Pregunta 1
Pregunta
Parkinsons epidemiology: prevalence is [blank_start]0.5-1[blank_end]% in the UK in >[blank_start]60[blank_end]'s. it is the second most common neurodegenerative disorder after alzeheimers. the mean age of onset is [blank_start]45-60[blank_end] but it can occur in people as young as [blank_start]30[blank_end]. there are [blank_start]120,000[blank_end] people living with parkinsons in the UK.
Respuesta
-
0.5-1
-
1-1.5
-
1.5-2
-
2-2.5
-
60
-
50
-
70
-
80
-
45-60
-
50-65
-
55-70
-
60-75
-
30
-
20
-
25
-
35
-
120,000
-
100,000
-
80,000
-
140,000
Pregunta 2
Pregunta
which of the following is not a cause of parkinsons
Respuesta
-
heavy metal exposure
-
pesticide exposure
-
repeated head trauma
-
idiopathic
-
MPTP
-
genetics
-
excessive alcohol
Pregunta 3
Pregunta
parkinsons results from the loss of [blank_start]dopaminergic neurons[blank_end] in the [blank_start]basal ganglia[blank_end] most notably the [blank_start]substantia nigra[blank_end] which usually synthesises [blank_start]dopamine[blank_end]. surviving neutrons contain aggregations of protein ([blank_start]alpha-synuclein[blank_end]) called [blank_start]lewy bodies[blank_end]. symptoms are only seen once levels of dopamine are [blank_start]20-40%[blank_end] of normal. the disease is slowly progressive without remission.
Respuesta
-
dopaminergic neurons
-
basal ganglia
-
substantia nigra
-
dopamine
-
alpha-synuclein
-
lewy bodies
-
20-40%
Pregunta 4
Pregunta
which of the following is not part of the classic triad for parkinsons?
Respuesta
-
tremor
-
rigidity
-
bradykinesia
-
ataxic gait
Pregunta 5
Pregunta
which of the following is not a symptom of parkinsons?
Pregunta 6
Pregunta
what is the name of the scan that can be used to diagnose dementia? [blank_start]DAT[blank_end]
Pregunta 7
Pregunta
mark on the DAT scan which is normal and which is abnormal
Pregunta 8
Pregunta
what is the name of the criteria that can be helpful is diagnosing parkinsons? [blank_start]brain bank[blank_end]
Pregunta 9
Pregunta
In younger patients you would start by treating them with L-dopa instead of dopamine agonists
Pregunta 10
Pregunta
match each of the following types of parkinsons medication to the examples:
l-dopa - [blank_start]madapar[blank_end]
selective dopamine agonist - [blank_start]pramipexole[blank_end], [blank_start]bromocriptine[blank_end]
increases dopamine release - [blank_start]amantadine[blank_end]
MAO-B inhibitors - [blank_start]selegilene[blank_end]
COMTI - [blank_start]tolcapine[blank_end]
Respuesta
-
madapar
-
pramipexole
-
bromocriptine
-
amantadine
-
selegilene
-
tolcapine
Pregunta 11
Pregunta
never prescribe haloperidol for a parkinsons patients
Pregunta 12
Pregunta
which of the following is not a treatment for parkinsons?
Respuesta
-
L-dopa
-
pramipexole
-
bromocriptine
-
COMTI
-
MAOB-I
-
apomorphine
-
duodopa
-
surgery
-
amantadine
-
tamsulosin