2808NRS Human Pathophysiology and Pharmacology 2 (Module 2)

Descripción

Module 2 EOT Exam Revision
Kathleen Jackson
Test por Kathleen Jackson, actualizado hace más de 1 año
Kathleen Jackson
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Resumen del Recurso

Pregunta 1

Pregunta
What is a low level of arterial oxygen termed?
Respuesta
  • hypocapnia
  • hypoxaemia
  • normoxia
  • hypoxia

Pregunta 2

Pregunta
Central cyanosis:
Respuesta
  • is due to the formation of excess oxyhaemoglobin
  • describes bluing colouration in the lips and linings of the mouth
  • is a consequence of cyanide poisoning
  • all answers are correct

Pregunta 3

Pregunta
Blood is considered to be acidotic as soon as:
Respuesta
  • blood pH remains at 7.4, but signs of acidosis are otherwise evident
  • blood pH rises above 7.4
  • blood pH falls below 7.0
  • blood pH falls below 7.35

Pregunta 4

Pregunta
Orthopnoea is:
Respuesta
  • noisy breathing with stridor or rhonchi.
  • difficulty breathing when lying down.
  • waking up suddenly, coughing, and struggling for breath.
  • very deep, rapid respirations.

Pregunta 5

Pregunta
Digital clubbing is a sign of:
Respuesta
  • chronic hypocapnia
  • chronic hyperoxia
  • chronic hypoxia
  • chronic hypercapnia

Pregunta 6

Pregunta
A 65-year-old female with emphysema presents to the ED for difficulty breathing. Physical exam reveals bluish skin and mucous membranes. This condition is referred to as:
Respuesta
  • haemoptysis
  • hypothermia
  • cyanosis
  • haematemesis

Pregunta 7

Pregunta
A 10-year-old female develops pneumonia following a urinary tract infection. Physical exam reveals subcostal and intercostal retractions. She reports that breathing is difficult and she feels she cannot get enough air. This condition is referred to as:
Respuesta
  • hyperpnoea
  • dyspnoea
  • orthopnoea
  • cyanosis

Pregunta 8

Pregunta
Reduced oxygenation of arterial blood is called:
Respuesta
  • hypoxaemia
  • ischaemia
  • hypoxia
  • hypocapnia

Pregunta 9

Pregunta
Paroxysmal nocturnal dyspnoea generally occurs with:
Respuesta
  • left ventricular failure
  • hypertension
  • pulmonary fibrosis
  • asthma

Pregunta 10

Pregunta
A 30-year-old male is experiencing respiratory failure. Which of the following lab values would be expected?
Respuesta
  • low Pa O2
  • normal blood pH
  • low PaCO2
  • electrolyte imbalances

Pregunta 11

Pregunta
A 1-year-old female is diagnosed with croup. Which of the following symptoms is most likely present?
Respuesta
  • respiratory stridor and barking cough
  • haemoptysis and mucus production
  • high fever and dry cough
  • drooling and snoring

Pregunta 12

Pregunta
A 30-year-old male prison inmate contracted tuberculosis during an outbreak. The organism that caused this condition is a:
Respuesta
  • fungus
  • bacterium
  • parasite
  • virus

Pregunta 13

Pregunta
A 1-year-old female is diagnosed with croup. The most likely cause of this disease is:
Respuesta
  • acute hyperventilation
  • bacterial infection
  • viral infection
  • allergy

Pregunta 14

Pregunta
A 6-month-old female presents with rhinorrhoea, cough, poor feeding, lethargy and fever. She is diagnosed with bronchiolitis. Which of the following is most likely causing her condition?
Respuesta
  • parainfluenza virus
  • respiratory syncytial virus
  • group A beta-haemolytic streptococcus
  • haemophilus B influenzae

Pregunta 15

Pregunta
This condition is an inflammatory response with extensive mucus production and submucosal oedema, resulting in widespread obstruction of bronchioles. It is of particular concern when present in infants.
Respuesta
  • bronchiolitis
  • tonsillitis
  • histoplasmosis
  • pneumonia

Pregunta 16

Pregunta
Pneumonia is caused by:
Respuesta
  • chronic lung changes seen with ageing
  • atelectasis
  • viral or bacterial infections
  • use of anaesthetic agents in surgery

Pregunta 17

Pregunta
What disease of the lungs is a contagious, airborne bacterial infection that causes fibrotic, calcified lesions that are visible on an X-ray?
Respuesta
  • legionellosis
  • tuberculosis
  • diphtheria
  • lobar pneumonia

Pregunta 18

Pregunta
This condition involves inflammation of the larynx, trachea and bronchi; is also known as laryngotracheobronchitis; involves copious mucus secretion; has a distinctive barking cough; and is potentially dangerous in infants.
Respuesta
  • rhinitis
  • laryngeal pneumonia
  • croup
  • pertussis

Pregunta 19

Pregunta
A 50-year-old male with a 30-year history of smoking was diagnosed with lung cancer. He was previously exposed to air pollution, asbestos and radiation at his job. Which of the following most likely had the greatest impact on development of his cancer?
Respuesta
  • radiation
  • cigarette smoke
  • asbestos
  • air pollution

Pregunta 20

Pregunta
Which type of lung cancer is most commonly associated with a history of smoking?
Respuesta
  • small cell carcinoma
  • squamous cell carcinoma
  • mesothelioma
  • adenocarcinoma

Pregunta 21

Pregunta
Clinical manifestations of acute sinusitis usually include:
Respuesta
  • bad breath and sore throat
  • copious frothy sputum and dyspnoea
  • severe localized pain in the facial bone and tenderness in the face
  • serous nasal discharge and chronic cough

Pregunta 22

Pregunta
What are typical signs and symptoms of epiglottitis?
Respuesta
  • Sudden fever, sore throat, and drooling saliva
  • Hyperinflation of the chest and stridor
  • Hoarse voice and barking cough
  • Sneezing, mild cough, and fever

Pregunta 23

Pregunta
A nurse is providing care for an older, previously healthy adult male has been diagnosed with pneumococcal pneumonia. Which of the following signs and symptoms is the nurse most likely to encounter?
Respuesta
  • The patient will lack lung consolidation and will have little sputum production.
  • High fever and chills, productive cough, crackles progressing to absence of breath sounds in affected lobes.
  • Copious bloody sputum and diffuse chest pain and may lose his cough reflex.
  • Hypotensive and afebrile and may manifest cognitive changes.

Pregunta 24

Pregunta
What would be the most effective compensation for chronic respiratory acidosis?
Respuesta
  • The kidneys reabsorbing more hydrogen ions
  • The kidneys producing more lactic acid
  • The kidneys eliminating more bicarbonate ions
  • The kidneys producing more bicarbonate ions

Pregunta 25

Pregunta
Which patient is most likely to have abnormalities in breathing regulation?
Respuesta
  • A 23-year-old male who has an injury to his frontal lobe following a sports injury
  • A 66-year-old male with temporal lobe infarcts secondary to a stroke
  • A 34-year-old male with damage to his upper and lower pons following a blow to the back of the head
  • A 45-year-old female with a spinal cord injury at C7 following a motor vehicle accident

Pregunta 26

Pregunta
The production of yellowish-green, cloudy, thick sputum is often an indication of:
Respuesta
  • damage of lung tissue due to smoking
  • emphysema
  • bacterial infection
  • cancer tumour

Pregunta 27

Pregunta
A 50-year-old male with diabetes did not take his medication and is now in metabolic acidosis. He is experiencing Kussmaul respirations that can be characterised by:
Respuesta
  • very slow inhalations and rapid expirations.
  • rapid respirations with periods of apnoea.
  • an increased ventilatory rate, large tidal volumes and no expiratory pause.
  • audible wheezing or stridor.

Pregunta 28

Pregunta
Which of the following describes lobar pneumonia?
Respuesta
  • Opportunistic bacteria causing low-grade fever with cough and thick greenish sputum
  • Viral infection causing nonproductive cough and pleuritic pain
  • Insidious onset, diffuse interstitial infection
  • Sudden onset of fever and chills, with rales and rusty sputum

Pregunta 29

Pregunta
What are early signs and symptoms of infectious rhinitis?
Respuesta
  • Copious purulent sputum, particularly in the morning.
  • Serous nasal discharge, congestion, and sneezing.
  • Harsh barking cough and wheezing.
  • Purulent nasal discharge and periorbital pain.

Pregunta 30

Pregunta
Anxiety-provoked hyperventilation will:
Respuesta
  • increase PCO2 quite markedly, and increase PO2 to a similar extent
  • decrease PCO2 quite markedly, and increase PO2 to small extent
  • increase PO2 significantly, and increase PCO2 slightly
  • will not affect PCO2 but will increase PO2 significantly

Pregunta 31

Pregunta
A 20-year-old male is in acute pain. An arterial blood gas reveals decreased carbon dioxide levels. Which of the following is the most likely cause?
Respuesta
  • hypoventilation
  • hyperventilation
  • pain neurons producing bicarbonate buffer
  • apnoea

Pregunta 32

Pregunta
Changes in PCO2 tend to affect the pH of blood.
Respuesta
  • False, blood pH is largely unaffected by PCO2.
  • True, and decreases in PCO2 tend to decrease pH.
  • True, and increases in PCO2 tend to decrease blood pH.
  • True, and increases in PCO2 tend to increase pH.

Pregunta 33

Pregunta
Obstruction in the upper airway is usually indicated by:
Respuesta
  • rales
  • wheezing
  • stridor
  • orthopnoea

Pregunta 34

Pregunta
A 28-year-old male complains to his GP that he has had a cold for a week and is coughing up bloody secretions. This condition is referred to as:
Respuesta
  • haematemesis.
  • haemoptysis.
  • cyanosis.
  • rhinitis.

Pregunta 35

Pregunta
How does severe hypoxia develop with pneumonia?
Respuesta
  • Oxygen diffusion is impaired by the congestion
  • Acidosis depresses respirations
  • Too painful to breath
  • Inflammatory exudate absorbs oxygen from the alveolar air

Pregunta 36

Pregunta
A 20-year-old male presents to his GP complaining of shortness of breath when lying down. This condition is referred to as:
Respuesta
  • dyspnoea on exertion.
  • orthostatic tachypnoea.
  • orthopnoea.
  • sleep apnoea.

Pregunta 37

Pregunta
A pneumonia that occurs 48 hours or more after admission to the hospital is considered
Respuesta
  • hospital-acquired pneumonia.
  • health care–associated.
  • viral pneumonia.
  • community-acquired pneumonia.

Pregunta 38

Pregunta
What would hypercapnia cause?
Respuesta
  • Respiratory acidosis
  • Decreased respirations
  • Decreased carbonic acid in the blood
  • Increased blood Ph

Pregunta 39

Pregunta
Light bubbly or crackling breathing sounds associated with serous secretions are called:
Respuesta
  • rhonchi
  • wheezing
  • rales
  • stridor

Pregunta 40

Pregunta
The extrinsic form of asthma is characterised by:
Respuesta
  • the release of chemical mediators from immune cells in lung tissue
  • an autonomic nervous system imbalance
  • the dominance of the parasympathetic stimulation of the airways
  • a tendency to develop in older individuals

Pregunta 41

Pregunta
Which one of the following antiasthma agents acts directly on intracellular cAMP levels?
Respuesta
  • Methylxanthines
  • β agonists
  • Leukotriene receptor antagonists
  • Muscarinic antagonists

Pregunta 42

Pregunta
A 13-year-old female is diagnosed with asthma. Which of the following should she recognise as part of an asthmatic attack?
Respuesta
  • bradycardia
  • headache
  • chest pain
  • wheezing

Pregunta 43

Pregunta
Asthma is thought to be caused by:
Respuesta
  • an autosomal recessive trait.
  • excessive use of antibiotics as a young child.
  • interactions between genetic and environmental factors.
  • autoimmunity.

Pregunta 44

Pregunta
In asthma, _____ is (are) reduced.
Respuesta
  • dead space
  • expiratory flow rates
  • lung volumes
  • air trapping

Pregunta 45

Pregunta
A 52-year-old female presents with chronic bronchitis. Tests reveal closure of the airway during expiration. This condition is most likely caused by:
Respuesta
  • thinning smooth muscle in the bronchioles
  • hyperventilation
  • ventilation-perfusion mismatch
  • thick mucus from hypertrophied glands

Pregunta 46

Pregunta
Individuals with a recent diagnosis of emphysema most often present with:
Respuesta
  • dyspnoea
  • cyanosis
  • cor pulmonale
  • a productive cough

Pregunta 47

Pregunta
A 53-year-old male with a 20-year history of smoking is diagnosed with emphysema. His airways are obstructed because of:
Respuesta
  • infection and inflammation
  • airway oedema
  • excessive mucous production
  • loss of elastic recoil

Pregunta 48

Pregunta
A 60-year-old female with emphysema is having difficulty expiring a given volume of air. She is most likely experiencing _____ pulmonary disease.
Respuesta
  • restrictive
  • pleuritic
  • atelectatic
  • obstructive

Pregunta 49

Pregunta
A 45-year-old male presents with chronic bronchitis of 5 months’ duration. Which of the following is most likely to cause this condition?
Respuesta
  • cigarette smoke
  • chronic asthma
  • air pollution
  • recurrent pneumonia

Pregunta 50

Pregunta
Which of the following activities does NOT require muscle contractions and energy?
Respuesta
  • Forced expiration
  • Quiet expiration
  • Quiet inspiration
  • Forced inspiration

Pregunta 51

Pregunta
Which of the following causes bronchodilation?
Respuesta
  • Drugs that block b2-adrenergic receptors
  • Noradrenaline
  • Histamine
  • Parasympathetic nervous system

Pregunta 52

Pregunta
What is the pathophysiology of an acute attack of extrinsic asthma?
Respuesta
  • Hyporesponsive mucosa
  • Continuous severe attacks unresponsive to medication
  • A hypersensitivity reaction involving release of chemical mediators
  • Gradual degeneration and fibrosis

Pregunta 53

Pregunta
Which of the following is typical of progressive emphysema?
Respuesta
  • Tidal volume increases.
  • Forced expiratory volume increases.
  • Residual lung volume increases.
  • Vital capacity increases.

Pregunta 54

Pregunta
Cystic fibrosis is transmitted as a/an:
Respuesta
  • chromosomal defect.
  • X-linked recessive gene.
  • autosomal dominant gene.
  • autosomal recessive gene.

Pregunta 55

Pregunta
Infant respiratory distress syndrome is initiated by:
Respuesta
  • excessive production of mucus and elastic tissue
  • insufficient production of mucus and elastic tissue
  • excessive production of surfactant
  • insufficient production of surfactant

Pregunta 56

Pregunta
An iatrogenic cause of pulmonary oedema is:
Respuesta
  • left sided heart failure
  • trauma resulting in pulmonary bleeding
  • incorrect insertion of nasogastric feeding tube
  • kidney failure

Pregunta 57

Pregunta
The term atelectasis describes:
Respuesta
  • fibrotic restriction on lung expansion
  • over inflation of the lungs
  • dilation of bronchi, but not of alveoli
  • partial or complete collapse of a lung

Pregunta 58

Pregunta
These inhaled particles are not able to be removal via phagocytosis, an are able to penetrate the alveolar wall. Prolonged exposure may lead to mesothelioma.
Respuesta
  • asbestos fibres
  • coal dust particles
  • silicate particles
  • all answers are correct

Pregunta 59

Pregunta
Restrictive lung disorders may be divided into two groups based on:
Respuesta
  • patient history of obesity and exposure to other COPD.
  • previous lung disease and cardiovascular disorders.
  • anatomical abnormality and lung disease damage, impairing expansion.
  • smoking history and congenital defects.

Pregunta 60

Pregunta
Which of the following is a manifestation of a simple closed pneumothorax?
Respuesta
  • Asymmetrical chest movements
  • Tracheal deviation toward the unaffected lung
  • Increased breath sounds on the affected side
  • Decreased respiratory rate

Pregunta 61

Pregunta
What is caused by frequent inhalation of irritating particles such as silica?
Respuesta
  • Frequent bronchospasm
  • Fibrosis and loss of compliance
  • Distorted shape of the thorax
  • Increased number of mucus-producing glands

Pregunta 62

Pregunta
Pulmonary oedema causes severe hypoxia because of:
Respuesta
  • interference with expansion of the lungs
  • decreased diffusion of carbon dioxide from the alveoli
  • decreased recoil of lungs and ineffective expiration
  • constant cough and haemoptysis

Pregunta 63

Pregunta
A COPD patient asks what medications are prescribed to help his breathing.
Respuesta
  • Atenolol, a beta-blocker
  • Salbutemol, a bronchodilator
  • Alprazolam, a benzodiazepine
  • Sildenafil, a vasodilator

Pregunta 64

Pregunta
Which of the following residents of a long-term care facility is most likely to be exhibiting the signs and symptoms of chronic obstructive pulmonary disease (COPD)?
Respuesta
  • An 81-year-old male who has a productive cough and recurrent respiratory infections
  • A 79-year-old lifetime smoker who is complaining of shortness of breath and pain on deep inspiration
  • An 81-year-old smoker who has increased exercise intolerance, a fever, and increased white blood cells
  • An 88-year-old female who experiences acute shortness of breath and airway constriction when exposed to tobacco smoke

Pregunta 65

Pregunta
The primary pathophysiological problem faced by sufferers of emphysema is:
Respuesta
  • bronchoconstriction
  • lack of expiratory recoil
  • inability to draw sufficient air into the upper airways
  • occlusion due to excessive mucus production

Pregunta 66

Pregunta
Which of the following should not be applied, or advised, to someone suffering chronic bronchitis?
Respuesta
  • keep well hydrated
  • cough suppressant
  • bronchodilator
  • mucolytic agents

Pregunta 67

Pregunta
A patient is in an urgent care center with an acute asthma attack, which medication will be used for initial treatment?
Respuesta
  • An anticholinergic such as ipratropium
  • A short-acting beta2 agonist
  • A corticosteroid
  • A long-acting beta2 agonist

Pregunta 68

Pregunta
A group of common chronic respiratory disorders characterized by tissue degeneration and respiratory obstruction is called:
Respuesta
  • Mesothelioma
  • COPD
  • CF
  • Pulmonary fibrosis

Pregunta 69

Pregunta
All of the following are expected with infant respiratory distress syndrome EXCEPT:
Respuesta
  • fluid and protein in the alveoli
  • pulmonary vasoconstriction
  • severe hypoxia
  • respiratory alkalosis

Pregunta 70

Pregunta
________ describes any parenchymal lung disease caused by inhalation of inorganic dusts.
Respuesta
  • Pneumonia
  • Infant Respiratory Distress syndrome
  • Pneumoconiosis
  • Hypersensitive pneumonitis

Pregunta 71

Pregunta
Which of the following clinical findings would be most closely associated with a client who has interstitial lung disease in comparison to chronic obstructive pulmonary disease (COPD)?
Respuesta
  • Increased FVC
  • Reduced FEV1/FVC
  • Decreased total lung capacity
  • Reduced expiratory flow rates

Pregunta 72

Pregunta
Transudative pleural effusion arises because of:
Respuesta
  • constriction of bronchial airways
  • decreased levels of proteins in blood
  • decreased capillary hydrostatic pressure
  • all answers are correct

Pregunta 73

Pregunta
Cystic fibrosis, as manifested in the lungs, is characterised by:
Respuesta
  • hyperplasia of smooth muscle cells
  • presence of abnormally viscous mucus
  • an abnormal fibrotic response
  • production of copious watery mucus

Pregunta 74

Pregunta
Which of the following is NOT a cause of pulmonary oedema?
Respuesta
  • Hyperproteinemia
  • Left-sided congestive heart failure
  • Inhalation of toxic gases
  • Excessive blood volume (overload)

Pregunta 75

Pregunta
Which statement does NOT apply to emphysema?
Respuesta
  • The surface area available for gas exchange is greatly reduced.
  • A genetic defect may lead to breakdown of elastic fibers.
  • Expiration is impaired.
  • The ventilation/perfusion ratio remains constant.

Pregunta 76

Pregunta
During an acute asthma attack, how does respiratory obstruction occur? 1. Relaxation of bronchial smooth muscle 2. Edema of the mucosa 3. Increased secretion of thick, tenacious mucus 4. Contraction of elastic fibers
Respuesta
  • 1, 2
  • 1, 3
  • 2, 3
  • 2, 4

Pregunta 77

Pregunta
Alpha-1 antitrypsin deficiency is associated with:
Respuesta
  • asthma
  • emphysema
  • cystic fibrosis
  • chronic bronchitis

Pregunta 78

Pregunta
Why does asthma result in fluid accumulation in the pulmonary interstitium?
Respuesta
  • because of pulmonary artery hypotension.
  • because of increased capillary permeability.
  • because of increased, internal mucous secretion.
  • None of the above; fluid may accumulate within the lumen of the airways, but it does not accumulate in the lung interstitium.

Pregunta 79

Pregunta
A patient is admitted for a relapse for sarcoidosis. Knowing this is usually caused by an inflammatory process, the nurse can anticipate administering.
Respuesta
  • a corticosteroid.
  • an salmeterol inhaler.
  • aspirin.
  • a bronchodilator.

Pregunta 80

Pregunta
Which of the following statements best captures the etiology of the acute response phase of extrinsic (atopic) asthma?
Respuesta
  • Chemical mediators are released from presensitized mast cells.
  • IgG production is heightened as a consequence of exposure to an allergen.
  • Epithelial injury and edema occur along with changes in mucociliary function.
  • Airway remodeling results in airflow limitations.

Pregunta 81

Pregunta
What is the cause of chronic bronchitis?
Respuesta
  • Deficit of enzymes, preventing tissue degeneration.
  • Hypersensitivity to parasympathetic stimulation in the bronchi.
  • Chronic irritation, inflammation, and recurrent infection of the larger airways.
  • A genetic defect causing excessive production of mucus.

Pregunta 82

Pregunta
Destruction of alveolar walls and septae is a typical change in:
Respuesta
  • cystic fibrosis.
  • emphysema.
  • acute asthma.
  • chronic bronchitis.

Pregunta 83

Pregunta
With a tension pneumothorax, which factors contribute to severe hypoxia?
Respuesta
  • More air leaving the pleural cavity on expiration than entering with inspiration.
  • Shift of the mediastinal contents toward the affected lung.
  • Decreasing compression of the inferior vena cava.
  • Continually increasing pressure on the unaffected lung.

Pregunta 84

Pregunta
Hypertrophy of goblet cells, decreased activity of the mucociliary escalator, and cor pulmonale, are most likely to occur in:
Respuesta
  • acute bronchitis
  • chronic bronchitis
  • asthma
  • early stage emphysema

Pregunta 85

Pregunta
Why does cor pulmonale develop with chronic pulmonary disease?
Respuesta
  • Demands on the left ventricle are excessive.
  • Pulmonary fibrosis and vasoconstriction increase vascular resistance.
  • Blood viscosity is increased, adding to cardiac workload.
  • The right ventricle pumps more blood than the left ventricle.

Pregunta 86

Pregunta
Loss of interstitial elasticity in the lungs is a hallmark of:
Respuesta
  • emphysema
  • chronic bronchitis
  • asthma
  • all of the above

Pregunta 87

Pregunta
Which of the following is typical of chronic bronchitis?
Respuesta
  • Decreased activity of the mucous glands
  • Overinflation of bronchioles
  • Air trapping by excessive mucus plugs
  • Formation of blebs or bullae on the lung surface

Pregunta 88

Pregunta
A physician is providing care for a child who has a diagnosis of cystic fibrosis (CF). Place the following pathphysiological events of CF in chronological order. 1) Airway obstruction 2) Recurrent pulmonary infections 3) Impaired Cl transport 4) Decreased water content of mucociliary blanket 5) Increased Na+ absorption
Respuesta
  • 1,4,3,5,2
  • 5,3,4,1,2
  • 3,5,4,1,2
  • 3,4,5,1,2

Pregunta 89

Pregunta
What causes the expanded anteroposterior (A-P) thoracic diameter (barrel chest) in patients with emphysema?
Respuesta
  • Dilated bronchi and increased mucous secretions
  • Recurrent damage to lung tissues
  • Air trapping and hyperinflation
  • Persistent coughing to remove mucus
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