Pregunta 1
Pregunta
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Pregunta 2
Pregunta
Direct-acting skeletal muscle relaxants interfere with __________ ions involved in skeletal muscle contraction.
Respuesta
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calcium
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phosphorus
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sodium
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magnesium
Pregunta 3
Pregunta
Neuromuscular blocking drugs work by:
Respuesta
-
a. disrupting nerve impulses at motor end plates
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b. disrupting nerve impulses at post-synaptic neurons
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c. both the above are true
Pregunta 4
Pregunta
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Pregunta 5
Pregunta
The __________ is that area where a terminal nerve ending innervates a muscle.
Pregunta 6
Pregunta
Curare alkaloids:
Respuesta
-
Paralyze the diaphragm preventing breathing
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Cross the blood-brain-barrier
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Make one go unconscious immediately
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Compete with phosphorus involved in muscle contraction
Pregunta 7
Pregunta
The antidote for curare alkaloids are __________ drugs.
Respuesta
-
anti-cholinesterase
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cholinesterase
Pregunta 8
Pregunta
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Pregunta 9
Pregunta
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Pregunta 10
Pregunta
Parkinson’s disease:
Respuesta
-
a. has a deficiency of dopamine
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b. has an excess of acetylcholine
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c. is a movement disorder
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d. all the above are true
Pregunta 11
Pregunta
Akinesia is the absence of:
Pregunta 12
Pregunta
The 2 types of therapy for Parkinson’s disease are __________ and __________ drugs.
Respuesta
-
anti-cholinergic; dopaminergic
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anti-cholinergic; anti-cholinesterase
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cholinergic; dopaminergic
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cholinergic; anti-cholinesterase
Pregunta 13
Pregunta
Another name for anti-cholinergic drugs is __________ drugs.
Respuesta
-
parasympatholytic
-
sympatholytic
Pregunta 14
Pregunta
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Pregunta 15
Pregunta
Dopaminergic drugs act on the brain to improve motor function.
Pregunta 16
Pregunta
Levodopa can convert to dopamine:
Pregunta 17
Pregunta
COMT inhibitors are reversible.
Pregunta 18
Pregunta
Triptans are used to treat:
Respuesta
-
musculoskeletal issues
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migraines
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seizures
-
Parkinson’s disease
Pregunta 19
Pregunta
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Respuesta
-
migraines
-
musculoskeletal issues
-
seizures
-
Parkinson’s disease
Pregunta 20
Pregunta
Abortive anti-migraine drugs are designed to stop a migraine: