Pharmacology- Fluoroquinolones- 4th Year PMU

Descripción

Pharmacology- Fluoroquinolones- 4th Year PMU
Med Student
Test por Med Student , actualizado hace más de 1 año
Med Student
Creado por Med Student hace casi 6 años
101
3

Resumen del Recurso

Pregunta 1

Pregunta
Fluoroquinoiones are:
Respuesta
  • Gentamycin
  • Moxifloxacin
  • Ciprofloxacin
  • Levofloxacin

Pregunta 2

Pregunta
Mechanism of action of quinolones is:
Respuesta
  • inhibition of protein synthesis
  • inhibition of cell wall synthesis
  • inhibition of topoisomerase II and IV
  • inhibition of DNA transcription and replication

Pregunta 3

Pregunta
Fluoroquinolones have:
Respuesta
  • broad antibacterial spectrum
  • narrow antibacterial spectrum
  • bacteriostatic effect
  • bactericidal effect

Pregunta 4

Pregunta
Point out the correct statements for pharmacokinetics of fluoroquinolones:
Respuesta
  • bad oral absorption and are administered always parenterally
  • distribute well into all tissues and body fluids
  • inhibit some liver cytochromes
  • most of them are excreted renally

Pregunta 5

Pregunta
Fluoroquinolones are used for treatment of:
Respuesta
  • Urinary tract infections
  • Respiratory infections
  • Skin infections
  • Gl infections

Pregunta 6

Pregunta
Adverse drug reactions of fluoroquinolones are:
Respuesta
  • articular cartilage erosion (arthropathy)
  • hypertension
  • seizures in patients with epilepsy
  • prolongation of QT interval

Pregunta 7

Pregunta
Quinolones are contraindicated in
Respuesta
  • pregnancy and breast-feeding
  • children under 18 years of age
  • patients with epilepsy
  • patients with renal failure

Pregunta 8

Pregunta
Drug interactions of fluoroquinolones are:
Respuesta
  • increase serum levels of theophyiline by inhibiting its metabolism
  • decrease serum levels of theophyiline by inducing its metabolism
  • synergism with beta-lactams
  • calcium and other divalent cations decrease their absorption
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