Cholinergic Drugs- Pharmacology 4th Year- PMU

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Cholinergic Drugs- Pharmacology 4th Year- PMU
Med Student
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Med Student
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Resumen del Recurso

Pregunta 1

Pregunta
Point out the cholinergic neurons
Respuesta
  • preganglionic sympathetic
  • postganglionic sympathetic
  • preganglionic parasympathetic
  • postganglionic parasympathetic

Pregunta 2

Pregunta
Muscarinic cholinergic receptors are located in:
Respuesta
  • skeletal muscles
  • bronchial smooth muscles
  • heart
  • smooth muscles of GIT

Pregunta 3

Pregunta
Nicotinic cholinergic receptors are located in:
Respuesta
  • autonomic ganglia
  • adrenal gland medulla
  • heart muscle
  • skeletal muscles

Pregunta 4

Pregunta
Pharmacological effects of Acetylcholine are:
Respuesta
  • bradycardia
  • tachycardia
  • increased digestive (abundant saliva), bronchial, cutaneous, (sweat) and lacrimal secretions
  • increased tone and peristaltic contractions of GIT

Pregunta 5

Pregunta
M-receptor agonist used for treatment of glaucoma is:
Respuesta
  • Atropini sulfas
  • Pilocarpini hydrochloridum
  • Neostigmini methylsulfas
  • Galantamini bromidum

Pregunta 6

Pregunta
What are the effects of Pilocarpine after eye application?
Respuesta
  • mydriasis
  • miosis
  • increases the intraocular pressure
  • decreases the intraocular pressure

Pregunta 7

Pregunta
Clinical indications for prescribing N-receptor agonists are:
Respuesta
  • smoking cessation
  • atherosclerosis
  • premedication in anesthesia
  • muscle relaxation

Pregunta 8

Pregunta
Acetylcholine esterase inhibitors (anticholinesterases) are:
Respuesta
  • lpratropii bromidum
  • Galantamine bromidum
  • Neostigmine methylsulfas
  • Pyridostigmine bromidum

Pregunta 9

Pregunta
Indications for the clinical use of anticholinesterases are:
Respuesta
  • paralytic ileus
  • atropine intoxication
  • spastic bronchitis
  • as antidote of tubocurarine

Pregunta 10

Pregunta
Anticholinesterases are contraindicated in:
Respuesta
  • bronchial asthma
  • paralytic ileus
  • epilepsy
  • bradycardia

Pregunta 11

Pregunta
Point out the major features of the irreversible acetylcholine-esterase inhibitors:
Respuesta
  • They are organophosphate agents
  • Cause long-lasting elevation of acetylcholine levels
  • Their effect is antagonized by cholinolytic agents
  • Obidoxime is their specific antagonist

Pregunta 12

Pregunta
Symptoms of organophosphate intoxication can be treated with:
Respuesta
  • Acetylcholine
  • Atropine sulphas
  • Reactivators of acetylcholine esterase enzyme
  • Inhibitors of acetylcholine esterase

Pregunta 13

Pregunta
Antimuscarinic receptor antagonists are:
Respuesta
  • Atropini sulfas
  • Butylscopolamine
  • Atracurium besilas
  • Ipratropium bromidum

Pregunta 14

Pregunta
Synthetic antimuscarinic drugs are:
Respuesta
  • Pilocarpini hydrochloridum
  • Ipratropium bromidum
  • Butylscopolamine
  • Tiotropium bromidum

Pregunta 15

Pregunta
Pharmacological effects of antimuscarinic drugs are:
Respuesta
  • tachycardia
  • intestinal smooth muscle relaxation
  • mydriasis
  • decrease the secretion of exocrine glands

Pregunta 16

Pregunta
Clinical indications for prescribing antimuscarinic drugs are:
Respuesta
  • bronchial asthma
  • spasm of the smooth muscles of GlT
  • to elicit papillary dilation
  • glaucoma

Pregunta 17

Pregunta
Adverse drug reactions of Atropine are:
Respuesta
  • dry mouth
  • tachycardia
  • difficulties in seeing close objects
  • disorientation and hallucinations

Pregunta 18

Pregunta
Symptoms of intoxication with antimuscarinic agents are treated with:
Respuesta
  • Obidoxime
  • Anticholinesterases
  • Atropine sulphas
  • Acetylcholine

Pregunta 19

Pregunta
Non-depolarizing neuromuscular blockers paralyse the skeletal muscles in the following order:
Respuesta
  • head and neck, limbs, trunk, diaphragm and intercostal muscles
  • limbs, trunk, diaphragm and intercostal muscles, head and neck
  • diaphragm and intercostal muscles, head and neck, limbs
  • trunk, diaphragm and intercostal muscles, head and neck, limbs

Pregunta 20

Pregunta
Which of the following drugs are non-depolarising muscle blockers?
Respuesta
  • Atracurium besilas
  • Pancuronium bromidum
  • Suxamethonium chloridum
  • Tubocurarine hydrochloridum

Pregunta 21

Pregunta
Adverse drug reactions of non-depolarizing muscle relaxants are:
Respuesta
  • histamine release
  • hypotension
  • hypertension
  • allergic reaction

Pregunta 22

Pregunta
Drug interactions can occur in concomitant use Of peripheral-acting muscle relaxants and:
Respuesta
  • aminoglycoside antibiotics
  • calcium antagonists
  • halogen anaesthetics
  • cardiac glycosides

Pregunta 23

Pregunta
Which of the following drugs will antagonise the effect of the non-depolarizing neuromuscular blockers?
Respuesta
  • Anticholinesterases
  • MAO inhibitors
  • Antimuscarinic agents
  • Aminoglycoside antibiotics

Pregunta 24

Pregunta
What are the main features of Suxamethonium chioridum:
Respuesta
  • short-lasting effect
  • has no antagonist
  • anticholinesterases prolong its effect
  • oral administration

Pregunta 25

Pregunta
Adverse drug reactions of depolarizing muscle relaxants are-
Respuesta
  • tremor
  • arrhythmia
  • allergic reactions
  • prolonged neuromuscular blockade in people with plasma cholinesterase deficiency

Pregunta 26

Pregunta
Indications for treatment with central muscle relaxants are-
Respuesta
  • spasms of the skeletal muscles as a result of CNS damage
  • multiple sclerosis
  • surgery interventions
  • myasthenia gravis

Pregunta 27

Pregunta
Which of drugs are central acting muscle relaxants?
Respuesta
  • Tetrazepam
  • Tolperison
  • Bromocriptine
  • Baclofen
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