 36
Question
Which cells do TH2 helper cells activate?
Answer
-
B cells
-
Macrophages
-
T cells
-
Stromal cells
Question 37
Question
Which cells do TH17 helper cells activate?
Answer
-
Stromal cells
-
B cells
-
Macrophages
-
T cells
Question 38
Question
What is the main effect of T reg cells?
Question 39
Question
What is the main effect of TH2 cells?
Question 40
Question
What is the main effect of TH1 cells?
Question 41
Question
What is the main effect of TH17 cells?
Question 42
Question
Which cytokine(s) tend to be released by TH17 cells?
Answer
-
IL-7
-
IL-17
-
TGF-beta
-
IL-10
Question 43
Question
Which cytokine(s) tend to be released by TH1 cells?
Answer
-
IL-7
-
IL-10
-
IFN-gamma
-
TGF-beta
Question 44
Question
Which cytokine(s) tend to be released by TH2 cells?
Question 45
Question
Which cytokine(s) tend to be released by CD8+ cells?
Answer
-
IFN-gamma
-
TNF-a
-
TGF-b
-
IL-4
Question 46
Question
What feature on T cells helps to induce proliferation B cells?
Answer
-
CD40
-
CD40 Ligand
-
mIgM
-
CD45
Question 47
Question
B cells have complement receptors.
Question 48
Question
As well as perforin and granzyme to kill target cells, NK cells have...
Answer
-
NK Cytotoxic factor
-
CD40 Ligand
-
Major basic protein
-
Lyophosphatase
Question 49
Question
Interferon gamma is produced by NK cells - what is its function?
Question 50
Question
NK cells have a T cell receptor.
Question 51
Question
T cells are the most abundant lymphocytes.