Lect 4 -Concepts and terminology

Descripción

Quiz on Concepts and terminology, created by Alannah McDonnell on 22/03/2018.
Alannah McDonnell
Test por Alannah McDonnell, actualizado hace más de 1 año
Alannah McDonnell
Creado por Alannah McDonnell hace más de 6 años
8
1

Resumen del Recurso

Pregunta 1

Pregunta
Flow rate is how much [blank_start]urine[blank_end] you are [blank_start]producing[blank_end] per unit of [blank_start]time[blank_end]
Respuesta
  • urine
  • urea
  • time
  • distance
  • producing
  • consuming
  • voiding

Pregunta 2

Pregunta
GFR is the amount of [blank_start]fluid[blank_end] going into [blank_start]bowmans capsule[blank_end] per unit of [blank_start]time[blank_end]
Respuesta
  • fluid
  • blood
  • bowmans capsule
  • the nephron
  • time
  • flow

Pregunta 3

Pregunta
what is normal glomerular flow rate?
Respuesta
  • 100-130ml/min
  • 500-600ml/min
  • 200-300ml/min

Pregunta 4

Pregunta
Filtered load is the same as
Respuesta
  • tubular load
  • GFR
  • Plasma concentration of a solute
  • electrolytes

Pregunta 5

Pregunta
[blank_start]Filtered load[blank_end] / tubular load is the [blank_start]amount of a specific solute[blank_end] ([blank_start]electrolyte, glucose or amino acid[blank_end]) entering [blank_start]bowman's capsule[blank_end].
Respuesta
  • Filtered load
  • amount of a specific solute
  • electrolyte, glucose or amino acid
  • electrolyte, carbohydrate or protein
  • salt
  • bowman's capsule
  • the kidney
  • the nephron

Pregunta 6

Pregunta
Filtered Load can be calculated from [blank_start]GFR[blank_end] and [blank_start]Plasma concentration of solute[blank_end]
Respuesta
  • GFR
  • blood flow
  • Plasma concentration of solute
  • blood concentration of solute
  • amount of urine produced

Pregunta 7

Pregunta
Inulin is....
Respuesta
  • freely filtered
  • not metabolised
  • not reabsorbed
  • not secreted

Pregunta 8

Pregunta
Inulin The excretion rate = ...
Respuesta
  • excretion rate
  • filtration rate
  • absorption rate
  • consumption rate

Pregunta 9

Pregunta
PAH is ...
Respuesta
  • freely filtered
  • not metabolised
  • not reabsorbed
  • freely secreted

Pregunta 10

Pregunta
What does clearance less than 125ml/min indicate?
Respuesta
  • reabsorption
  • secretion

Pregunta 11

Pregunta
What does clearance more than 125ml/min indicate?
Respuesta
  • secretion
  • absorption

Pregunta 12

Pregunta
What can be used to experimentally measure GFR?
Respuesta
  • Inulin
  • glucose
  • PAH
  • calcium

Pregunta 13

Pregunta
What is elevated Pcr an indicator of?
Respuesta
  • reduced GFR
  • increased GFR
  • non changing GFR

Pregunta 14

Pregunta
Threshold is....
Respuesta
  • appearance of solute in urine before you reach the overall Transport maximum of the kidney
  • the plasma concentration at which a substance begins to appear in the urine
  • the tiny amount of solute appearing in urine when a single nephron reaches its maximum
  • the total transport maximum through out all of the nephrons in the kidney

Pregunta 15

Pregunta
what is transport maximum?
Respuesta
  • the total transport maximum through out all of the nephrons in the kidney
  • The point at which an amount of solute appears in urine when nephrons reaches its maximum
  • the plasma concentration at which a substance begins to appear in the urine
  • appearance of solute in urine before you reach the overall threshold of the kidney
  • The maximum rate of the solute shuttling done by transporters

Pregunta 16

Pregunta
How can renal function be measured?
Respuesta
  • imaging techniques
  • renal clearance

Pregunta 17

Pregunta
The [blank_start]renal[blank_end] clearance value of a certain substance is the [blank_start]volume of plasma[blank_end] which is [blank_start]cleared of this substance[blank_end] by the kidney into urine [blank_start]/ min[blank_end].
Respuesta
  • renal
  • volume of plasma
  • volume of urine
  • cleared of this substance
  • / min

Pregunta 18

Pregunta
What do we need to know to measure renal clearance?
Respuesta
  • volume of urine / min
  • concentration of the substance mg/ml urine
  • concentration of the substance mg/ml plasma
  • concentration of the substance mg/ml blood
  • volume of substrate / min

Pregunta 19

Pregunta
What properties does a substance used in a plasma clearance test have?
Respuesta
  • does not enter RBCs
  • does not affect normal renal function
  • should not be metabolized by the kidney
  • should be easily measured in plasma & urine
  • should be non toxic
  • should be easy to consume

Pregunta 20

Pregunta
What do we use renal clearance for?
Respuesta
  • measurement of GFR
  • measurement of the renal plasma flow rate
  • determining the renal handling of the different substances; whether or not the substance is reabsorbed or secreted by the renal tubules

Pregunta 21

Pregunta
What is the rate-limiting step in the tubular transport of glucose?
Respuesta
  • Na-glucose symport
  • glucose uniporter
  • glucose reabsorption
  • ca- glucose symport

Pregunta 22

Pregunta
The plasma leaving the kidney through the renal veins lacks .....
Respuesta
  • the substances that are eliminated in the urine
  • proteins
  • plasma
  • the substances that are not eliminated in the urine

Pregunta 23

Pregunta
What is creatinine?
Respuesta
  • the end product of creatine metabolism
  • the end product of creatinine metabolism
  • a phospholipid
  • dumped into the blood by smooth muscle

Pregunta 24

Pregunta
Creatinine is continuously dumped into the blood by....
Respuesta
  • smooth muscle
  • skeletal muscle
  • cardiac muscle

Pregunta 25

Pregunta
the rate of creatinine appearance in blood is proportional to a person's ....
Respuesta
  • muscle mass
  • fat mass
  • urine excretion
  • blood

Pregunta 26

Pregunta
Creatinine is....
Respuesta
  • freely filtered
  • not reabsorbed
  • reabsorbed
  • not freely filtered

Pregunta 27

Pregunta
how much creatinine is secreted by the proximal tubule?
Respuesta
  • 10-20%
  • 40-50%
  • 70-80%
  • 85-100%

Pregunta 28

Pregunta
There is a ______________ between plasma creatinine concentration and GFR.
Respuesta
  • inverse correlation
  • indirect correlation
  • direct relationship
  • direct correlation

Pregunta 29

Pregunta
What is the most common method used for routine GFR assessments?
Respuesta
  • creatinine clearance
  • inulin clearance
  • PAH clearance
  • Plasma clearance

Pregunta 30

Pregunta
If there are more solutes present than can be transported, the solutes will end up...
Respuesta
  • In urine
  • Reabsorbed
  • In the blood stream
  • Excreted in faeces

Pregunta 31

Pregunta
Renal clearance is comparison of [blank_start]filtration[blank_end] rate of a substance to the rate of it's appearance in the [blank_start]urine[blank_end] i.e. Amount [blank_start]filtered[blank_end] vs amount [blank_start]excreted[blank_end]. It gives info on [blank_start]re-absorption[blank_end] and [blank_start]secretion[blank_end]
Respuesta
  • filtration
  • urine
  • urea
  • blood
  • filtered
  • excreted
  • re-absorption
  • secretion

Pregunta 32

Pregunta
What percentage of clearance?
Respuesta
  • A= ?% B=?% C=0% D=100%
  • A= 0% B=50% C=0% D=100%
  • A= 100% B=0% C=?% D=?%
  • A= 25% B=25% C=25% D=25%

Pregunta 33

Pregunta
Renal clearance principle is based on the principle of [blank_start]mass[blank_end] [blank_start]balance[blank_end]. Input of X is [blank_start]equal to[blank_end] output of X
Respuesta
  • mass
  • balance
  • equal to
  • more than
  • less than
  • pressure

Pregunta 34

Pregunta
fill in the formula
Respuesta
  • C
  • U
  • V
  • P

Pregunta 35

Pregunta
Tm for PAH secretory mechanism ~80mg/ml. PPAH [blank_start]<[blank_end] 80mg/ml = good estimation of RPF PPAH [blank_start]>[blank_end] 80mg/ml = poor estimation of RPF At [blank_start]low[blank_end] [blank_start]PPAH[blank_end]: [blank_start]PAH[blank_end] clearance [blank_start]=[blank_end] RPF
Respuesta
  • <
  • >
  • =
  • low
  • high
  • PPAH
  • PAH

Pregunta 36

Pregunta
Clearance units are [blank_start]volume[blank_end] per [blank_start]time[blank_end]
Respuesta
  • volume
  • time
  • distance
  • meter
  • second
  • pressure
  • flow

Pregunta 37

Pregunta
Clearance is not the amount of the [blank_start]substance removed[blank_end] but instead the volume of [blank_start]plasma from which it was removed[blank_end].
Respuesta
  • substance removed
  • plasma from which it was removed

Pregunta 38

Pregunta
PAH is an abbreviation of ...
Respuesta
  • para-aminohippurate
  • pilo-acidic-hormone
  • pregacilohinutrate
  • primary acid hilute
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