15922111
Descripción
Test por Jennifer Keough, actualizado hace más de 1 año
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Creado por Jennifer Keough
hace alrededor de 6 años
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Pregunta 1
Pregunta
Centrally-acting skeletal muscle relaxants are basically Central Nervous System depressants.
Respuesta
- True
- False
Pregunta 2
Pregunta
Direct-acting skeletal muscle relaxants affect:
Respuesta
-
a. skeletal muscle
-
b. cardiac muscle
-
c. smooth muscle
-
d. all the above are true
Pregunta 3
Pregunta
Neuromuscular blocking drugs work by:
Respuesta
-
a. disrupting nerve impulses at motor end plates
-
b. disrupting nerve impulses at post-synaptic neurons
-
c. both the above are true
Pregunta 4
Pregunta
Depolarizing neuromuscular blocking drugs are derived from curare alkaloids.
Respuesta
- True
- False
Pregunta 5
Pregunta
The ________________ is that area where a terminal nerve ending innervates a muscle.
Respuesta
-
a. motor end plate
-
b. synaptic cleft
-
c. both the above are true
Pregunta 6
Pregunta
Curare alkaloids:
Respuesta
-
Paralyze the diaphragm preventing breathing
-
cross the blood-brain-barrier
-
make one go unconscious immediately
-
compete with phosphorus involved in muscle contractions
Pregunta 7
Pregunta
The antidote for curare alkaloids are ____________ drugs.
Respuesta
-
anti-cholinesterase
-
cholinesterase
Pregunta 8
Pregunta
Depolarizing neuromuscular blocking drugs cannot be inactivated by cholinesterase.
Respuesta
- True
- False
Pregunta 9
Pregunta
Succinylcholine is metabolized slower than acetylcholine, resulting in:
Respuesta
-
Longer muscle paralysis
-
Shorter muscle paralysis
-
Succinylcholine has nothing to do with muscle paralysis
Pregunta 10
Pregunta
What are the movement disorders associated with Parkinson's disease?
Respuesta
-
a. Muscle rigidity
-
b. Akinesia
-
c. Tremors at rest
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d. Posture/balance disturbances
-
e. a and d are correct
-
f. c and d are correct
-
g. All the above are correct
Pregunta 11
Pregunta
Akinesia is the absence of:
Respuesta
-
the power of voluntary movement
-
the ability to think
-
diaphragmatic movement
-
the ability of speech
Pregunta 12
Pregunta
The 2 types of therapy for Parkinson's disease are _____________ and ______________ drugs.
Respuesta
-
anti-cholinergic; dopaminergic
-
anti-cholinergic; anti-cholinesterase
-
cholinergic; dopaminergic
-
cholinergic; anti-cholinersterase
Pregunta 13
Pregunta
Anti-cholinergic drugs inhibit acetylcholine action at parasympathetic receptors.
Respuesta
- True
- False
Pregunta 14
Pregunta
Too much acetylcholine will excite the CNS causing parkinsonian tremor.
Respuesta
- True
- False
Pregunta 15
Pregunta
Dopaminergic drugs act on the brain to improve motor function.
Respuesta
- True
- False
Pregunta 16
Pregunta
Dopaminergic drugs act on the brain to improve motor function.
Respuesta
- True
- False
Pregunta 17
Pregunta
Lavodopa can convert to dopamine:
Respuesta
-
a. before crossing the blood-brain-barrier
-
b. after crossing the blood-brain-barrier
-
c. both the above are true
Pregunta 18
Pregunta
COMT stands for:
Respuesta
-
a. Catechol-O-methyltransferase
-
b. Catechol-OH-methyltransacetylase
-
c. Catecholamine-O-methyltransacetylase
-
d. none of the above are correct
Pregunta 19
Pregunta
Another name of 5-HT1-receptor agonists is triptans.
Respuesta
- True
- False
Pregunta 20
Pregunta
5-HT1-receptor agonists and ergotamine preparations are both used in the treatment of:
Respuesta
-
migraines
-
musculoskeletal issues
-
seizures
-
Parkinson's disease
Pregunta 21
Pregunta
Depolarizing neuromuscular blocking drugs act like ____________.
Respuesta
-
acetylcholine
-
norepinephrine
-
epinephrine
-
dopamine
Pregunta 22
Pregunta
Physical and psychological dependence are major adverse effects of direct-acting skeletal muscle relaxants.
Respuesta
- True
- False
Pregunta 23
Pregunta
Direct-acting skeletal muscle relaxants interfere with ___________ ions involved in skeletal muscle contraction:
Respuesta
-
sodium
-
calcium
-
magnesium
-
phosphorus
Pregunta 24
Pregunta
Parkinson's disease:
Respuesta
-
a. has a deficiency of dopamine
-
b. has an excess of acetylcholine
-
c. is a movement disorder
-
d. all the above are true
Pregunta 25
Pregunta
Another name for anti-cholinergic drugs is ____________ drugs.
Respuesta
-
parasympatholytic
-
sympatholytic
Pregunta 26
Pregunta
COMT inhibitors are reversible.
Respuesta
- True
- False
Pregunta 27
Pregunta
Triptans are used to treat:
Respuesta
-
seizures
-
musculoskeletal issues
-
Parkinson's disease
-
migraines
Pregunta 28
Pregunta
Abortive anti-migraine drugs are designed to stop a migraine:
Respuesta
-
a. after it starts
-
b. before it starts
-
c. both the above are correct
-
d. neither of the above are correct
Pregunta 29
Pregunta
Levodopa needs passage through the blood-brain-barrier to become effective.
Respuesta
- True
- False
Pregunta 30
Pregunta
Carbidopa enhances the effectiveness of Levodopa by preventing its peripheral conversion to dopamine.
Respuesta
- True
- False
Pregunta 31
Pregunta
COMT inhibitors are used in Parkinson patients when the initial therapy begins to wear off.
Respuesta
- True
- False
Pregunta 32
Pregunta
Contraindication for taking triptans includes:
Respuesta
-
a. Ischemic
-
b. Cerebrovascular
-
c. Coronary artery disease
-
d. All the above are correct
Pregunta 33
Pregunta
Anti-cholinergic drugs inhibit acetylcholine action at sympathetic receptors.
Respuesta
- True
- False
Pregunta 34
Pregunta
For epilepsy and seizures a(an) ______________ drug is usually recommended.
Respuesta
-
a. anti-migraine
-
b. COMT inhibitor
-
c. dopaminergic
-
d. anti-convulsant
Pregunta 35
Pregunta
To have a higher conversion to dopamine after passing through the blood-brain-barrier, one needs to take ______________.
Respuesta
-
a. Levodopa
-
b. Carbidopa
-
c. Levodopa and Carbidopa
-
d. None of the above drugs have anything to do with dopamine
Pregunta 36
Pregunta
Anti-convulsant drugs:
Respuesta
-
a. Stabilize nerve cells from over excitement
-
b. Elevate seizure thresholds
-
c. Inhibit neuromuscular transmission
-
d. Increase GABA
-
e. All the above are correct
Pregunta 37
Pregunta
The neurotransmitter released at motor end plates is:
Respuesta
-
a. Norepinephrine
-
b. Dopamine
-
c. Acetylcholine
-
d. Epinephrine
Pregunta 38
Pregunta
The effectiveness of ergotamine preparations is increased by drinking coffee.
Respuesta
- True
- False
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