AntiFungal, Antiviral and Antimycobacerial Drugs- Pharmacology- 4th Year- PMU

Question

Antifungals are:

Answer 1

tetracyclines

Answer 2

imidazoles

Answer 3

echinocandims

Answer 4

Itraconazole

Answer 5

Ketoconazole

Answer 6

Fluconazole

Answer 7

Tetracycline

Answer 8

Gentamycin

Answer 9

Amphotericin B

Answer 10

are fungistatic

Answer 11

inhibit cell wall synthesis

Answer 12

inhibit ergosterol synthesis

Answer 13

inhibit hepatic CYP450 enzymes

Answer 14

Fluconazole and ltraconazole

Answer 15

Miconazole and Econazole

Answer 16

Given topically

Answer 17

Given systematically

Answer 18

the only imidazole that can be given orally

Answer 19

used for treatment of bacterial skin infections

Answer 20

used topically for cutaneous fungal infections

Answer 21

used intravenously for treatment of systemic fungal infections

Answer 22

it is non- steroidal anti-inflammatory drug

Answer 23

is triazole antifungal drug

Answer 24

is administered orally or intravenously

Answer 25

is excreted mainly unchanged with the urine

Answer 26

hepatotoxicity

Answer 27

endocrine disorders

Answer 28

nephrotoxicity

Answer 29

nausea, vomiting

Answer 30

has fungistatic activity

Answer 31

causes gastrointestinal disturbances

Answer 32

is effective against Trichomonas vaginalis

Answer 33

is effective against Candida species

Answer 34

renal impairment

Answer 35

hypokalemia

Answer 36

hypotension

Answer 37

liver impairment

Answer 38

inhibition of viral “uncoating”

Answer 39

inhibition of viral DNA or RNA synthesis

Answer 40

inhibition of viral proteases

Answer 41

inhibition of viral penetration into the cell

Answer 42

it inhibits viral DNA polymerase

Answer 43

it is used for “treatment of herpesvirus infections

Answer 44

it inhibits neuraminidase enzyme

Answer 45

can be applied topically, orally or intravenously

Answer 46

hepatotoxicity

Answer 47

renal impairment

Answer 48

local irritation

Answer 49

encephalopathy (at high i.v. doses)

Answer 50

Aciclovir (Zovirax)

Answer 51

Amantadin (Symmetrel)

Answer 52

Rimantadin (Flumadine)

Answer 53

Oseltamivir (Tamiflu)

Answer 54

interference with the function of the viral M2 protein

Answer 55

inhibition of specific neuraminidase enzyme

Answer 56

inhibition of reverse transcriptases

Answer 57

inhibition of proteases

Answer 58

resistance can develop rapidly

Answer 59

they are effective against both type A and type B influenza

Answer 60

they are effective against type A influenza viruses

Answer 61

they interfere with the function of the viral M2 protein and block uncoating of the Virus particles

Answer 62

inhibition of reverse transcriptase

Answer 63

inhibition of HIV protease

Answer 64

inhibition of HIV entry into the host cell

Answer 65

inhibition of the insertion of proviral DNA. into the host cell genome

Answer 66

it blocks HIV reverse transcriptase

Answer 67

it blocks HIV protease

Answer 68

it is a nucleoside analogue

Answer 69

it can cause anemia and neutropenia

Answer 70

peripheral neuropathy

Answer 71

pancreatitis

Answer 72

polymyositis

Answer 73

protease inhibition prevents maturation of the viral particles

Answer 74

they are enzyme inducers

Answer 75

they are enzyme inhibitors

Answer 76

they are combined with other antiretroviral drugs in the treatment of HIV infection

Answer 77

hyperlipidaemia

Answer 78

insulin resistance and hyperglycaemia

Answer 79

hypoglycaemia

Answer 80

fat redistribution

Answer 81

Telaprevir

Answer 82

Oseltamivir

Answer 83

Rifampicin

Answer 84

Ethambutol

Answer 85

Amoxicillin

Answer 86

is bactericidal antibiotic with antimycobacterial activity

Answer 87

is antiviral drug

Answer 88

is broad spectrum antibiotic

Answer 89

is enzyme inducer

Answer 90

inhibition of cell wall synthesis

Answer 91

inhibition of 50 S ribosomal subunit

Answer 92

inhibition of DNA-dependent RNA polymerase

Answer 93

increased cell membrane permeability

Answer 94

heart failure

Answer 95

orange-red color of urine and other secretions

Answer 96

hepatotoxicity

Answer 97

hypoglycaemia

Answer 98

inhibits the synthesis of essential for mycobacteria mycolic acid

Answer 99

it is metabolized by, acetylation

Answer 100

it is specific for treatment of M. Tuberculosis

Answer 101

it is active against broad spectrum of bacteria

Answer 102

renal impairment

Answer 103

peripheral neuropathy

Answer 104

convulsions

Answer 105

supplementation with vitamin B1

Answer 106

supplementation with vitamin A

Answer 107

supplementation with vitamin B6

Answer 108

supplementation with vitamin B12

Answer 109

hepatotoxicity

Answer 110

arrhythmia

Answer 111

hyperuricaemia

Answer 112

hypoglycaemia

Answer 113

is bacteriostatic antimycobacterial drug

Answer 114

may cause liver failure

Answer 115

may cause optic neuritis

Answer 116

inhibits synthesis of the mycobacterial cell wall

Siguiente

AntiFungal, Antiviral and Antimycobacerial Drugs- Pharmacology- 4th Year- PMU

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