Factors Affecting Enzyme Activity

The main reason why rate of enzyme action increases with temperature initially is...

The level of a condition at which enzymes work best is called the [blank_start]optimum[blank_end] temperature/pH/etc.

Why do enzymes work less effectively in extreme pH, or in very high temperatures?

The optimum temperature for enzymes in the human body is 37 degrees C.

Rate of reaction is proportional to..

There is a [blank_start]positive[blank_end] correlation between substrate concentration and initial rate of reaction. However, past a point, the graph [blank_start]plateaus[blank_end]. This is because of [blank_start]a limiting factor[blank_end], which is the [blank_start]enzyme concentration[blank_end]. At this point and beyond, the enzymes are said to be [blank_start]saturated[blank_end].

Cells create one set of enzymes that last for the duration of the cell's life.

Inhibitors that [blank_start]block[blank_end] the [blank_start]active site[blank_end] of enzymes are [blank_start]competitive[blank_end], whereas inhibitors that [blank_start]change[blank_end] the [blank_start]shape[blank_end] of enzymes are [blank_start]non-competitive[blank_end].

Label the enzyme inhibition diagram.

Which of the following statements are true about end product inhibition? Select all that apply.

[blank_start]Potassium cyanide[blank_end] is an inhibitor that is also a metabolic poison. In the body, it forms [blank_start]hydrogen cyanide[blank_end]. The [blank_start]cyanide[blank_end] ions bind [blank_start]irreversibly[blank_end] to [blank_start]mitochondria[blank_end] and prevent normal [blank_start]aerobic respiration[blank_end]. Snake venom contains [blank_start]acetylcholinesterase[blank_end], which prevents the breakdown of [blank_start]acetylcholine[blank_end], thereby preventing muscle relaxation. Various therapeutic drugs are available that work by inhibiting enzymes such as [blank_start]ACE[blank_end], [blank_start]proteases[blank_end], and [blank_start]ATPase[blank_end].