Pregunta 1
Pregunta
Which are structural techniques?
Respuesta
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X-ray and CT
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MRI
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Contrast agents
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Diffusion Tensor Imaging
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PET
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fMRI
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EEG
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MEG
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ECoG
Pregunta 2
Pregunta
Which are functional techniques?
Respuesta
-
PET
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fMRI
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EEG
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MEG
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ECoG
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MRI
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CT
Pregunta 3
Pregunta
X-ray and CT techniques are great at showing:
Respuesta
-
Blood vessels
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Different brain regions
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Ventricles
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Electrical activity
Pregunta 4
Pregunta
_________ ventricles could be due to tumour; _________ ventricles could be due to schizophrenia
Respuesta
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Shrunken; expanded
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Expanded; shrunken
Pregunta 5
Pregunta
Which technique measures proton densities?
Respuesta
-
MRI
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Contrast agents
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PET
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Electrocorticography
Pregunta 6
Pregunta
What is the most common contrast agent?
Respuesta
-
Gadolinium
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TM tomato
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Haemoglobin
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Phosphorescents
Pregunta 7
Pregunta
What is true of Diffusion Tensor Imaging?
Respuesta
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Shows fibre tracts
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Measures hydrogen densities
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Is a structural MRI technique
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Water molecules diffuse more easily through the cross-section of neurons than along the long axis
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Makes a lot of assumptions
Pregunta 8
Pregunta
Which technique involves the injection of a radioactive isotope?
Respuesta
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CT
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PET
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Electrocorticography
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MEG
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Diffusion Tensor Imaging
Pregunta 9
Pregunta
What are examples of radioactive isotopes?
Respuesta
-
Oxygen
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Glucose
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Gadolinium
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Tm tomato
Pregunta 10
Pregunta
The brain takes about [blank_start]3[blank_end]% of the body's weight, but uses about [blank_start]20[blank_end]% of its nutrients
Pregunta 11
Pregunta
What is true of Regional Cerebral Blood Flow (rCBF)?
Respuesta
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Active regions release Nitrous Oxide to local arterioles
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Nitrous Oxide released retroactively
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Causes arterioles to constrict
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Very slow change
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Causes change in ratio of de:oxygenated blood
Pregunta 12
Pregunta
Which techniques are based on the close association between vasculature and metabolism?
Respuesta
-
fMRI
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PET
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EEG
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MEG
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Contrast agents
Pregunta 13
Pregunta
Which techniques measure electromagnetic fields generated by ionic current flow in active neurons?
Respuesta
-
EEG
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MEG
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fMRI
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PET
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Contrast agents
Pregunta 14
Pregunta
Which techniques are invasive?
Respuesta
-
MRI
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PET
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Electrocorticography
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EEG
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MEG
Pregunta 15
Pregunta
Which technique involves placing grids of electrodes directly on the surface of the brain?
Pregunta 16
Pregunta
When is Electrocorticography used?
Pregunta 17
Pregunta
What does MEG measure?
Respuesta
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Strength of magnetic field
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Strength of electrical field
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Location of magnetic field
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Location of electrical field
Pregunta 18
Pregunta
What is contained in a "dewer" and used to keep the SQUID close to absolute zero?
Respuesta
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Liquid helium
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Nitrous oxide
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Dry ice
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Hydrogen
Pregunta 19
Pregunta
Why do MRI scans have to be done after MEG?
Pregunta 20
Pregunta
Which technique induces electrical current flow by producing strong magnetic fields?
Pregunta 21
Pregunta
Which technique delivers a small electrical current?
Pregunta 22
Pregunta
Which is true of children's Fusiform gyrus response to faces, compared to adults:
Pregunta 23
Pregunta
What is true of standard template brains?
Respuesta
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Normalise brains
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Allows statistical analyses on brain maps
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Is a standard size and shape
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Used for structural brain images
Pregunta 24
Pregunta
Which standard template brain is based on a single well-characterised brain?
Respuesta
-
Talairach atlas
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MNI atlas
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Tesseract atlas
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Monoamine atlas
Pregunta 25
Pregunta
Which standard template brain is based on an average of hundreds of MRI scans?
Respuesta
-
MNI atlas
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Talairach atlas
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Tesseract atlas
Pregunta 26
Pregunta
When is fMRI mostly used?
Pregunta 27
Pregunta
When is MEG usually used?
Pregunta 28
Pregunta
What is true of hippocampal theta oscillations?
Respuesta
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Very active in novel environments
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Ties together place cells
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Tuned to specific locations in an environment
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Different place cells fire at different phases of the theta oscillation
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Important for semantic memory
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Measured by EEG
Pregunta 29
Pregunta
Which regions make up the Default Mode Network?
Respuesta
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Cingulate
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Parietal
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Frontal
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Temporal
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Occipital
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Limbic
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Diencephalonic
Pregunta 30
Pregunta
Which techniques are based on machine-learning?
Respuesta
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Connectivity
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Decoding
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Connectomics
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Machine reading
Pregunta 31
Pregunta
What is true of Connectivity analysis?
Respuesta
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Based on graph theory
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Emphasises brain structures over brain networks
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Multi-voxel pattern analysis
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Based on machine-learning
Pregunta 32
Pregunta
What is true of Decoding techniques?
Respuesta
-
Multi-voxel pattern analysis
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Analyses patterns of activity to complex stimuli
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Analyses patterns of activity to simple stimuli
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Based on graph theory
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Based on machine-learning
Pregunta 33
Pregunta
Why is the reproducibility crisis particularly acute in neuroimaging?
Respuesta
-
Huge amount of data
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Increased possibilty of false positives
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Too expensive to have large samples
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Large researcher degrees of freedom
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Statistical double-dipping
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Results tend to have a large impact on society
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Pre-registration of hypotheses
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Data sharing
Pregunta 34
Pregunta
How has fMRI improved?
Respuesta
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Gone from 1.5 T to 7 T
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Better image stability
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Better signal:noise ratio
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Strongest magnets can reslve activity in different cortical layers
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Higher temporal resolution
Pregunta 35
Pregunta
How has MEG improved?
Respuesta
-
Moving from SQUID to Optically Pumped Magnetometers
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Human Neocortical Neurosolver
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Dramatically improved data acquisition capabilities
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Strongest magnets can resolve activity in different cortical layers
Pregunta 36
Pregunta
What are Optically Pumped Magnetometers?
Respuesta
-
Require liquid helium
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Sensors placed directly on scalp
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But reduced signal:noise ratio
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Uses computers to map underlying circuit-level activity
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Only one place in the world has them
Pregunta 37
Pregunta
Why isn't neuroimaging useful for psychiatric diagnosis?
Respuesta
-
Low specificity
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High sensitivity
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High standardization
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Most psychiatric imaging studies are done on groups
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Different disorders have similar neural patterns
-
DSM has much higher validity
Pregunta 38
Pregunta
Who said that we are currently not able to use brain imaging for psychiatric diagnoses, and may not ever be?
Respuesta
-
Farah & Gillihan
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Aubertin & Bouillaud
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Flouren & Gerschwind
Pregunta 39
Pregunta
Aside from diagnosis, why might brain imaging be useful in psychiatry?
Respuesta
-
Can suggest new treatments
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DBS came from identifying deep brain areas that are hypoactive in depression
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Quantifying and predicting treatment response
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Classifying syndromes based on neuroimaging profile
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Real-time neurofeedback may be a treatment in itself