Healing and Repair Part 2

Wound edges are not opposed in healing by

Which type of healing involves more granulation tissue?

Wound edges are opposed in what type of healing?

Which protein acts as a framework for cell growth during primary intention?

Surface dehydration of a wound results in...

As the blood clot disappears during healing by primary intention, what feature forms?

Healing by primary intention: The wound edges are brought close together so that there is a narrow incision. The wounded area fills with a [blank_start]blood clot[blank_end] which has a [blank_start]fibrin[blank_end] mesh that acts as a framework for cell growth. The surface of the wound dehydrates which forms a [blank_start]scab[blank_end]. There is [blank_start]acute[blank_end] inflammation around the edges of the wound. The epidermis thickens and grows along the cut edge of the dermis to meet in the midline. [blank_start]Granulation[blank_end] tissue grows into the blood clot that filled the wound space and this produces a [blank_start]dermal[blank_end] scar.

The inflammatory reaction is less intense in healing by primary intention.

Wound contraction is higher in wounds healing by secondary intention.

Wound contraction is due to cells specifically known as...

If a wound is infected, surgeons will...

Healed wounds eventually become as strong as normal skin.

Healed wounds don't get any stronger after approximately...

Healed wounds get stronger because of...

Areas that have a greater blood supply will generally heal

Vitamin C deficiency interferes with

Moving a wound early on while it is healing can delay healing.

Wound dehiscence is an example of

Keloid scarring is an example of

Exuberant granulations occur when...

Aggressive fibromatoses are due to...

Which type of problem to do with wound repair is considered nearly malignant?

Label the diagram

Cytokines released in wound healing are similar to those in bone healing.

A bone fracture disrupts blood vessels. This results in...

Osteoblasts which help to deposit bone and repair fractures are sourced from where?

Deposition of the uncalcified matrix during bone healing anchors the bone ends but [blank_start]does not[blank_end] give structural rigidity. This is known as the [blank_start]soft[blank_end] tissue callus. When [blank_start]woven[blank_end] bone is deposited this forms teh [blank_start]bony[blank_end] callus and structural rigidity increases with time to allow weight to be put on the bone. Eventually the [blank_start]bony[blank_end] callus is remodelled and woven bone is replaced by [blank_start]lamellar[blank_end] bone with the m[blank_start]edullary[blank_end] cavity being restored (bone marrow chamber).

The soft tissue callus is associated with

Select the statement that is true

Uncalcified bone matrix is also known as...

Select the correct order from fracture to the healing of a bone fracture.

Woven bone is a similar strength to lamellar bone.

Bone healing is quicker in

Problems with bone healing: D[blank_start]eformity[blank_end] - due to malalignment when repositioning fracture Soft tissue getting in between broken bone Delayed union progressing to [blank_start]Non[blank_end]-union - fracture ends keep moving Pseudo[blank_start]arthrosis[blank_end] - [blank_start]synovial[blank_end] cavity at the site of the fracture Avascular [blank_start]necrosis[blank_end] - death of a section of bone due to is[blank_start]chaemia[blank_end] Osteo[blank_start]myelitis[blank_end] - especially in open fractures