Pregunta 1
Pregunta
T or F. African Americans respond better to a Thiazide diuretic.
Pregunta 2
Pregunta
T or F. Beta blockers are 1st line drugs for HTN.
Pregunta 3
Pregunta
Select all that apply. Which of the following are thiazide diuretics.
Respuesta
-
HCTZ
-
Indapamide
-
Lasix
-
Spironolactone
-
Metolazone
Pregunta 4
Pregunta
Which class of diuretics inhibits distal convoluted tubule sodium and chloride re-absorption?
Respuesta
-
Loop
-
Potassium Sparing
-
Potassium Wasting
Pregunta 5
Pregunta
Select all that apply. Which of the following electrolyte imbalances can occur with thiazide diuretics?
Respuesta
-
Hypokalemia
-
Hypehalemia
-
Hypercalcemia
-
Hypocalcemia
-
Hyponatremia
-
Hypernatremia
-
Hypomagnesemia
-
Hypermagnesemia
Pregunta 6
Pregunta
Chlorthalidone and indapamide, are longer acting thiazide diuretics, more potent than HCTZ and carry a higher risk for hypokalemia.
Pregunta 7
Pregunta
A dose of HCTZ greater than _____mg has an increased risk for hypokalemia.
Pregunta 8
Pregunta
What should the NP monitor when a patient is on thiazide diuretics? Select all that apply.
Respuesta
-
BUN
-
Serum Creatinine or CrCl
-
Heart rate
-
Blood pressure
-
Vision changes
-
Electrolytes
Pregunta 9
Pregunta
T or F. Thiazide diuretics are commonly combined with other anti-hypertensives.
Pregunta 10
Pregunta
T or F. Thiazide diuretics are contraindicated in persons with gout as they increase uric acid.
Pregunta 11
Pregunta
T or F. Loop diuretics are used more often for edema than HTN.
Pregunta 12
Pregunta
The following are exemplar Loop Diuretics:
Respuesta
-
Lasix
-
HCTZ
-
Lisinopril
-
Bumetanide
-
Indapamide
-
Metolazone
-
Toresemide
Pregunta 13
Pregunta
Identify the MOA for loop diuretics from the choices below:
Respuesta
-
Inhibits distal convoluted tubule Na+ and Cl reabsorption
-
Inhibits Loop of Henle and proximal/distal convoluted tubule Na+ and Cl reabsorption
-
Stops the conversion of Angiotensin I to Angiotensin II
Pregunta 14
Pregunta
Loop diuretics are contraindicated in patients with:
Respuesta
-
Shellfish allergies
-
Sulfa allergies
-
Diabetes
-
Edema
Pregunta 15
Pregunta 16
Pregunta
T or F. Potassium Sparing Diuretics have weak diuretic activity.
Pregunta 17
Pregunta
Exemplars of Potassium Sparing Diuretics Includes: (select all that apply)
Respuesta
-
Triameterene
-
Lasix
-
Bumentanide
-
Spironalactone
-
HCTZ
-
Eplerenone
Pregunta 18
Pregunta 19
Pregunta
Lisinopril should be d/c if serum K+ increases more than?
Pregunta 20
Pregunta
Which ACE is not used often for maintenance therapy d/t a short half-life and multiple dosing?
Respuesta
-
Benazepril
-
Catorpil
-
Lisinopril
-
Ramipril
Pregunta 21
Pregunta
If a patient is at high risk for renal artery stenosis, how soon after initiating ACEI should the patient's Cr be checked?
Respuesta
-
1 week
-
1 month
-
48 hours
-
3-5 days
Pregunta 22
Pregunta
Which patient populations have a greater risk of developing angioedema with the use of ACEI? Select all that apply.
Respuesta
-
Asian
-
Latino
-
Pacific Islander
-
Caucasian
-
African American
Pregunta 23
Pregunta
ACEI therapy is preferred for the following populations (select all that apply):
Pregunta 24
Pregunta
ACEI and ARBS can have the following additional positive effects (select all that apply):
Respuesta
-
Improve oxygenation to the heart
-
Decrease inappropriate remodeling of heart muscle after MI
-
Reduce effects of diabetes on the kidneys
-
Improve insulin sensitivity
-
All of the Above
Pregunta 25
Pregunta
What is a possible inconvenient but not life threatening adverse reaction from ACEI therapy?
Pregunta 26
Pregunta
ACEI can increase K+
Pregunta 27
Pregunta
An increase in Cr with ACEI therapy is often transient.
Pregunta 28
Pregunta
What is the most common adverse reaction to ACEI therapy?
Respuesta
-
SOB
-
Hypotension
-
Bradycardia
-
Fever
Pregunta 29
Pregunta
The following are exemplars for ARBS (select all that apply)
Respuesta
-
Lisinopril
-
Losartan
-
Amlodipine
-
Valsartan
-
Verapamil
-
Olmesartan
Pregunta 30
Pregunta
ARBS prevent the binding of Angiotensin II to receptors in the kidneys, brain, heart and arterial walls-inhibit RAAS and cause fall in peripheral resistance.
Pregunta 31
Pregunta
ARBS may never be combined with which class of drug?
Respuesta
-
Thiazide diuretics
-
ACEI
-
CC Blockers
-
Direct Renin Inhibitors
Pregunta 32
Pregunta
ACEI and ARBS should be avoided in:
Pregunta 33
Pregunta
ARBS can be a good choice for patients with Gout because:
Pregunta 34
Pregunta
T or F. ARBS can raise serum K+.
Pregunta 35
Pregunta
The Direct Renin Inhibitor Tekturna shares this possible side effect with ACEI.
Respuesta
-
Increased WBG
-
Angioedema
-
Cough
-
Decreased K+
Pregunta 36
Pregunta
T or F. Tekturna can increase serum K+.
Pregunta 37
Pregunta
T or F. ARBS are contraindicated in patients with Renal Artery Stenosis.
Pregunta 38
Pregunta
T or F. You can combine ACEI, ARBS and DRI.
Pregunta 39
Pregunta
The following is true of dihydropyridine CCB (select all that apply):
Respuesta
-
Are potent vasodilators that lower calcium influx into the smooth muscle.
-
Have little or no negative effect on cardiac contractility and conduction.
-
Can treat chronic stable angina
-
Can be used in patients with CHF
Pregunta 40
Pregunta
Dihyropyridine CCB include (select all that apply)
Respuesta
-
Norvasc
-
Losartan
-
Nifedipine
-
Benazepril
-
Felodipine
Pregunta 41
Pregunta
T or F. Peripheral edema can be caused by amlodipine.
Pregunta 42
Pregunta
Which class of drugs can be combined with Amlodipine to reduce peripheral edema?
Respuesta
-
ARBS
-
DRI
-
ACES
-
Thiazide Diuretics
Pregunta 43
Pregunta
Dihyrdopyridine CCB have greater efficacy in African Americans.
Pregunta 44
Pregunta
T or F. ACEI can never be prescribed to African Americans.
Pregunta 45
Pregunta
The following is true of non-dihyrdopyridine CCB (select all that apply):
Respuesta
-
Can treat A-fib
-
Can be effective in proteinuria reduction.
-
Have a depressive effect on cardiac contractility and conduction
-
Should be avoided in patients who are taking beta blockers
Pregunta 46
Pregunta
T or F. Verapamil has the strongest inotropic effect of the non-dihyrdopyridine CCB and should be avoided in patients with Heart Failure.
Pregunta 47
Pregunta
Verapamil can interact with the following (select all that apply):
Respuesta
-
Simvastatin
-
Lithium
-
Amiodarone
-
Codeine
-
Spironalactone
Pregunta 48
Pregunta
T or F. Beta blockers are 1st line in the treatment of HTN.
Pregunta 49
Pregunta
Cardio-selective beta-blockers include (select all that apply):
Respuesta
-
Atenolol
-
Metropolol
-
Coreg
-
Propranolol
-
Bisoprolol
-
Esmolol
-
Acebutolol
Pregunta 50
Pregunta
Propranolol is a non-cardioselective beta-blocker that is used for symptom management with which endocrine issue:
Respuesta
-
Hypothyroidism
-
Hyperthyroidism
Pregunta 51
Pregunta
T or F. CCB and Beta-blockers can used for prophylactic treatment of migraines.
Pregunta 52
Pregunta
T or F. Beta-blockers are superior protection against stroke.
Pregunta 53
Pregunta
An example of mixed alpha and beta blocker is:
Respuesta
-
Carvedilol (coreg)
-
Nadolol
-
Atenolol
-
Propranolol
Pregunta 54
Pregunta
What is major consideration when prescribing a beta-blocker in a patient with DM?
Pregunta 55
Pregunta
In a patient with decompensated bronchospastic disease with stable angina, the NP should prescribe:
Pregunta 56
Pregunta
S/E of beta-blockers can include (select all that apply):
Pregunta 57
Pregunta
T or F. Discontinuation of beta-blockers needs to occur over a few weeks.
Pregunta 58
Pregunta
Clonodine belongs to which class of anti-hypertensives?
Respuesta
-
ACEI
-
DRI
-
Beta-blockers
-
Centrally Acting Agents
Pregunta 59
Pregunta
Centrally acting agents can be used to treat which condition in pediatric patients.
Respuesta
-
Depression
-
Dry Mouth
-
ADHD
-
Dizziness
Pregunta 60
Pregunta
Possible Adverse Reactions to Centrally Acting Agents includes (select all that apply):
Respuesta
-
Fatigue
-
Dry mouth
-
Lightheadedness
-
Rash
-
Hypoglycemia
-
Bradycarida
Pregunta 61
Pregunta
T or F. Patients wanting to come off of clonidine need to be tapered due to risk for rebound HTN.
Pregunta 62
Pregunta
Methyldopa is indicated in which population?
Respuesta
-
Elderly
-
Pregnant women
-
Adolescents
-
African Amercians
Pregunta 63
Pregunta
A contraindication for Methyldopa is:
Respuesta
-
Kidney Disease
-
DM
-
CHF
-
Active Hepatic Disease
Pregunta 64
Pregunta
T or F. The MOA of methyldopa is it stimulates the Alpha 2 adrenergic receptors.
Pregunta 65
Pregunta
Prazosin a peripherally acting agent, while not a 1st line anti-hypertensive is effective in treating:
Pregunta 66
Pregunta
T or F. Doxazosin should be taken at bedtime due to risk for postural lightheadedness.
Pregunta 67
Pregunta
The following should be avoided in pregnancy (select all that apply):
Respuesta
-
ACEI
-
ARBS
-
Direct Renin Inhibitors
-
Sprionolactone
-
Eplerenone
-
Methyldopa
Pregunta 68
Pregunta
In addition to methyldopa, which two other drugs are commonly used for HTN in pregnancy:
Pregunta 69
Pregunta
T or F. Betablockers are not recommended as initial therapy in children.
Pregunta 70
Pregunta
Which class of diuretics is used in fluid volume overload?
Respuesta
-
Thiazide
-
Potassium Sparing
-
Loop
-
HCTZ
Pregunta 71
Pregunta
When using Digoxin to treat Stage C Heart Failure, the NP knows which medicine can upset the narrow therapeutic index of the drug:
Respuesta
-
Diltiazem
-
Benazapril
-
Spironolactone
-
ASA
Pregunta 72
Pregunta
T or F. Digoxin increases myocardial contractility.
Pregunta 73
Pregunta
The therapeutic index for digoxin is:
Respuesta
-
0.10-0.20
-
0.1-0.3
-
0.5-0.9
-
0.3-0.8
Pregunta 74
Pregunta
T or F. Low K+ and Mg+ and high Ca+ increase the risk for digoxin toxicity.
Pregunta 75
Pregunta
Signs of toxicity to tell your patient who is taking digoxin are (select all that apply):
Pregunta 76
Pregunta
HMG CoA reductase inhibitors are more commonly known as:
Respuesta
-
Statins
-
ARBS
-
Fibrates
-
Omega 3 Fatty Acids
Pregunta 77
Pregunta
The primary treatment goal of statins is to:
Respuesta
-
Increase LDL
-
Increase HDL
-
Decrease LDL
-
Increase Liver Function
Pregunta 78
Pregunta
T or F. It is fine for pregnant women or women planning to become pregnant to take simvastatin.
Pregunta 79
Pregunta
Which group of patients could benefit from statins:
Pregunta 80
Pregunta
Statins should be discontinued if which lab value if it is >3x the normal value?
Pregunta 81
Pregunta
There is an increased risk of myopathy/rhabdomyolysis with which drug interactions:
Pregunta 82
Pregunta
What lab level should be checked if a patient complains of muscle pain while taking a statin?
Respuesta
-
Vitamin D
-
B12
-
Platelets
-
Hgb
Pregunta 83
Pregunta
T or F. New onset DM is less common with pravastatin and pitavastatin.
Pregunta 84
Pregunta
Before changing a patient to new statin. the NP should ensure the patient has been adhering to their current statin medication by checking:
Respuesta
-
BP
-
CMP
-
Lipid panel
-
Fasting Blood Glucose
Pregunta 85
Pregunta
T or F. Short acting statins like Lovastatin should be taken at bedtime?
Pregunta 86
Pregunta
Lower doses of rosuvastatin is recommended in which population?
Respuesta
-
African Americans
-
Latinos
-
Canadians
-
Asians
Pregunta 87
Pregunta
One of the advantages of zetia over statins is:
Pregunta 88
Pregunta
T or F. The MOA of Zetia is the inhibition of cholesterol at the small intestine.
Pregunta 89
Pregunta
PCSK9 Inhibitors like Alirocumab and Evolocumab:
Pregunta 90
Pregunta
T or F. Alirocumab must be stored in the refrigerator.
Pregunta 91
Pregunta
T or F. PCSK9 inhibitors should be avoided in pregnancy.
Pregunta 92
Pregunta
What is one way to decrease the flushing side effect that can come with the use of Niacin?
Pregunta 93
Pregunta
T or F. Fibrates are only taken to reduce high triglycerides.
Pregunta 94
Pregunta
Gemfibrozil and Fenofibrate should not be taken with statins because:
Respuesta
-
Increased risk for heart palpitations
-
Increase risk for drug interactions
-
They potentiate each other
-
Causes flushing
Pregunta 95
Pregunta
Fibrates should be avoided in (Select all that apply)
Pregunta 96
Pregunta
T or F. Statins can be used in children older than age ten with an elevated LDL.
Pregunta 97
Pregunta
Omega 3 Fatty Acids are helpful in reducing:
Respuesta
-
Trigylcerides
-
WBG
-
HDL
-
Muscle Pain